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Engineering Technologies for Acute Trauma Care

Award Number: R01EB036076
ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/01/2025
PERIOD OF PERFORMANCE END DATE: 01/31/2029

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Engineering Technologies for Acute Trauma Care - PROJECT SUMMARY Trauma-related injuries, such as from motor vehicle accidents, accidental falls or acts of violence, are the 3rd leading cause of death in the United States, and the leading cause of death for those between 1 and 46 years of age. Damage control resuscitation is initiated by first responders to restore tissue perfusion and oxygen delivery while preventing complications associated with aggressive resuscitation efforts. However, as most interventions for addressing bleeding rely on blood product transfusions, limited treatments are available for use outside the hospital setting. The goal of this proposal is to engineer novel, synthetic therapies for stabilizing trauma victims in the critical “golden hour” after injury. Our main objectives are to develop low volume resuscitants that provide fluid resuscitation while preserving the patient’s coagulation system and immune- modulating polymers that attenuate inflammation and neutralize reactive oxygen species. Successful completion of these aims will lead to new and critically-needed innovations for trauma medicine.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $468,326 )
2026	2026	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	2/2/2026	NON-COMPETING CONTINUATION	$468,326
														Subtotal = $468,326

Issue Date FY: 2025 ( Subtotal = $580,017 )
2025	2025	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	1	7/3/2025	NEW	$72,500
2025	2025	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	2/25/2025	NEW	$507,517
														Subtotal = $580,017

Grand Total All Awards = $1,048,343

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Engineering Technologies for Acute Trauma Care

Award Number: R01EB036076

ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/01/2025

PERIOD OF PERFORMANCE END DATE: 01/31/2029

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