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Evaluation of a Remotely-Delivered Behavioral Intervention for Post-Bariatric Surgery Weight Regain

Award Number: R01DK133264
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2023
PERIOD OF PERFORMANCE END DATE: 05/31/2028

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Evaluation of a Remotely-Delivered Behavioral Intervention for Post-Bariatric Surgery Weight Regain - PROJECT SUMMARY/ABSTRACT The proposed study is designed to evaluate the efficacy of a remotely-delivered, acceptance-based behavioral intervention (ABTi) for individuals demonstrating weight regain after bariatric surgery by comparing it to a Control condition. The current study aims to: 1) evaluate ABTi's efficacy on weight outcomes compared to Control; 2) evaluate ABTi's efficacy on secondary outcomes including improvements in eating behaviors, physical activity, and medical conditions compared to Control; 3) test proposed mechanisms of action, including evaluating a) if changes in hypothesized active ingredients in ABTi mediate differences in weight outcomes between conditions and b) if the association between eating behavior and subjective internal states (i.e., hunger, cravings, urges, negative affect) will weaken in ABTi compared to Control. Patients 6 to 48 months out from surgery who have regained >5% of their weight will be randomized to ABTi or Control (n=200). Assessments willbe conducted at baseline, 3, 6 (end of active treatment), and 12 months (follow up) after enrollment. Developing innovative interventions to reverse postoperative weight regain is crucial to maintain the health benefits of surgery in this growing population of patients not experiencing optimal postoperative results.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $634,546 )
2025	2025	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1805 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	3	7/9/2025	NON-COMPETING CONTINUATION	$634,546
														Subtotal = $634,546

Issue Date FY: 2024 ( Subtotal = $643,815 )
2024	2024	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1805 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	2	6/28/2024	NON-COMPETING CONTINUATION	$643,815
														Subtotal = $643,815

Issue Date FY: 2023 ( Subtotal = $692,476 )
2023	2023	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	8/31/2023	NEW	$692,476
														Subtotal = $692,476

Grand Total All Awards = $1,970,837

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Evaluation of a Remotely-Delivered Behavioral Intervention for Post-Bariatric Surgery Weight Regain

Award Number: R01DK133264

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2023

PERIOD OF PERFORMANCE END DATE: 05/31/2028

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