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CRCNS: Building and testing computational models of the neural basis of natural communication

Award Number: R01DC022534
ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2024
PERIOD OF PERFORMANCE END DATE: 08/31/2029

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CRCNS: Building and testing computational models of the neural basis of natural communication - Communication and language processing disorders can significantly impact the lives of millions of people. The proposed Conversations project will combine an unprecedented ECoG dataset and a cutting-edge MLbased encoding framework to test competing models for neural mechanisms supporting natural language processing and face-to-face communication in natural contexts. Uncovering the neural mechanisms behind everyday communication can give voice to people with speech and hearing impairments, shed light on communication disorders, and enhance doctor-patient communication. In Aim 1, we will create the 24/7 Conversations dataset of 750 hrs of continuous electrocorticography (ECoG) data from epilepsy patients engaging in free daily life conversations. This dataset will be the largest collection of real-life conversations and intracranial neural activity assembled. Aim 2 involves developing an ML-based encoding framework to test the ability of various language models to model our 24/7 Conversations dataset. ML-based encoding framework will allow us to explore brain-to-brain communication dynamics during face-to-face conversations. Finally, Aim 3 will leverage the ML-based encoding framework to construct novel computational models that simulate the neural basis of natural language processing, focusing on how the brain predicts and integrates spoken language during spontaneous real-life conversations. Through these efforts, we aim to map the intricate neural activities associated with language, providing insights into normal and disordered communication.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $363,683 )
2026	2026	THE TRUSTEES OF PRINCETON UNIVERSITY	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Research Related to Deafness and Communication Disorders	000	3	8/18/2026	NON-COMPETING CONTINUATION	$363,683
														Subtotal = $363,683

Issue Date FY: 2025 ( Subtotal = $407,640 )
2025	2025	THE TRUSTEES OF PRINCETON UNIVERSITY	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Research Related to Deafness and Communication Disorders	000	2	8/18/2025	NON-COMPETING CONTINUATION	$407,640
														Subtotal = $407,640

Issue Date FY: 2024 ( Subtotal = $409,280 )
2024	2024	THE TRUSTEES OF PRINCETON UNIVERSITY	1 NASSAU HALL	PRINCETON	NJ	08544	MERCER	USA	Research Related to Deafness and Communication Disorders	000	1	8/12/2024	NEW	$409,280
														Subtotal = $409,280

Grand Total All Awards = $1,180,603

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CRCNS: Building and testing computational models of the neural basis of natural communication

Award Number: R01DC022534

ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2024

PERIOD OF PERFORMANCE END DATE: 08/31/2029

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