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Identification of treatment parameters that maximize language treatment efficacy for children.

Award Number: R01DC015642
ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Abstract Poor language skills are associated with numerous negative outcomes ranging from higher rates of tantrums and difficulty developing friendships to school failure, contact with the justice system, and increased victimization. Although language deficits may be noticed as early as toddlerhood, effective treatment may not begin this early and there is relatively little time to close the language gap before these children are faced with the increased language demands of formal education and the cumulative effects of academic struggle. For the 7-13% of children with impaired language skills, language treatments that are faster and more effective are urgently needed. This competing renewal addresses this need with a series of studies that translate basic research in statistical learning to treatment contexts. The Statistical Learning Framework posits learners extract word meaning and grammatical structure from the language input they receive, and the statistical structure of the input accounts for rapid, implicit language learning. Six proposed studies translate statistical learning principles to a treatment context. Theoretically-motivated treatment factors are tested in two groups of children with poor language skills. “Late Talkers” are children (ages 2-3 years) who are identified by the very limited number of vocabulary words that they understand and use. Preschool children with Developmental Language Disorder (ages 4-5 years) show marked deficits in the use of grammatical morphemes. Parallel studies targeting vocabulary treatment (for Late Talkers) and morphosyntax treatment (for children with DLD) will test whether leveraging prior learning can improve treatment methods by making learning faster and more effective. We will also directly address the issue of non-responders (i.e., children who make limited improvement despite treatment that is effective for others), an unaddressed problem inherent to all treatment research. We leverage our previous findings to predict which children are highly likely to be non-responders and propose alternative treatment methods that might assist this subset of children. These studies represent the necessary work for principled language treatment that is supported by evidence, and can provide insights into the nature of learning in a range of children with poor language skills.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $641,329 )
2024	2024	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Research Related to Deafness and Communication Disorders	000	8	8/28/2024	NON-COMPETING CONTINUATION	$641,329
														Subtotal = $641,329

Issue Date FY: 2023 ( Subtotal = $1,218,499 )
2023	2023	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Research Related to Deafness and Communication Disorders	003	7	8/29/2023	NON-COMPETING CONTINUATION	$641,329
2023	2023	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Research Related to Deafness and Communication Disorders	002	6	6/16/2023	SUPPLEMENT FOR EXPANSION	$577,170
2023	2022	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Research Related to Deafness and Communication Disorders	001	6	5/12/2023	COMPETING CONTINUATION	$248
2023	2020	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Research Related to Deafness and Communication Disorders	000	5	5/12/2023	NON-COMPETING CONTINUATION	-$248
														Subtotal = $1,218,499

Issue Date FY: 2022 ( Subtotal = $641,329 )
2022	2022	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Research Related to Deafness and Communication Disorders	000	6	3/4/2022	COMPETING CONTINUATION	$641,329
														Subtotal = $641,329

Issue Date FY: 2020 ( Subtotal = $606,922 )
2020	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Research Related to Deafness and Communication Disorders	000	5	6/16/2020	NON-COMPETING CONTINUATION	$606,922
														Subtotal = $606,922

Issue Date FY: 2019 ( Subtotal = $606,922 )
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Research Related to Deafness and Communication Disorders	000	4	6/25/2019	NON-COMPETING CONTINUATION	$606,922
														Subtotal = $606,922

Issue Date FY: 2018 ( Subtotal = $606,922 )
2018	2018	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Research Related to Deafness and Communication Disorders	000	3	6/21/2018	NON-COMPETING CONTINUATION	$606,922
														Subtotal = $606,922

Issue Date FY: 2017 ( Subtotal = $606,922 )
2017	2017	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Research Related to Deafness and Communication Disorders	000	2	6/13/2017	NON-COMPETING CONTINUATION	$606,922
														Subtotal = $606,922

Issue Date FY: 2016 ( Subtotal = $606,922 )
2016	2016	UNIVERSITY OF ARIZONA	POST OFFICE BOX 3308	TUCSON	AZ	85722		USA	Research Related to Deafness and Communication Disorders	000	1	6/15/2016	NEW	$606,922
														Subtotal = $606,922

Grand Total All Awards = $5,535,767

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Identification of treatment parameters that maximize language treatment efficacy for children.

Award Number: R01DC015642

ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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