Saturday, October 5, 2024 10/5/2024

Functional organization of the superior temporal gyrus for speech perception

Award Number: R01DC012379
ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY The basic mechanisms underlying comprehension of spoken language are still largely unknown. Over the past decade, we have gained new insights to how the human brain extracts the most fundamental linguistic elements (consonants and vowels) from a complex and highly variable acoustic signal. However, the next set of questions await pertaining to the sequencing of those auditory elements and how they are integrated with other features, such as, the amplitude envelope of speech. Further investigation of the cortical representation of speech sounds can likely shed light on these fundamental questions. Previous research has implicated the superior temporal cortex in the processing of speech sounds, but little is known about how these sounds are linked together into the perceptual experience of words and continuous speech. The recording of neural activity directly from the cortical surface is a promising approach to study this since it can provide both high spatial and temporal resolution. This proposal seeks to examine the mechanisms of phonetic encoding by utilizing neurophysiological recordings obtained during neurosurgical procedures. High-density electrode arrays and advanced signal processing will be utilized to unravel both local and population encoding of speech sounds in the lateral temporal cortex. The overall goal is to determine how the brain extracts linguistic elements from a complex acoustic speech signal towards better understanding and remediating human language disorders.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $681,875 )
2024	2024	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	13	7/9/2024	NON-COMPETING CONTINUATION	$681,875
														Subtotal = $681,875

Issue Date FY: 2023 ( Subtotal = $681,938 )
2023	2023	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	001	12	7/24/2023	NON-COMPETING CONTINUATION	$681,938
2023	2023	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	002	12	9/12/2023	NON-COMPETING CONTINUATION	$0
2023	2021	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	10	12/7/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $681,938

Issue Date FY: 2022 ( Subtotal = $682,001 )
2022	2022	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	11	7/14/2022	COMPETING CONTINUATION	$682,001
														Subtotal = $682,001

Issue Date FY: 2021 ( Subtotal = $608,474 )
2021	2021	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	10	7/20/2021	NON-COMPETING CONTINUATION	$608,474
														Subtotal = $608,474

Issue Date FY: 2020 ( Subtotal = $625,689 )
2020	2020	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	9	7/28/2020	NON-COMPETING CONTINUATION	$625,689
														Subtotal = $625,689

Issue Date FY: 2019 ( Subtotal = $714,506 )
2019	2019	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	001	8	7/25/2019	NON-COMPETING CONTINUATION	$707,692
2019	2019	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	7	5/10/2019	SUPPLEMENT FOR EXPANSION	$6,814
														Subtotal = $714,506

Issue Date FY: 2018 ( Subtotal = $661,448 )
2018	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	001	7	7/13/2018	NON-COMPETING CONTINUATION	$661,448
2018	2016	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	5	11/3/2017	EXTENSION WITH OR WITHOUT FUNDS	$0
														Subtotal = $661,448

Issue Date FY: 2017 ( Subtotal = $666,241 )
2017	2017	UNIVERSITY OF CALIFORNIA, SAN FRANCISCO	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	001	6	7/11/2017	COMPETING CONTINUATION	$666,241
2017	2016	UNIVERSITY OF CALIFORNIA, SAN FRANCISCO	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	5	7/6/2017	EXTENSION WITH OR WITHOUT FUNDS	$0
														Subtotal = $666,241

Issue Date FY: 2016 ( Subtotal = $322,854 )
2016	2016	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	5	3/16/2016	EXTENSION WITH OR WITHOUT FUNDS	$322,854
														Subtotal = $322,854

Issue Date FY: 2015 ( Subtotal = $319,781 )
2015	2015	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	4	3/24/2015	NON-COMPETING CONTINUATION	$319,781
														Subtotal = $319,781

Issue Date FY: 2014 ( Subtotal = $323,167 )
2014	2014	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	3	3/21/2014	NON-COMPETING CONTINUATION	$323,167
														Subtotal = $323,167

Issue Date FY: 2013 ( Subtotal = $307,151 )
2013	2013	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	2	3/29/2013	NON-COMPETING CONTINUATION	$290,985
2013	2013	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	001	2	9/27/2013	NON-COMPETING CONTINUATION	$16,166
														Subtotal = $307,151

Issue Date FY: 2012 ( Subtotal = $323,463 )
2012	2012	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Research Related to Deafness and Communication Disorders	000	1	3/28/2012	NEW	$323,463
														Subtotal = $323,463

Grand Total All Awards = $6,918,588

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Functional organization of the superior temporal gyrus for speech perception

Award Number: R01DC012379

ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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