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Perception of dysarthric speech: An objective model of dysarthric speech evaluation with actionable outcomes

Award Number: R01DC006859
ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Perception of dysarthric speech: An objective model of dysarthric speech evaluation with actionable outcomes - The trained ear of the speech-language pathologist is the gold standard assessment tool for clinical practice in motor speech disorders. However, perceptual judgments are vulnerable to bias and their relationship with estimates of listener intelligibility – the final arbiter of speech goodness – is indeterminate. Interpretable, objective, and robust outcome measures that provide targets for treatment are urgently needed in order to provide more precise care and reliably monitor patient progress. Based on theoretical models of speech perception, in our previous grants we have developed a novel set of outcome measures that provide a multi- dimensional intelligibility profile (MIP) by using custom speech stimuli and a new coding strategy that allows us to capture the types of errors that listeners make when listening to dysarthric speech. This has led to a more complete intelligibility profile that codifies these errors at different levels of granularity, from global to discrete. Simultaneously, we have also developed a computational model for evaluation of dysarthric speech capable of reliably estimating a limited set of intelligibility measures directly from the speech acoustics. To date, both the outcome measures and the objective model have been evaluated on cross-sectional data only. In this renewal application, our principal goal is to evaluate specific hypotheses regarding expected changes in this multidimensional intelligibility profile as a result of different intervention instruction conditions (loud, clear, slow). A secondary goal of the proposal is to further refine our objective model to predict the complete intelligibility profile and to evaluate its ability to detect intelligibility changes within individual speakers. This is critical for clinicians who currently have no objective ways to assess the value of their interventions. With the aim of improving the standard of care through technology, the long-term goal of this proposal is to develop stand-alone objective outcome measures for dysarthria that can provide clinicians with reliable treatment targets. Such applications have the potential to dramatically alter the current standard of care in speech pathology for patients with neurological disease or injury. Furthermore, these applications also have the potential to reduce health disparities by partially automating clinical intervention and providing easier access to these services to those in remote areas or in underdeveloped countries.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$60,976 )
2024	2021	ARIZONA STATE UNIVERSITY	660 S MILL AVENUE STE 204	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	15	2/23/2024	NON-COMPETING CONTINUATION	-$60,976
														Subtotal = -$60,976

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2021	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	15	1/25/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $305,399 )
2021	2021	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	15	1/22/2021	NON-COMPETING CONTINUATION	$305,399
														Subtotal = $305,399

Issue Date FY: 2020 ( Subtotal = $307,097 )
2020	2020	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	001	14	1/22/2020	NON-COMPETING CONTINUATION	$307,097
2020	2019	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	002	13	2/20/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2019	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	13	12/13/2019	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $307,097

Issue Date FY: 2019 ( Subtotal = $517,414 )
2019	2019	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	001	13	8/21/2019	SUPPLEMENT FOR EXPANSION	$208,745
2019	2019	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	13	1/15/2019	NON-COMPETING CONTINUATION	$308,669
														Subtotal = $517,414

Issue Date FY: 2018 ( Subtotal = $310,124 )
2018	2018	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	001	12	4/4/2018	NON-COMPETING CONTINUATION	$31,013
2018	2018	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	12	1/24/2018	NON-COMPETING CONTINUATION	$279,111
														Subtotal = $310,124

Issue Date FY: 2017 ( Subtotal = $305,535 )
2017	2017	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	001	11	2/14/2017	COMPETING CONTINUATION	$311,471
2017	2014	ARIZONA STATE UNIVERSITY	660 S MILL AVE STE 312	TEMPE	AZ	85281	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	10	11/17/2016	NON-COMPETING CONTINUATION	-$5,936
														Subtotal = $305,535

Issue Date FY: 2014 ( Subtotal = $302,331 )
2014	2014	ARIZONA STATE UNIVERSITY	P.O. BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	10	6/18/2014	NON-COMPETING CONTINUATION	$302,331
														Subtotal = $302,331

Issue Date FY: 2013 ( Subtotal = $287,848 )
2013	2013	ARIZONA STATE UNIVERSITY	P.O. BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	9	8/15/2013	NON-COMPETING CONTINUATION	$287,848
														Subtotal = $287,848

Issue Date FY: 2012 ( Subtotal = $389,880 )
2012	2012	ARIZONA STATE UNIVERSITY	P.O. BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	7	10/25/2011	SUPPLEMENT FOR EXPANSION	$43,129
2012	2012	ARIZONA STATE UNIVERSITY	P.O. BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	001	8	6/26/2012	NON-COMPETING CONTINUATION	$346,751
														Subtotal = $389,880

Issue Date FY: 2011 ( Subtotal = $304,231 )
2011	2011	ARIZONA STATE UNIVERSITY	P.O. BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	7	6/16/2011	NON-COMPETING CONTINUATION	$304,231
														Subtotal = $304,231

Issue Date FY: 2010 ( Subtotal = $325,596 )
2010	2010	ARIZONA STATE UNIVERSITY	P.O. BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	6	6/2/2010	COMPETING CONTINUATION	$325,596
2010	2010	ARIZONA STATE UNIVERSITY	BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	001	6	6/22/2010	COMPETING CONTINUATION	$0
														Subtotal = $325,596

Issue Date FY: 2008 ( Subtotal = $285,331 )
2008	2008	ARIZONA STATE UNIVERSITY	BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	5	6/20/2008	NON-COMPETING CONTINUATION	$285,331
														Subtotal = $285,331

Issue Date FY: 2007 ( Subtotal = $289,133 )
2007	2007	ARIZONA STATE UNIVERSITY	BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	4	6/22/2007	NON-COMPETING CONTINUATION	$289,133
														Subtotal = $289,133

Issue Date FY: 2006 ( Subtotal = $297,812 )
2006	2006	ARIZONA STATE UNIVERSITY	BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	3	5/10/2006	NON-COMPETING CONTINUATION	$297,812
														Subtotal = $297,812

Issue Date FY: 2005 ( Subtotal = $305,023 )
2005	2005	ARIZONA STATE UNIVERSITY	BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	2	6/16/2005	NON-COMPETING CONTINUATION	$305,023
														Subtotal = $305,023

Issue Date FY: 2004 ( Subtotal = $305,064 )
2004	2004	ARIZONA STATE UNIVERSITY	BOX 873503	TEMPE	AZ	85287	MARICOPA	USA	Research Related to Deafness and Communication Disorders	000	1	6/21/2004	NEW	$305,064
														Subtotal = $305,064

Grand Total All Awards = $4,776,842

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Perception of dysarthric speech: An objective model of dysarthric speech evaluation with actionable outcomes

Award Number: R01DC006859

ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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