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A network-based, mixed methods study to identify and support multiple overdose responders and inform overdose prevention interventions

Award Number: R01DA057682
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2022
PERIOD OF PERFORMANCE END DATE: 07/31/2027

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A network-based, mixed methods study to identify and support multiple overdose responders and inform overdose prevention interventions - The goal of this proposal is to identify strategies to improve the effectiveness and sustainability of naloxone distribution programs for people who use drugs (PWUD). Research suggests that some PWUD enthusiastically take up the role of “overdose responder”, responding to multiple overdoses over relatively short periods of time. Others, however, respond to few or no overdoses. We seek to determine the factors that influence overdose response behavior, with the goal of identifying intervention targets to improve the overall capacity of PWUD to respond to overdoses. To answer these questions, we propose a longitudinal mixed methods study with 300 PWUDs recruited in Reno, Nevada to address the following aims: 1. Identify the characteristics of OD responders (relative to those who do not carry or do not use the naloxone they have), including substance use behaviors, size and composition of social networks, personal factors, and geographic factors. 2. Qualitatively describe the positive and negative experiences of responding to ODs and identify (a) the support or services needed by PWUDs to sustainably respond to ODs in their communities, and (b) the barriers to response among those who do not respond or stop responding. 3. Assess feasibility and acceptability of interventions to improve sustainability of responders and increase initiation of response behavior among non-responders.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $596,508 )
2025	2025	BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER ED	1664 N VIRGINIA ST # 285	RENO	NV	89557	WASHOE	USA	Drug Use and Addiction Research Programs	000	2	8/12/2025	EXTENSION WITH OR WITHOUT FUNDS	$596,508
														Subtotal = $596,508

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	NEVADA SYSTEM OF HIGHER EDUCATION	1664 N VIRGINIA ST	RENO	NV	89557	WASHOE	USA	Drug Use and Addiction Research Programs	000	1	12/15/2022	NEW	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $2,034,699 )
2022	2022	NEVADA SYSTEM OF HIGHER EDUCATION	1664 N VIRGINIA ST	RENO	NV	89557	WASHOE	USA	Drug Use and Addiction Research Programs	000	1	9/21/2022	NEW	$2,034,699
														Subtotal = $2,034,699

Grand Total All Awards = $2,631,207

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A network-based, mixed methods study to identify and support multiple overdose responders and inform overdose prevention interventions

Award Number: R01DA057682

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2022

PERIOD OF PERFORMANCE END DATE: 07/31/2027

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