Friday, April 26, 2024 4/26/2024

Individualizing pharmacotherapy: A novel optimization strategy to increase smoking cessation in the African American community.

Award Number: R01DA046576
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

View Award Abstract

ABSTRACT/SUMMARY The present application outlines a mentored career development plan to improve Dr. Erica Cruvinel's research skills and support her pursuit of a career as an independent researcher. Research Plan: African American (AA) smokers, who bear a disproportionate share of tobacco-related mortality, are poorly served by the one- shot tobacco treatment approaches that dominate research and clinical practice. The parent grant is examining the efficacy of optimized treatment (OPT), that provides smoking cessation counseling while altering the timing, sequencing, or combining of existing pharmacotherapies to maximize efficacy versus enhanced usual care (UC) treatment for smoking cessation. The central hypothesis is that OPT will result in significantly higher abstinence rates relative to UC. Additional hypotheses are that moderators, such as treatment engagement methods including medication use and counseling attendance will mediate the relationship between treatment and abstinence. Dr. Erica Cruvinel will use data collected from the parent grant to examine the impact of other drugs, including marijuana and opioid use, on counseling engagement, medication utilization, and early tobacco abstinence among study participants. This supplement will provide Dr. Cruvinel with intensive interactions with a veteran research team to develop her overall research skills and help her transition into a productive independent researcher. The proposed project will complement the parent grant moderator analysis to enhance understanding of the effectiveness of the intervention across important study subgroups. Candidate Career Development: Dr. Cruvinel will receive training in the conceptualization, implementation, and analysis of clinical trials. She will deepen her understanding of factors impacting treatment usage and cessation among low income and racial/ethnic minority smokers. She will strengthen her track record of scholarly publications and grants. Supplement support will enable her to launch a mentored research program in tobacco-related health disparities. These activities will fully prepare her for a productive, independent research career. This supplement will cover a 2-year period and includes plans for interactions with the parent grant research team, opportunities to contribute intellectually to the research, strong and supportive mentoring, and a structured career development plan. Dr. Cruvinel will accomplish these activities by becoming part of a leading team of researchers through participation on the parent R01, taking the lead on a sub-project contained within the scope of the parent grant, and through enrollment in formal courses and seminars as well as attendance at national conferences. Her plans include submission of an NIH K-series career development award application prior to the end of the supplement. The current, proposed supplement project will support her K-award application by giving her experience studying treatment adherence and increasing her understanding of important factors that can affect adherence.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = $646,438 )
2022	2022	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	4330 SHAWNEE MISSION PKWY	SHAWNEE MISSION	KS	66205	JOHNSON	USA	Drug Abuse and Addiction Research Programs	000	5	4/13/2022	NON-COMPETING CONTINUATION	$646,438
														Subtotal = $646,438

Issue Date FY: 2021 ( Subtotal = $776,620 )
2021	2021	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	4330 SHAWNEE MISSION PKWY	SHAWNEE MISSION	KS	66205	JOHNSON	USA	Drug Abuse and Addiction Research Programs	001	4	4/29/2021	SUPPLEMENT FOR EXPANSION	$111,996
2021	2021	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	4330 SHAWNEE MISSION PKWY	SHAWNEE MISSION	KS	66205	JOHNSON	USA	Drug Abuse and Addiction Research Programs	000	4	4/26/2021	NON-COMPETING CONTINUATION	$664,624
														Subtotal = $776,620

Issue Date FY: 2020 ( Subtotal = $786,450 )
2020	2020	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	4330 SHAWNEE MISSION PKWY	SHAWNEE MISSION	KS	66205	JOHNSON	USA	Drug Abuse and Addiction Research Programs	001	3	7/2/2020	SUPPLEMENT FOR EXPANSION	$111,996
2020	2020	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	4330 SHAWNEE MISSION PKWY	SHAWNEE MISSION	KS	66205	JOHNSON	USA	Drug Abuse and Addiction Research Programs	000	3	4/7/2020	NON-COMPETING CONTINUATION	$674,454
														Subtotal = $786,450

Issue Date FY: 2019 ( Subtotal = $685,119 )
2019	2019	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	4330 SHAWNEE MISSION PKWY	SHAWNEE MISSION	KS	66205	JOHNSON	USA	Drug Abuse and Addiction Research Programs	000	2	3/28/2019	NON-COMPETING CONTINUATION	$685,119
														Subtotal = $685,119

Issue Date FY: 2018 ( Subtotal = $714,501 )
2018	2018	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	4330 SHAWNEE MISSION PKWY	SHAWNEE MISSION	KS	66205	JOHNSON	USA	Drug Abuse and Addiction Research Programs	000	1	6/11/2018	NEW	$714,501
														Subtotal = $714,501

Grand Total All Awards = $3,609,128

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Individualizing pharmacotherapy: A novel optimization strategy to increase smoking cessation in the African American community.

Award Number: R01DA046576

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer