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Comparison of Substance Use Screeners in Assessing Prescription Drug Abuse and Other Illicit Drug Use among Pregnant Women

Award Number: R01DA041328
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary Over the last 3 decades, use of prescription drugs has increased by more than 60%, and prevalence of prescription drug use among pregnant women is currently estimated around 50%. Children born to women who abuse prescription medications are more likely to be born with neonatal abstinence syndrome, the incidence of which has doubled in the past 5 years. Recent national survey data show that the rate of current illicit drug use is 14.6% among pregnant adolescents, 8.6% among young adults, and 3.2% among adults. The first step in identifying both prescription drug abuse and illicit drug use during pregnancy is screening; however, no specific substance use screener has been recommended for use with pregnant women to identify illicit or prescription drug use. The proposed study will compare and validate three existing substance use screeners - 4 P's Plus, NIDA Quick Screen, and the Substance Use Risk Profile-Pregnancy scale - among at least 500 pregnant women in all three trimesters of pregnancy presenting to two primary care clinics in Baltimore over 1 year. Specific aims are to: (1) conduct validity analyses to determine sensitivity, specificity, usability, and how each scale compares to the others and to the gold standard of urine drug testing in identifying prescription and illicit drug use; (2) determine the impact of clinic population variables (age, race, trimester of pregnancy) on validity of the three substance use screeners; and (3) assess birth outcomes (birth weight, gestational age, head circumference, and NICU admissions) associated with the most widely used prescription drug. The end goal of the study is to determine which screening tool(s) is most effective in identifying prescription drug abuse and illicit drug use among pregnant women, utilizing urine drug testing as the gold standard to designate use and electronic medical records (EMR) as a supplement to identify prescribed drugs. Aim 3 was added to capture the important and relevant associations between the most widely used prescription drug and birth outcomes.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2017	THE EMMES COMPANY LLC	401 N WASHINGTON ST STE 700	ROCKVILLE	MD	20850	MONTGOMERY	USA	Drug Abuse and Addiction Research Programs	000	3	5/23/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $0 )
2020	2018	BATTELLE MEMORIAL INSTITUTE	505 KING AVE	COLUMBUS	OH	43201	FRANKLIN	USA	Drug Abuse and Addiction Research Programs	000	2	4/6/2020	SUPPLEMENT FOR EXPANSION	-$1,846
2020	2017	EMMES COMPANY, LLC, THE	401 N WASHINGTON ST STE 700	ROCKVILLE	MD	20850	MONTGOMERY	USA	Drug Abuse and Addiction Research Programs	001	3	4/6/2020	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,846
														Subtotal = $0

Issue Date FY: 2018 ( Subtotal = $19,964 )
2018	2018	BATTELLE MEMORIAL INSTITUTE	505 KING AVENUE	COLUMBUS	OH	43201	FRANKLIN	USA	Drug Abuse and Addiction Research Programs	000	2	5/2/2018	SUPPLEMENT FOR EXPANSION	$19,964
2018	2017	EMMES CORPORATION, THE	401 N WASHINGTON ST STE 700	ROCKVILLE	MD	20850	MONTGOMERY	USA	Drug Abuse and Addiction Research Programs	002	3	9/7/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$168,983
2018	2017	BATTELLE MEMORIAL INSTITUTE	505 KING AVENUE	COLUMBUS	OH	43201	FRANKLIN	USA	Drug Abuse and Addiction Research Programs	001	2	9/7/2018	NON-COMPETING CONTINUATION	-$168,983
														Subtotal = $19,964

Issue Date FY: 2017 ( Subtotal = $538,946 )
2017	2017	BATTELLE MEMORIAL INSTITUTE	505 KING AVENUE	COLUMBUS	OH	43201	FRANKLIN	USA	Drug Abuse and Addiction Research Programs	000	2	7/27/2017	NON-COMPETING CONTINUATION	$538,946
														Subtotal = $538,946

Issue Date FY: 2016 ( Subtotal = $504,232 )
2016	2016	BATTELLE MEMORIAL INSTITUTE	DEPARTMENT L 998	COLUMBUS	OH	43260	FRANKLIN	USA	Drug Abuse and Addiction Research Programs	000	1	9/9/2016	NEW	$504,232
														Subtotal = $504,232

Grand Total All Awards = $1,063,142

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Comparison of Substance Use Screeners in Assessing Prescription Drug Abuse and Other Illicit Drug Use among Pregnant Women

Award Number: R01DA041328

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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