Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Pilot Feasibility of DESCANSO: Cognitive Behavioral Therapy for Latino Cancer Patients to Treat the Symptom Cluster Depression, Insomnia and Fatigue

Award Number: R01CA294307
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/13/2025
PERIOD OF PERFORMANCE END DATE: 06/30/2026

Group Awards By:

View Award Description

Pilot Feasibility of DESCANSO: Cognitive Behavioral Therapy for Latino Cancer Patients to Treat the Symptom Cluster Depression, Insomnia and Fatigue - PROJECT SUMMARY Symptoms of depressed mood, insomnia, and fatigue (DIF) frequently co-occur in cancer patients and Latinos report higher symptom burden than non-Latino white cancer patients. When cancer patients experience these symptoms as a cluster, they lead to more severe burden and poorer quality of life, than do the symptoms individually. Notably, the onset of one symptom can trigger others in this cluster,6 underscoring the importance of treating initial symptoms (e.g., insomnia/fatigue) to prevent the onset of others (e.g., depressed mood). This proposal aims develop and pilot a CBT intervention, DESCANSO (Depresión/Depression, Cansancio/Fatigue, and Sueño/Sleep; Rest in English) to treat the DIF cluster in Spanish speaking Latino cancer patients. This study will be supported by a strong collaboration of clinics in New York (NY), and Puerto Rico addressing local and national disparities in availability of symptom management interventions. Our overall goal is to adapt, refine and pilot the DESCANSO intervention using the ORBIT model for developing behavioral treatments, and the Ecological Validity Framework for cultural adaptation of interventions. Our specific aims are: 1) Refine (culturally adapting) the intervention (DESCANSO) with CBT strategies to treat insomnia, depression, and fatigue (DESCANSO) in Latino patients; and 2) Determine the feasibility of DESCANSO via telehealth and further refine the intervention. We will conduct an open pilot followed by a randomized feasibility pilot with 100 Latino cancer patients (50 from New York and 50 from Puerto Rico) randomized to two arms: 1) DESCANSO or 2) Enhanced usual care. DESCANSO will be the first culturally adapted symptom management intervention to treat cancer-related depression, insomnia, and fatigue in Spanish speaking Latino patients.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $424,249 )
2026	2026	PONCE MEDICAL SCHOOL FOUNDATION INC	388 CALLE LUIS F SALA	PONCE	PR	00716	PONCE	USA	Cancer Detection and Diagnosis Research	002	2	9/17/2026	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$424,249
2026	2025	SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH	1275 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Cancer Detection and Diagnosis Research	000	1	11/19/2025	NEW	$0
2026	2025	SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH	1275 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Cancer Detection and Diagnosis Research	003	1	9/30/2026	NEW	$0
2026	2025	SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH	1275 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Cancer Detection and Diagnosis Research	001	1	9/10/2026	NEW	$0
														Subtotal = $424,249

Issue Date FY: 2025 ( Subtotal = $403,822 )
2025	2025	SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH	1275 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Cancer Detection and Diagnosis Research	000	1	8/13/2025	NEW	$403,822
														Subtotal = $403,822

Grand Total All Awards = $828,071

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Pilot Feasibility of DESCANSO: Cognitive Behavioral Therapy for Latino Cancer Patients to Treat the Symptom Cluster Depression, Insomnia and Fatigue

Award Number: R01CA294307

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/13/2025

PERIOD OF PERFORMANCE END DATE: 06/30/2026

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer