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Behavioral Intervention to Mitigate Nicotine Addiction in Digital Environments

Award Number: R01CA289552
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/03/2024
PERIOD OF PERFORMANCE END DATE: 03/31/2029

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Behavioral Intervention to Mitigate Nicotine Addiction in Digital Environments - Smoking remains highly prevalent among socioeconomically disadvantaged populations, where nicotine addiction is particularly stubborn despite conventional treatment approaches. This project proposes a behavioral intervention to mitigate nicotine addiction by testing evidence-based strategies within a rigorously recruited sample of smokers. The research focuses on users of flavored combusted tobacco products and aims to evaluate the impact of message characteristics on smoking cessation-related outcomes. A multi-phase approach will be used, beginning with qualitative methods and co-creation workshops to develop message content tailored for digital platforms. These messages will then be evaluated through an eye-tracking study and a discrete choice experiment to quantify how users respond to specific message attributes. Finally, a randomized clinical trial (RCT) will test the effects of these messages on behavioral outcomes among a nationally representative sample of individual tobacco users. The proposed work is an individual-level behavioral intervention designed to improve tobacco education efficacy among participants. By examining how targeted intervention components influence the intention to quit smoking and related cessation behaviors, this project will generate insights that inform clinical practice guidelines for smoking cessation among people who smoke.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $579,317 )
2025	2025	GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION INC	58 EDGEWOOD AVE NE	ATLANTA	GA	30303	FULTON	USA	Cancer Cause and Prevention Research	001	2	6/11/2025	NON-COMPETING CONTINUATION	$57,932
2025	2025	GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION INC	58 EDGEWOOD AVE NE	ATLANTA	GA	30303	FULTON	USA	Cancer Cause and Prevention Research	000	2	3/17/2025	NON-COMPETING CONTINUATION	$521,385
														Subtotal = $579,317

Issue Date FY: 2024 ( Subtotal = $593,747 )
2024	2024	GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION INC	58 EDGEWOOD AVE NE	ATLANTA	GA	30303	FULTON	USA	Cancer Cause and Prevention Research	000	1	4/3/2024	NEW	$593,747
														Subtotal = $593,747

Grand Total All Awards = $1,173,064

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Behavioral Intervention to Mitigate Nicotine Addiction in Digital Environments

Award Number: R01CA289552

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/03/2024

PERIOD OF PERFORMANCE END DATE: 03/31/2029

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