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Assessing efficacy and implementation of an EHR tool to assess heart health among survivors

Award Number: R01CA226078
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/08/2018
PERIOD OF PERFORMANCE END DATE: 07/31/2025

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Assessing efficacy and implementation of an EHR tool to assess heart health among survivors - Project Summary Cardiovascular (CV) disease is a significant competing cause of death for many survivors of common early-stage cancers. Up to 90% of survivors have multiple CV risk factors, and many receive cancer therapies with potentially cardiotoxic side effects. Yet cardiovascular health (CVH) is rarely addressed during routine post-treatment survivorship care. CVH assessment could increase patient and provider awareness of CVH and treatment-related cardiotoxicity risk, and promote CVH and cardiotoxicity management during survivorship care, thereby reducing CV disease and cancer recurrence. Such an assessment may be especially critical for the 20% of survivors who do not have a primary care provider and those who received potentially cardiotoxic treatments. Our electronic subsequently adapted Community usability factors clinical examine cancer research team developed an automated health record (EHR)-based CVH assessment tool, deployed it in a primary care setting, and adapted it for use with cancer survivors. Here we propose to implement and evaluate this tool, called the Automated Heart Health Application (AH-HA), among survivors in the NCI Oncology Research Program (NCORP) network. Evaluations in our pilot indicated high and acceptability among oncology providers and survivors. AH-HA incorporates traditional CV risk and potentially cardiotoxic cancer treatment data, and can be easily implemented into routine practice. Thus, we propose a mixed methods, hybrid effectiveness-implementation study to the effects of the AH-HA tool among survivors of breast, prostate, colorectal, and endometrial who are now in survivorship care.Our central hypothesis is that the AH-HA tool will increase (1) CVH awareness and discussions among patients and oncology providers, (2) appropriate referrals and visits to primary care and cardiology, and (3) CV risk reduction and health promotion activities compared to usual care. We seek to speed translation of the AH-HA tool into practice by simultaneously collecting mixed method process data regarding current and future implementation, guided by the Reach, Efficacy, Adoption, Implementation, and Maintenance (RE-AIM) framework. Our Specific Aims are to: (1) Assess the impact of the AH-HA tool on providers' efforts to discuss CVH, refer survivors to primary care and cardiology, and manage CV risk; (2) Measure the impact of the AH-HA tool on survivors' completed primary care and cardiology visits and CVH; and (3) Examine factors influencing current and future implementation of the AH-HA tool. The results of our proposed study will guide future dissemination efforts, with the ultimate goal of improving CVH among the rapidly growing population of cancer survivors. Use of the established NCORP network is efficient and provides an excellent opportunity to test our intervention in community oncology settings, where most cancer survivors receive care.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = -$58,780 )
2026	2024	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	6	12/8/2025	NON-COMPETING CONTINUATION	-$58,780
														Subtotal = -$58,780

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	6	12/18/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $298,871 )
2024	2024	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	6	12/11/2023	NON-COMPETING CONTINUATION	$283,141
2024	2024	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	001	6	4/23/2024	NON-COMPETING CONTINUATION	$15,730
														Subtotal = $298,871

Issue Date FY: 2023 ( Subtotal = $170,155 )
2023	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	001	5	4/4/2023	NON-COMPETING CONTINUATION	$3,403
2023	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	5	3/16/2023	NON-COMPETING CONTINUATION	$166,752
														Subtotal = $170,155

Issue Date FY: 2022 ( Subtotal = $517,124 )
2022	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	4	12/3/2021	NON-COMPETING CONTINUATION	$474,908
2022	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	001	4	6/7/2022	NON-COMPETING CONTINUATION	$42,216
														Subtotal = $517,124

Issue Date FY: 2021 ( Subtotal = $530,058 )
2021	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	3	11/13/2020	NON-COMPETING CONTINUATION	$503,556
2021	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	001	3	3/15/2021	NON-COMPETING CONTINUATION	$26,502
														Subtotal = $530,058

Issue Date FY: 2020 ( Subtotal = $517,927 )
2020	2020	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	2	11/15/2019	NON-COMPETING CONTINUATION	$466,134
2020	2020	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	001	2	1/13/2020	NON-COMPETING CONTINUATION	$51,793
														Subtotal = $517,927

Issue Date FY: 2019 ( Subtotal = $0 )
2019	2018	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	1	5/29/2019	NEW	$0
														Subtotal = $0

Issue Date FY: 2018 ( Subtotal = $499,843 )
2018	2018	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Cancer Cause and Prevention Research	000	1	6/8/2018	NEW	$499,843
														Subtotal = $499,843

Grand Total All Awards = $2,475,198

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Assessing efficacy and implementation of an EHR tool to assess heart health among survivors

Award Number: R01CA226078

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/08/2018

PERIOD OF PERFORMANCE END DATE: 07/31/2025

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