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Effect of Complementary and Alternative Medicine on Pain Among Inpatients

Award Number: R01AT006518
ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/01/2011
PERIOD OF PERFORMANCE END DATE: 12/31/2016

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Effect of Complementary and Alternative Medicine on Pain Among Inpatients - DESCRIPTION (provided by applicant): Effective and safe pain management is a major health priority for the US healthcare system. Pharmaceutical interventions remain the primary approach to pain management, despite their well documented risk of adverse events, potential for addiction, and adverse impact on recovery if used excessively. Nowhere is this more evident than in the post-operative period where roughly 80% of patients report moderate to severe pain after surgery even after receiving pharmaceutical interventions. In inpatient settings, finding an effective non-pharmacologic intervention to augment narcotic medications would be a significant benefit. National surveys indicate that complementary and alternative medicine (CAM) interventions are currently used by 15% of American hospitals. Most often, these therapies are employed to address specific unmet clinical needs, the most frequent of which is pain. Eleven clinical trials have demonstrated the efficacy of CAM therapies to reduce pain (short- and long-term) in hospitalized patients along with traditional pharmaceutical interventions. Generating additional evidence of the effectiveness of these therapies for pain relief would advance knowledge and potentially affect practice patterns. In a preliminary study, we retrospectively studied 1,837 patients who received CAM therapies at Abbott Northwestern Hospital. We found an average reduction in immediate pain of 56% and roughly 33% reported complete pain relief after the initial CAM visit. We recognize inadequacies of this study that limit both our knowledge of how adjunctive CAM therapies are implemented in hospitals and the effect of various CAM therapies on pain management, which can only be answered with prospective data collection. Using a prospective, observational design, we propose a large scale study to build on this exploratory work. It will document predictors of CAM referral, service delivery, and therapy selection for pain management. It will also examine the impact of CAM therapies as adjuncts to traditional interventions on short and long-term changes in pain across clinical groups in a hospital setting. The setting for this study of CAM is the Penny George Institute for Health and Healing at Abbott Northwestern Hospital. The George Institute is uniquely suited for this work as it is the nation's largest inpatient CAM program serving over 19,000 patients since 2004. The proposed study has 3 aims: 1) quantitatively describe a model for delivering CAM therapies to understand selection of patients and CAM therapies for pain management, 2) examine the effects of selected CAM therapies on immediate change in pain, and 3) examine the effects of selected CAM therapies on duration of pain change. Positive results from this study will assist hospitals in the integration of usual care and CAM therapy for pain reduction. Findings may also drive future research on the cost effectiveness of these therapies for pain management, as well as impact on patient outcomes such as length of stay and use of narcotics.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2020 ( Subtotal = $0 )
2020	2014	ALLINA HEALTH SYSTEM	800 E 28TH ST	MINNEAPOLIS	MN	55407	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	4	10/1/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2017 ( Subtotal = -$2,707 )
2017	2014	ALLINA HEALTH SYSTEM	800 E 28TH ST	MINNEAPOLIS	MN	55407	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	001	4	6/23/2017	NON-COMPETING CONTINUATION	-$2,707
2017	2014	ALLINA HEALTH SYSTEM	800 E 28TH ST	MINNEAPOLIS	MN	55407	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	4	12/21/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = -$2,707

Issue Date FY: 2016 ( Subtotal = $0 )
2016	2014	ALLINA HEALTH SYSTEM	POST OFFICE BOX 43	MINNEAPOLIS	MN	55440	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	4	5/27/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2014 ( Subtotal = $706,280 )
2014	2014	ALLINA HEALTH SYSTEM	POST OFFICE BOX 43	MINNEAPOLIS	MN	55440	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	4	5/16/2014	NON-COMPETING CONTINUATION	$706,280
														Subtotal = $706,280

Issue Date FY: 2013 ( Subtotal = $609,424 )
2013	2013	ALLINA HEALTH SYSTEM	POST OFFICE BOX 43	MINNEAPOLIS	MN	55440	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	3	5/31/2013	NON-COMPETING CONTINUATION	$609,424
														Subtotal = $609,424

Issue Date FY: 2012 ( Subtotal = $673,123 )
2012	2012	ALLINA HEALTH SYSTEM	POST OFFICE BOX 43	MINNEAPOLIS	MN	55440	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	2	6/22/2012	NON-COMPETING CONTINUATION	$612,623
2012	2012	ALLINA HEALTH SYSTEM	POST OFFICE BOX 43	MINNEAPOLIS	MN	55440	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	001	2	8/28/2012	SUPPLEMENT FOR EXPANSION	$60,500
														Subtotal = $673,123

Issue Date FY: 2011 ( Subtotal = $617,404 )
2011	2011	ALLINA HEALTH SYSTEM	POST OFFICE BOX 43	MINNEAPOLIS	MN	55440	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	1	5/31/2011	NEW	$617,404
														Subtotal = $617,404

Grand Total All Awards = $2,603,524

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Effect of Complementary and Alternative Medicine on Pain Among Inpatients

Award Number: R01AT006518

ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/01/2011

PERIOD OF PERFORMANCE END DATE: 12/31/2016

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