Thursday, November 21, 2024 11/21/2024

Molecular basis of antibiotic resilience in Mycobacterium tuberculosis

Award Number: R01AI184469
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Summary We have identified a novel driver of treatment failure in Mycobacterium tuberculosis, termed antibiotic resilience, where the bacteria have improved recovery after antibiotic exposure. Population genomic and genetic studies implicate a novel transcriptional regulatory network in control of antibiotic resilience, which we will dissect through genomically informed structure-function studies and in treatment models.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $848,869 )
2024	2024	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	1	9/4/2024	NEW	$81,912
2024	2024	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	1	5/31/2024	NEW	$766,957
														Subtotal = $848,869

Grand Total All Awards = $848,869

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Molecular basis of antibiotic resilience in Mycobacterium tuberculosis

Award Number: R01AI184469

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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