Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Understand and mitigating the influence of extreme weather events on HIV outcomes: A global investigation

Award Number: R01AI179420
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/2025
PERIOD OF PERFORMANCE END DATE: 07/31/2027

Group Awards By:

View Award Description

Understand and mitigating the influence of extreme weather events on HIV outcomes: A global investigation - Project Summary/Abstract The health challenges arising from extreme weather events (EWEs), such as droughts, floods, and major storms (e.g., hurricanes, typhoons) are increasingly common and severe, threatening to undermine public health progress made over the past century. There is limited evidence on how EWEs affect care outcomes among the 37 million people living with HIV/AIDS (PLWH), particularly in geographic regions most vulnerable to EWEs. Cross-sectional studies have shown both drought and excess rainfall to be associated with higher HIV prevalence. However, very little is known about how EWEs impact short- and long-term HIV care outcomes. Our preliminary analysis of data from 11 sub-Saharan African countries found that extreme rainfall may delay the timely initiation of antiretroviral therapy (ART) and increase loss to follow-up among those newly enrolling in HIV care. Our preliminary qualitative work in Kenya suggests that exposure to drought and flooding adversely affects HIV outcomes through decreased food availability and ART adherence and increased infectious disease incidence. The absence of rigorous longitudinal assessments of the relationships and causal pathways between EWE exposures and HIV care outcomes remains a crucial gap in knowledge and obstacle to intervention development. The global IeDEA cohort collaboration, with >2 million PLWH enrolled in HIV care in 44 countries over a long time horizon (2004-present) provides an unparalleled opportunity to characterize the influence of EWEs on HIV care outcomes across several geographic contexts and sub-populations of PLWH (e.g., those with advanced disease, adolescents, those who are pregnant, etc). The proposed 5-year, mixed methods study will combine high resolution daily data on temperature and rainfall from five publicly available climate datasets with the global IeDEA cohort data from 2004-present to longitudinally assess the impacts of EWEs on HIV care outcomes (timely ART initiation HIV viral load monitoring, and HIV viral suppression) (Aim 1). In Aim 2, we will use a mixed methods approach to explore subgroups of vulnerability and resilience to EWEs among PLWH, mechanisms of impact, and adaptation and mitigation strategies employed in specific communities to inform interventions. In Aim 3, we will create and disseminate a country-level public use climate dataset with geocoded temperature and rainfall data going back to 1984 for ready use by other investigators, program implementers, and policymakers. We expect this novel study to inform climate mitigation and adaptation strategies, and lay the groundwork for the development of other targeted (population and region-specific) interventions to address deleterious health effects of EWEs. Moreover, we expect our study to have significant implications for global health programs, policies, mathematical modelers and funders, creating new health-related applications for climate datasets.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $785,768 )
2025	2025	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	55 W 125TH ST FL 7	NEW YORK	NY	10027	NEW YORK	USA	Allergy and Infectious Diseases Research	001	3	8/29/2025	SUPPLEMENT FOR EXPANSION	$20,072
2025	2025	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	55 W 125TH ST FL 7	NEW YORK	NY	10027	NEW YORK	USA	Allergy and Infectious Diseases Research	000	3	8/26/2025	NON-COMPETING CONTINUATION	$729,545
2025	2025	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	55 W 125TH ST FL 7	NEW YORK	NY	10027	NEW YORK	USA	Allergy and Infectious Diseases Research	002	3	8/29/2025	SUPPLEMENT FOR EXPANSION	$36,151
														Subtotal = $785,768

Issue Date FY: 2024 ( Subtotal = $802,257 )
2024	2024	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	55 W 125TH ST FL 7	NEW YORK	NY	10027	NEW YORK	USA	Allergy and Infectious Diseases Research	000	2	7/23/2024	NON-COMPETING CONTINUATION	$802,257
														Subtotal = $802,257

Issue Date FY: 2023 ( Subtotal = $792,047 )
2023	2023	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	55 WEST 125TH ST FL 7	NEW YORK	NY	10027	NEW YORK	USA	Allergy and Infectious Diseases Research	000	1	8/21/2023	NEW	$792,047
														Subtotal = $792,047

Grand Total All Awards = $2,380,072

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Understand and mitigating the influence of extreme weather events on HIV outcomes: A global investigation

Award Number: R01AI179420

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/2025

PERIOD OF PERFORMANCE END DATE: 07/31/2027

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer