Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III)

Award Number: R01AG082777
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/15/2024
PERIOD OF PERFORMANCE END DATE: 08/31/2029

Group Awards By:

View Award Description

A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III) - PROJECT SUMMARY As many as three in four older adults live with chronic pain; a debilitating condition that affects quality of life and independence. Unfortunately, chronic pain both affects and is affected by low levels of physical activity, excess sustained sedentary time, weight gain, and isolation. Across Stage Ia and Ib pilot trials, we have demonstrated the feasibility, acceptability, and potential benefit of a remote group-mediated behavioral intervention rooted in social cognitive and self-determination theories that targets dietary weight loss via caloric restriction and both increased physical activity and decreased sitting via the accumulation of steps in frequent bouts throughout the day (daylong physical activity). Limitations of previous research include: short duration (12 weeks), small samples (up to 44 participants per study), and the inclusion of heterogeneous pain sites. The primary purpose of this Stage II R01 is to test the efficacy of 6 months of a remotely delivered group-mediated weight loss+daylong movement on daily steps (primary outcome), pain interference (secondary outcome), body weight, pain intensity, quality of life, and key psychosocial antecedents of behavior change in older adults with chronic knee or hip osteoarthritic pain. We will also explore for effects on long-term behavior change over 12 months following the intervention. We propose to randomize low-active older adults with chronic osteoarthritic pain and obesity to the weight loss+daylong physical activity intervention or to an enhanced usual care control. These individuals will receive the same self-monitoring technologies as the intervention condition to account for any effect of basic device provision on activity and diet behavior. The results of this trial will inform future real- world efficacy and effectiveness trials of a package well-suited to broad scale delivery.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,191,952 )
2025	2025	WAKE FOREST UNIVERSITY	1834 WAKE FOREST RD	WINSTON SALEM	NC	27109	FORSYTH	USA	Aging Research	001	2	8/15/2025	NON-COMPETING CONTINUATION	$1,191,952
2025	2024	WAKE FOREST UNIVERSITY	1834 WAKE FOREST RD	WINSTON SALEM	NC	27109	FORSYTH	USA	Aging Research	000	1	5/30/2025	NEW	$0
														Subtotal = $1,191,952

Issue Date FY: 2024 ( Subtotal = $1,308,635 )
2024	2024	WAKE FOREST UNIVERSITY	1834 WAKE FOREST RD	WINSTON SALEM	NC	27109	FORSYTH	USA	Aging Research	000	1	9/11/2024	NEW	$1,308,635
														Subtotal = $1,308,635

Grand Total All Awards = $2,500,587

Top

All Categories

About

Search

Reports

Data Submission

Award Information

A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III)

Award Number: R01AG082777

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/15/2024

PERIOD OF PERFORMANCE END DATE: 08/31/2029

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer