Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

The influence of socioeconomic conditions on the incidence of Alzheimer’s Disease in BWHS

Award Number: R01AG077948
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/01/2022
PERIOD OF PERFORMANCE END DATE: 02/28/2027

Group Awards By:

View Award Description

The influence of socioeconomic conditions on the incidence of Alzheimer’s Disease in BWHS - Alzheimer’s Disease and related dementias (ADRD) are important health problems that affect Black Americans more than many other population sub-groups. Socioeconomic conditions associated with housing, education, employment, health care, and other domains – may drive the constellation of social risk factors and comorbidities that increase the risk of ADRD. The mechanisms and pathways by which socioeconomic conditions contribute to ADRD in Black Americans are as yet largely unexplored. We propose to assess the influence of these conditions as they relate to housing, education, and employment on incidence of ADRD in Black women, a group of Americans at high risk of ADRD. Our study will be based on participants and data from a 26-year follow-up study of 59,000 Black women from across the U.S., the Black Women’s Health Study (BWHS). We will develop a measure of socioeconomic conditions that is more comprehensive than most currently in use and test characteristics of this measure against those of several published measures, at the county and state level. Our new measure will use data on factors that include unemployment, poverty, level of education, and housing; the data needed for its development will be obtained by linking participants’ geocoded addresses from 1995-2021 to appropriate public data sources. We will identify incident cases of ADRD through an already developed and tested method of linkage of BWHS participants aged 65 and older to Medicare data for the years 2008-2022; this will yield an estimated 1,500 incident cases of ADRD in 15,000 to 16,000 BWHS participants. Since enrollment in the BWHS in 1995, the participants have provided information on a large number of health and other factors, which include potential risk factors (e.g., hypertension, diabetes, low level of education) and protective factors (e.g., exercise, social support) for ADRD. Thus, it will be possible to assess the effects of socioeconomic conditions alone on incidence of ADRD as well as the combined effects with other common risk factors through moderation or mediation. Since data have been collected over a period of 26 years in geographic areas across the U.S., it will be possible to assess effects of socioeconomic conditions on ADRD incidence over time and place at the county and state level. Thus, the proposed study will provide new and important information on socioeconomic conditions and risk of ADRD in Black women.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $706,655 )
2026	2026	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Aging Research	002	5	6/5/2026	NON-COMPETING CONTINUATION	$0
2026	2026	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Aging Research	000	5	2/23/2026	NON-COMPETING CONTINUATION	$706,655
2026	2026	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Aging Research	001	5	4/30/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $706,655

Issue Date FY: 2025 ( Subtotal = $687,384 )
2025	2025	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Aging Research	000	4	8/1/2025	NON-COMPETING CONTINUATION	$687,384
														Subtotal = $687,384

Issue Date FY: 2024 ( Subtotal = $741,673 )
2024	2024	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Aging Research	001	3	7/3/2024	NON-COMPETING CONTINUATION	$74,167
2024	2024	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Aging Research	000	3	1/23/2024	NON-COMPETING CONTINUATION	$667,506
														Subtotal = $741,673

Issue Date FY: 2023 ( Subtotal = $749,820 )
2023	2023	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Aging Research	000	2	2/22/2023	NON-COMPETING CONTINUATION	$749,820
														Subtotal = $749,820

Issue Date FY: 2022 ( Subtotal = $799,898 )
2022	2022	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Aging Research	000	1	5/13/2022	NEW	$799,898
														Subtotal = $799,898

Grand Total All Awards = $3,685,430

Top

All Categories

About

Search

Reports

Data Submission

Award Information

The influence of socioeconomic conditions on the incidence of Alzheimer’s Disease in BWHS

Award Number: R01AG077948

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/01/2022

PERIOD OF PERFORMANCE END DATE: 02/28/2027

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer