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Disparities in Patterns of Recurrent Stroke in the Elderly

Award Number: R01AG056628
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2018
PERIOD OF PERFORMANCE END DATE: 04/30/2027

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Disparities in Patterns of Recurrent Stroke in the Elderly - Project Summary/Abstract Stroke is a major public health problem in the United States. It is the fifth leading cause of death and a leading cause of serious disability in adults. There are an estimated 800,000 strokes in the United States each year, with more than 7.6 million stroke survivors. Twenty percent of stroke survivors require institutional care after 3 months and 15%-30% are permanently disabled. Stroke in adults is strongly age dependent, and the rate of adverse outcomes and complications associated with stroke increases with advanced age. Because the United States population is aging, the population at risk for stroke, recurrent stroke events, and other post-stroke outcomes will increase over the coming decades. Its high prevalence, associated deficits, and adverse outcomes impose a large burden on patients, their families, and the healthcare system. Stroke survivors are at high risk of new diseases due to their functional disability, neurological deficits, and pre-existing cardiovascular risk factors and comorbidities. The proposed renewal application builds on the Original R01 (Disparities in Patterns of Recurrent Stroke in the Elderly study) to expand our extensive patient-linked surveillance database to provide invaluable information on patterns and trends of 1-, 5-, and 10-year outcomes after ischemic stroke. We will combine Medicare fee-for-service and Medicare Advantage administrative data for 2017 to 2024 to accomplish the following specific aims: 1) to assess national and county-level rates and trends in 1-year outcomes for Medicare Advantage and fee-for-service beneficiaries with ischemic stroke and describe disparities by sociodemographic factors from 2017 to 2024; 2) to assess 5-year outcomes for Medicare Advantage and fee-for-service beneficiaries with ischemic stroke and describe disparities by sociodemographic factors, clinical characteristics, and geographic location from 2017 to 2024; and 3) to assess 5-year and 10- year outcomes for Medicare fee-for-service beneficiaries with ischemic stroke and describe disparities by sociodemographic factors and region from 2001 to 2024. Clinical practice, public policy, and reimbursement decisions are increasingly informed by data obtained from administrative datasets. The proposed study will be the largest contemporary investigation of recurrent stroke rates, post-stroke events, and long-term follow-up of Medicare beneficiaries hospitalized with ischemic stroke in the United States. Results from this project will identify geographic areas and subgroups that have distinctive health profiles that put them at high risk for adverse outcomes after stroke. Such information will inform care providers, insurers, public health agencies, and policy makers about communities that may derive the greatest benefit from targeted programs and community-based interventions.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $639,845 )
2026	2026	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	000	8	4/8/2026	NON-COMPETING CONTINUATION	$639,845
														Subtotal = $639,845

Issue Date FY: 2025 ( Subtotal = $620,994 )
2025	2025	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	001	7	6/10/2025	NON-COMPETING CONTINUATION	$50,693
2025	2025	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	000	7	3/19/2025	NON-COMPETING CONTINUATION	$570,301
														Subtotal = $620,994

Issue Date FY: 2024 ( Subtotal = $631,389 )
2024	2024	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	002	6	5/23/2024	NON-COMPETING CONTINUATION	$631,389
2024	2023	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	001	5	4/3/2024	COMPETING CONTINUATION	$269
2024	2021	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	000	4	4/3/2024	NON-COMPETING CONTINUATION	-$269
														Subtotal = $631,389

Issue Date FY: 2023 ( Subtotal = $599,912 )
2023	2023	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	002	5	8/31/2023	COMPETING CONTINUATION	$599,912
2023	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	000	4	3/31/2023	NON-COMPETING CONTINUATION	$0
2023	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	001	4	8/23/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $599,912

Issue Date FY: 2021 ( Subtotal = $578,761 )
2021	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	000	4	3/30/2021	NON-COMPETING CONTINUATION	$578,761
														Subtotal = $578,761

Issue Date FY: 2020 ( Subtotal = $596,979 )
2020	2020	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	000	3	4/1/2020	NON-COMPETING CONTINUATION	$596,979
														Subtotal = $596,979

Issue Date FY: 2019 ( Subtotal = $879,736 )
2019	2019	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	001	2	9/19/2019	SUPPLEMENT FOR EXPANSION	$234,500
2019	2019	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	000	2	4/5/2019	NON-COMPETING CONTINUATION	$645,236
														Subtotal = $879,736

Issue Date FY: 2018 ( Subtotal = $1,014,524 )
2018	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	000	1	3/20/2018	NEW	$476,037
2018	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	002	1	9/5/2018	SUPPLEMENT FOR EXPANSION	$429,619
2018	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	004	1	9/25/2018	SUPPLEMENT FOR EXPANSION	$108,868
2018	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	001	1	8/30/2018	NEW	$0
2018	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Aging Research	003	1	9/25/2018	NEW	$0
														Subtotal = $1,014,524

Grand Total All Awards = $5,562,140

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Disparities in Patterns of Recurrent Stroke in the Elderly

Award Number: R01AG056628

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2018

PERIOD OF PERFORMANCE END DATE: 04/30/2027

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