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National Social Life, Health, and Aging Project: Rounds 4.2 and 4.4

Award Number: R01AG043538
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2013
PERIOD OF PERFORMANCE END DATE: 02/28/2027

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National Social Life, Health, and Aging Project: Rounds 4.2 and 4.4 - The National Social Life, Health, and Aging Project (NSHAP) is designed to study the links between social, cognitive, mental, and physical health trajectories among older adults, many of whom will acquire Alzheimer’s disease and Alzheimer’s disease-related dementias (AD/ADRD). Started in 2005–06, NSHAP collects a rich and unique set of data at 5-year intervals, including detailed information on social networks, cognitive function, mental health, clinical diagnoses of physical health and AD/ADRD, medications, biological samples, sensory function, and accelerometer-measured daily activity and sleep. Round 4 (R4) is currently underway and when completed in 2023, will provide updated data on ~3,500 respondents aged 60–100. While NSHAP’s 5-year cadence may be adequate at younger ages, this is less true at older ages, especially among those who are experiencing health declines including onset of AD/ADRD and are thus at higher risk of rapid changes and mortality. We propose to augment NSHAP’s study design so researchers can study this part of the lifecourse in more detail. Specifically, we shall transition a subset of NSHAP respondents identified using data through R4 as being at greater risk of mortality to being followed-up every two years. A smaller, age-matched control group at low risk of mortality will also be included and all Black and Hispanic respondents will be included regardless of age or health status. To maximize the completeness and analytic value of information from respondents in increasingly poor physical and cognitive health, including Alzheimer's disease and Alzheimer’s disease-related dementias, we shall administer interviews with targeted measures to capture recent changes in their social, cognitive, and physical health and well-being, and to obtain spousal, proxy, and informant interviews when needed to enhance respondent data. Further, we propose to add new measures that are culturally attuned to the unique experiences of Black and Hispanic populations. This NSHAP subset and a two-year periodicity will allow the study of the antecedents and consequences of changes in key dimensions of health as they occur more rapidly in people’s final years, including AD/ADRD, daily activity, sleep, frailty, polypharmacy, and social well-being, for (1) those at high risk of mortality as compared to those at lower risk, and for (2) those at high risk who die during the period compared to those at high risk who do not die. This strategy differs from that often taken by studies of end of life in which a group of deceased individuals is studied retrospectively, thereby yielding conclusions conditional on having died.12 In contrast, our approach will allow researchers to make conclusions about the future for those currently alive, including onset and course of AD/ADRD, as well as permit us to refine our mortality prediction models. We test the overarching hypothesis that social well-being will modulate mortality risk. Throughout, we test competing hypotheses in which changes in social well-being precede changes in other health indicators such as Alzheimer’s disease and Alzheimer’s disease-related dementias that predispose toward early mortality.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,484,689 )
2025	2025	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST	CHICAGO	IL	60603	COOK	USA	Aging Research	001	13	6/13/2025	NON-COMPETING CONTINUATION	$121,198
2025	2025	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST	CHICAGO	IL	60603	COOK	USA	Aging Research	000	13	4/9/2025	NON-COMPETING CONTINUATION	$1,363,491
														Subtotal = $1,484,689

Issue Date FY: 2024 ( Subtotal = $3,061,230 )
2024	2024	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST	CHICAGO	IL	60603	COOK	USA	Aging Research	000	12	4/17/2024	NON-COMPETING CONTINUATION	$3,061,230
2024	2023	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST	CHICAGO	IL	60603	COOK	USA	Aging Research	003	11	9/10/2024	COMPETING CONTINUATION	$472,756
2024	2022	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST	CHICAGO	IL	60603	COOK	USA	Aging Research	001	10	9/10/2024	NON-COMPETING CONTINUATION	-$400,645
2024	2022	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST	CHICAGO	IL	60603	COOK	USA	Aging Research	002	10	9/10/2024	SUPPLEMENT FOR EXPANSION	-$72,111
														Subtotal = $3,061,230

Issue Date FY: 2023 ( Subtotal = $1,973,143 )
2023	2023	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST 30TH FL	CHICAGO	IL	60603	COOK	USA	Aging Research	002	11	5/31/2023	COMPETING CONTINUATION	$1,973,143
2023	2022	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST 30TH FL	CHICAGO	IL	60603	COOK	USA	Aging Research	001	10	5/24/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2022	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST 30TH FL	CHICAGO	IL	60603	COOK	USA	Aging Research	000	10	5/24/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,973,143

Issue Date FY: 2022 ( Subtotal = $2,468,197 )
2022	2022	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST 30TH FL	CHICAGO	IL	60603	COOK	USA	Aging Research	000	10	4/7/2022	NON-COMPETING CONTINUATION	$2,091,713
2022	2022	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST 30TH FL	CHICAGO	IL	60603	COOK	USA	Aging Research	001	10	5/12/2022	SUPPLEMENT FOR EXPANSION	$376,484
														Subtotal = $2,468,197

Issue Date FY: 2021 ( Subtotal = $5,298,004 )
2021	2021	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST 30TH FL	CHICAGO	IL	60603	COOK	USA	Aging Research	000	9	4/8/2021	NON-COMPETING CONTINUATION	$5,298,004
														Subtotal = $5,298,004

Issue Date FY: 2020 ( Subtotal = $7,562,016 )
2020	2020	NATIONAL OPINION RESEARCH CENTER	55 E MONROE ST 30TH FL	CHICAGO	IL	60603	COOK	USA	Aging Research	001	8	9/14/2020	SUPPLEMENT FOR EXPANSION	$480,339
2020	2020	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	000	8	2/14/2020	NON-COMPETING CONTINUATION	$7,081,677
														Subtotal = $7,562,016

Issue Date FY: 2019 ( Subtotal = $3,637,852 )
2019	2019	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	003	7	9/23/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2019	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	002	7	9/10/2019	SUPPLEMENT FOR EXPANSION	$41,842
2019	2019	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	000	7	3/23/2019	NON-COMPETING CONTINUATION	$3,596,010
2019	2017	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	001	5	5/9/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,637,852

Issue Date FY: 2018 ( Subtotal = $2,066,157 )
2018	2018	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	000	6	7/3/2018	COMPETING CONTINUATION	$2,066,157
														Subtotal = $2,066,157

Issue Date FY: 2017 ( Subtotal = $2,111,671 )
2017	2017	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	002	5	6/30/2017	NON-COMPETING CONTINUATION	$2,111,671
2017	2016	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	001	4	11/14/2016	EXTENSION WITH OR WITHOUT FUNDS	$135,141
2017	2015	NATIONAL OPINION RESEARCH CENTER	1155 E 60TH ST	CHICAGO	IL	60637	COOK	USA	Aging Research	000	3	11/14/2016	NON-COMPETING CONTINUATION	-$135,141
														Subtotal = $2,111,671

Issue Date FY: 2016 ( Subtotal = $2,242,266 )
2016	2016	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	000	4	7/27/2016	EXTENSION WITH OR WITHOUT FUNDS	$2,242,266
														Subtotal = $2,242,266

Issue Date FY: 2015 ( Subtotal = $2,224,061 )
2015	2015	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	000	3	6/8/2015	NON-COMPETING CONTINUATION	$2,224,061
														Subtotal = $2,224,061

Issue Date FY: 2014 ( Subtotal = $2,462,546 )
2014	2014	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	001	2	9/20/2014	NON-COMPETING CONTINUATION	$2,462,546
2014	2013	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	000	1	7/14/2014	NEW	$0
2014	2013	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	002	1	9/21/2014	NEW	$0
2014	2013	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	003	1	9/22/2014	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $2,462,546

Issue Date FY: 2013 ( Subtotal = $2,815,969 )
2013	2013	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	002	1	9/25/2013	SUPPLEMENT FOR EXPANSION	$101,000
2013	2013	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	000	1	8/28/2013	NEW	$2,564,969
2013	2013	NATIONAL OPINION RESEARCH CENTER	1165 EAST 60TH STREET	CHICAGO	IL	60637	COOK	USA	Aging Research	001	1	9/23/2013	SUPPLEMENT FOR EXPANSION	$150,000
														Subtotal = $2,815,969

Grand Total All Awards = $39,407,801

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National Social Life, Health, and Aging Project: Rounds 4.2 and 4.4

Award Number: R01AG043538

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2013

PERIOD OF PERFORMANCE END DATE: 02/28/2027

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