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Personality and Health: A Longitudinal Study

Award Number: R01AG020048
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/20/1997
PERIOD OF PERFORMANCE END DATE: 10/31/2023

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Personality and Health: A Longitudinal Study - Project Summary An increasing number of people are exposed to age graded cognitive declines that develop into mild cognitive impairment and Alzheimer's disease. Individuals vary in the time of onset, and the rate of decline in cognitive functioning associated with these risks. A portion of this variation can be captured by the influence of personality on health over the lifespan. Our overarching aim for this competing renewal is to study associations between personality and cognitive resilience using lifespan personality, health, and health behavior data over the lifespan, in the Hawaii Personality and Health Cohort. This multiethnic cohort provides a rare opportunity to investigate personality processes in relation to cognitive resilience. The study began over 50 years ago with personality assessments of the participants when they were elementary school children. Since 1998, we have located and recruited participants for questionnaire assessments of personality and many other psychosocial variables, and conducted an extensive baseline medical and psychological examination at mean age 50. Using these data, we have demonstrated associations between childhood personality and subjective and objective health outcomes at midlife. A ten-year follow-up examination at age 60 is nearly complete for half of the sample. In this next planned phase of the project, the primary activity will be to complete the follow-up medical and psychological examination of our sample at mean age 60, approximately 10 years after the baseline examination, on all eligible participants (N = 400). Childhood personality and personality change (from childhood to adulthood, plus personality change in adulthood) will be used to predict risk of cognitive impairment at mean age 60, and changes in cognitive functioning assessed annually over a span of four years. We will additionally study change in physical health and cognitive functioning from mean age 50 to 60 using a variety of health indicators and measures. Furthermore, we will examine the main mechanisms thought to account for associations between personality and resilience to cognitive declines, and we shall do so uniquely in the context of a longitudinal study spanning over 5-decades. These mechanisms are based on behavioral (diet, exercise, tobacco and alcohol use, sun exposure) and biological (telomere length, mitochondrial functioning, oxidative stress, biological age) processes which have been hypothesized to underlie associations between personality and resilience to cognitive impairment. This project will generate evidence to guide personality based interventions, in particular by suggesting which traits and trait mechanisms are most relevant in childhood and at midlife (e.g., trait conscientiousness in elementary school, health-behavior mechanisms at midlife). In addition, this project addresses the gross under-representation of Asian-Americans and those of Native-Hawaiian or other Pacific Islander ancestry in health-related scientific research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$6 )
2024	2021	OREGON RESEARCH INSTITUTE	3800 SPORTS WAY	SPRINGFIELD	OR	97477	LANE	USA	Aging Research	000	24	3/11/2024	NON-COMPETING CONTINUATION	-$6
														Subtotal = -$6

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2021	OREGON RESEARCH INSTITUTE	3800 SPORTS WAY	SPRINGFIELD	OR	97477	LANE	USA	Aging Research	000	24	3/27/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $1,437,779 )
2021	2021	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	000	24	4/2/2021	NON-COMPETING CONTINUATION	$1,437,779
														Subtotal = $1,437,779

Issue Date FY: 2020 ( Subtotal = $1,291,553 )
2020	2020	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	000	23	4/8/2020	NON-COMPETING CONTINUATION	$1,291,553
														Subtotal = $1,291,553

Issue Date FY: 2019 ( Subtotal = $1,268,115 )
2019	2019	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	000	22	3/30/2019	NON-COMPETING CONTINUATION	$1,268,115
														Subtotal = $1,268,115

Issue Date FY: 2018 ( Subtotal = $1,361,616 )
2018	2018	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	003	21	5/2/2018	NON-COMPETING CONTINUATION	$0
2018	2018	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	002	21	4/17/2018	NON-COMPETING CONTINUATION	$1,361,616
2018	2017	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	001	20	2/9/2018	COMPETING CONTINUATION	$171,205
2018	2016	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	000	19	2/9/2018	EXTENSION WITH OR WITHOUT FUNDS	-$171,205
														Subtotal = $1,361,616

Issue Date FY: 2017 ( Subtotal = $1,378,165 )
2017	2017	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	001	20	8/16/2017	COMPETING CONTINUATION	$1,378,165
2017	2016	OREGON RESEARCH INSTITUTE	1776 MILLRACE DR	EUGENE	OR	97403	LANE	USA	Aging Research	000	19	8/14/2017	EXTENSION WITH OR WITHOUT FUNDS	$0
														Subtotal = $1,378,165

Issue Date FY: 2016 ( Subtotal = $731,287 )
2016	2016	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	19	5/25/2016	EXTENSION WITH OR WITHOUT FUNDS	$731,287
														Subtotal = $731,287

Issue Date FY: 2015 ( Subtotal = $832,095 )
2015	2015	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	18	5/18/2015	NON-COMPETING CONTINUATION	$752,418
2015	2015	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	001	18	6/12/2015	SUPPLEMENT FOR EXPANSION	$79,677
														Subtotal = $832,095

Issue Date FY: 2014 ( Subtotal = $806,617 )
2014	2014	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	17	5/20/2014	NON-COMPETING CONTINUATION	$806,617
														Subtotal = $806,617

Issue Date FY: 2013 ( Subtotal = $788,253 )
2013	2013	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	16	8/19/2013	NON-COMPETING CONTINUATION	$788,253
														Subtotal = $788,253

Issue Date FY: 2012 ( Subtotal = $737,782 )
2012	2012	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	15	8/6/2012	COMPETING CONTINUATION	$737,782
														Subtotal = $737,782

Issue Date FY: 2011 ( Subtotal = $598,383 )
2011	2011	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	14	8/11/2011	NON-COMPETING CONTINUATION	$598,383
														Subtotal = $598,383

Issue Date FY: 2010 ( Subtotal = $669,761 )
2010	2010	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	001	13	8/18/2010	SUPPLEMENT FOR EXPANSION	$48,382
2010	2010	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	13	7/28/2010	NON-COMPETING CONTINUATION	$621,379
														Subtotal = $669,761

Issue Date FY: 2009 ( Subtotal = $626,366 )
2009	2009	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	12	8/4/2009	NON-COMPETING CONTINUATION	$620,199
2009	2009	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	001	12	9/3/2009	NON-COMPETING CONTINUATION	$6,167
														Subtotal = $626,366

Issue Date FY: 2008 ( Subtotal = $619,524 )
2008	2008	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	11	8/6/2008	NON-COMPETING CONTINUATION	$619,524
														Subtotal = $619,524

Issue Date FY: 2007 ( Subtotal = $644,842 )
2007	2007	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	10	8/27/2007	COMPETING CONTINUATION	$644,842
														Subtotal = $644,842

Issue Date FY: 2006 ( Subtotal = $475,270 )
2006	2006	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	9	7/20/2006	NON-COMPETING CONTINUATION	$475,270
														Subtotal = $475,270

Issue Date FY: 2005 ( Subtotal = $561,565 )
2005	2005	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	8	8/29/2005	NON-COMPETING CONTINUATION	$561,565
														Subtotal = $561,565

Issue Date FY: 2004 ( Subtotal = $607,175 )
2004	2004	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	001	7	9/24/2004	SUPPLEMENT FOR EXPANSION	$49,580
2004	2004	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	7	9/1/2004	NON-COMPETING CONTINUATION	$557,595
														Subtotal = $607,175

Issue Date FY: 2003 ( Subtotal = $546,943 )
2003	2003	OREGON RESEARCH INSTITUTE	1715 FRANKLIN BLVD	EUGENE	OR	97403	LANE	USA	Aging Research	000	6	7/15/2003	NON-COMPETING CONTINUATION	$546,943
														Subtotal = $546,943

Grand Total All Awards = $16,446,101

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Personality and Health: A Longitudinal Study

Award Number: R01AG020048

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/20/1997

PERIOD OF PERFORMANCE END DATE: 10/31/2023

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