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Tailored Adaptive Mobile Messaging to Reduce Problem Drinking

Award Number: R01AA025058
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/12/2017
PERIOD OF PERFORMANCE END DATE: 05/31/2023

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Tailored Adaptive Mobile Messaging to Reduce Problem Drinking - Project Summary The proposed R01, entitled, Tailored Adaptive Mobile Messaging to Reduce Problem Drinking, is submitted to expand on our recently completed R34 grant entitled, Tailored Mobile Messaging to Reduce Problem Drinking (R34AA021502). Despite significant consequences, heavy drinking individuals with non abstinence goals rarely seek treatment. Newer methods such as internet screening and mobile apps provide opportunities to engage and treat this difficult to reach population. We recently completed an R34 study where we developed the first automated comprehensive tailored adaptive (TA) text messaging intervention for problem drinking (PD). We compared TA to different types of automated once a day messaging including: baseline tailored only messaging (TO), loss framed messaging (LF), gain frame messaging (GF), and weekly mobile assessment only (MA). This was done over 12 weeks in a sample of 171 problem drinkers recruited on the internet across the US. All messaging groups outperformed MA on most drinking outcomes, and the TA group had the largest effect sizes on every drinking outcome with an average weekly drink reduction of 9 standard drinks and a reduction of 2 heavy drinking days a week at week 12. Over an 8- month period, 1149 individuals took the web-based screening survey, highlighting the demand for messaging in this population. This study provides initial evidence of the effectiveness of messaging to reduce PD in help-seeking adults across the country. Large scale randomized controlled trials are needed to provide the necessary empirical evidence to validate SMS interventions and to understand moderators of outcome for help seeking heavy drinkers. In a large scale R01 trial, we propose to compare the Tailored Adaptive messaging group (TA; N=300) to the baseline Tailored Only group (TO; N=300) and the weekly Mobile Assessment only group (MA; N=300). All groups will receive messages for a six month period. Participants will complete self-report web-based assessments at Baseline, 1-Month, 3-Months, 6-Months, 12-Months and 18-Months. Participants across conditions will receive weekly MA for 26 weeks. We hypothesize that TA will be superior to MA on all drinking measures at all time periods and TA will outperform TO at all time periods except one month follow-up. Other aims include testing baseline moderators such as alcohol severity and mediators such as message relevance. Overall, if study aims are achieved, we will: 1) have empirical support that TA is an effective intervention for PD and its effects are durable over time; 2) understand whether receiving baseline only tailoring is sufficient or if adaptive tailoring is needed for long-term behavior change; 3) understand the moderators and mediators of outcome in messaging interventions for PD; and 4) be able to disseminate an empirically-supported direct to consumer mobile intervention for PD to anyone with a mobile phone who is not ready to seek in-person care.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2021	PARTNERSHIP TO END ADDICTION	711 3RD AVE RM 500	NEW YORK	NY	10017	NEW YORK	USA	Alcohol Research Programs	000	5	11/8/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $262,526 )
2021	2021	PARTNERSHIP TO END ADDICTION	485 LEXINGTON AVE STE 300	NEW YORK	NY	10017	NEW YORK	USA	Alcohol Research Programs	000	5	6/17/2021	NON-COMPETING CONTINUATION	$262,526
														Subtotal = $262,526

Issue Date FY: 2020 ( Subtotal = $360,801 )
2020	2020	NATIONAL CENTER ON ADDICTION AND SUBSTANCE ABUSE, THE	485 LEXINGTON AVE RM 300	NEW YORK	NY	10017	NEW YORK	USA	Alcohol Research Programs	004	4	6/17/2020	NON-COMPETING CONTINUATION	$360,801
2020	2019	NATIONAL CENTER ON ADDICTION AND SUBSTANCE ABUSE, THE	633 3RD AVE FL 19	NEW YORK	NY	10017	NEW YORK	USA	Alcohol Research Programs	000	3	11/1/2019	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2020	2019	PARTNERSHIP TO END ADDICTION	485 LEXINGTON AVE STE 300	NEW YORK	NY	10017	NEW YORK	USA	Alcohol Research Programs	003	3	11/25/2019	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$512,653
2020	2018	PARTNERSHIP FOR A DRUG-FREE AMERICA, INC.	352 PARK AVE S FL 9	NEW YORK	NY	10010	NEW YORK	USA	Alcohol Research Programs	002	2	11/25/2019	NON-COMPETING CONTINUATION	-$501,759
2020	2017	PARTNERSHIP FOR A DRUG-FREE AMERICA, INC.	352 PARK AVE S FL 9	NEW YORK	NY	10010	NEW YORK	USA	Alcohol Research Programs	001	1	11/25/2019	NEW	-$10,894
														Subtotal = $360,801

Issue Date FY: 2019 ( Subtotal = $500,618 )
2019	2019	NATIONAL CENTER ON ADDICTION AND SUBSTANCE ABUSE, THE	633 3RD AVE FL 19	NEW YORK	NY	10017	NEW YORK	USA	Alcohol Research Programs	001	3	9/20/2019	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$500,618
2019	2018	PARTNERSHIP FOR A DRUG-FREE AMERICA, INC.	352 PARK AVE S FL 9	NEW YORK	NY	10010	NEW YORK	USA	Alcohol Research Programs	000	2	9/20/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $500,618

Issue Date FY: 2018 ( Subtotal = $501,759 )
2018	2018	PARTNERSHIP FOR A DRUG-FREE AMERICA, INC.	352 PARK AVE S FL 9	NEW YORK	NY	10010	NEW YORK	USA	Alcohol Research Programs	000	2	5/10/2018	NON-COMPETING CONTINUATION	$501,759
														Subtotal = $501,759

Issue Date FY: 2017 ( Subtotal = $397,131 )
2017	2017	PARTNERSHIP FOR A DRUG-FREE AMERICA, INC.	352 PARK AVE S FL 9	NEW YORK	NY	10010	NEW YORK	USA	Alcohol Research Programs	000	1	9/11/2017	NEW	$397,131
														Subtotal = $397,131

Grand Total All Awards = $2,022,835

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Tailored Adaptive Mobile Messaging to Reduce Problem Drinking

Award Number: R01AA025058

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/12/2017

PERIOD OF PERFORMANCE END DATE: 05/31/2023

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