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Striatal Mechanisms of Ethanol Seeking

Award Number: R01AA018025
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/01/2013
PERIOD OF PERFORMANCE END DATE: 08/31/2014

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Striatal Mechanisms of Ethanol Seeking - Project Summary/Abstract Habitual behavior does not require an explicit representation of the goal, but is triggered by automatic responses to the stimuli that previously were paired with alcohol reward. The exact time course of this transition has not been defined for alcohol self-administration, however, there are well-defined tests for whether instrumental behavior is goal-directed or habitual that can be used to determine whether or not self-administration is habitual. The current proposal seeks to test the hypothesis that alcohol self-administration after extended training will display the hallmarks of a habitual behavior. As conditioned cues also play a major role in relapse, we will also test the effects of alcohol-predictive cues after extended alcohol self-administration training. The reliance of alcohol-seeking, including that promoted by cues, on dorsal striatal circuitry will be probed.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2014 ( Subtotal = $0 )
2014	2012	ERNEST GALLO CLINIC & RESEARCH CENTER	5858 HORTON STREET, SUITE 200	EMERYVILLE	CA	94608	ALAMEDA	USA	Alcohol Research Programs	000	5	1/27/2014	NON-COMPETING CONTINUATION	-$100,406
2014	2012	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Alcohol Research Programs	001	6	1/27/2014	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$100,406
														Subtotal = $0

Issue Date FY: 2012 ( Subtotal = $337,290 )
2012	2012	ERNEST GALLO CLINIC & RESEARCH CENTER	5858 HORTON STREET, SUITE 200	EMERYVILLE	CA	94608	ALAMEDA	USA	Alcohol Research Programs	000	5	7/25/2012	NON-COMPETING CONTINUATION	$337,290
														Subtotal = $337,290

Issue Date FY: 2011 ( Subtotal = $337,290 )
2011	2011	ERNEST GALLO CLINIC & RESEARCH CENTER	5858 HORTON STREET, SUITE 200	EMERYVILLE	CA	94608	ALAMEDA	USA	Alcohol Research Programs	000	4	8/8/2011	NON-COMPETING CONTINUATION	$337,290
														Subtotal = $337,290

Issue Date FY: 2010 ( Subtotal = $350,906 )
2010	2010	ERNEST GALLO CLINIC & RESEARCH CENTER	5858 HORTON STREET, SUITE 200	EMERYVILLE	CA	94608	ALAMEDA	USA	Alcohol Research Programs	000	3	8/11/2010	NON-COMPETING CONTINUATION	$350,906
														Subtotal = $350,906

Issue Date FY: 2009 ( Subtotal = $347,650 )
2009	2009	ERNEST GALLO CLINIC & RESEARCH CENTER	5858 HORTON STREET, SUITE 200	EMERYVILLE	CA	94608	ALAMEDA	USA	Alcohol Research Programs	000	2	8/19/2009	NON-COMPETING CONTINUATION	$347,650
														Subtotal = $347,650

Issue Date FY: 2008 ( Subtotal = $347,650 )
2008	2008	ERNEST GALLO CLINIC & RESEARCH CENTER	5858 HORTON STREET, SUITE 200	EMERYVILLE	CA	94608	ALAMEDA	USA	Alcohol Research Programs	000	1	9/29/2008	NEW	$347,650
														Subtotal = $347,650

Grand Total All Awards = $1,720,786

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Striatal Mechanisms of Ethanol Seeking

Award Number: R01AA018025

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/01/2013

PERIOD OF PERFORMANCE END DATE: 08/31/2014

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