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Developing a multicomponent lifestyle intervention to address obesity and cardiometabolic risk in Samoan children

Award Number: R00HL166781
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/20/2026
PERIOD OF PERFORMANCE END DATE: 06/30/2029

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Developing a multicomponent lifestyle intervention to address obesity and cardiometabolic risk in Samoan children - PROJECT SUMMARY The goal of the proposed K99/R00 award is to support Dr. Courtney Choy’s development as an independent, community-engaged implementation scientist and epidemiologist focused on the prevention and treatment of noncommunicable, cardiometabolic diseases (CMD). Obesity and cardiometabolic risk are emerging earlier in life than ever before and require urgent preventative interventions. The R00 phase of this award will co-design and pilot test a multicomponent lifestyle intervention to address obesity and CMD risk among children in Samoa, a low-resource population with a large United States (US) diaspora and one of the highest rates of obesity in the world. The K99 phase informed intervention design by identifying several prevention opportunities and demonstrating how modifiable risk factors influence childhood obesity and related CMD risk. Specifically, our data highlight a need for prevention before children reach 9 years old and to encourage healthy dietary behaviors, sufficient sleep, self-efficacy, mental wellness, and positive family relationships. In other settings, routine-based interventions have been effective in addressing these risk behaviors. Therefore, in the R00 phase, we will co-design and test a multicomponent, routine-based intervention to address obesity and CMD risk. The intervention will 1) focus on pre-school aged children, 2) use evidence-based behavior change strategies such as goal setting and positive reinforcement to encourage daily structure and household routines related to healthy eating, physical activity, sleep, and family communication (to support child mental health and parenting self-efficacy), and 3) align with community priorities, needs, and preferences for child health programs. We will assess preliminary efficacy using a hybrid type 1 randomized waitlist-controlled trial among n=40 families. We will evaluate changes in CMD risk behavior and outcomes (glycemic control, weight status, lipids, blood pressure, mental wellness). We will also use an established implementation science framework to examine feasibility, acceptability, and potential for sustainability. We expect to develop a program with the potential for replication in US populations experiencing a high burden of CMDs and comparable low-resource settings. The findings and innovations from this work are applicable to strengthening CMD care in the US.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $249,000 )
2026	2026	UNIVERSITY OF UTAH	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	001	3	8/25/2026	EXTENSION WITH OR WITHOUT FUNDS	$0
2026	2026	UNIVERSITY OF UTAH	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	000	3	8/21/2026	EXTENSION WITH OR WITHOUT FUNDS	$249,000
														Subtotal = $249,000

Grand Total All Awards = $249,000

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Developing a multicomponent lifestyle intervention to address obesity and cardiometabolic risk in Samoan children

Award Number: R00HL166781

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/20/2026

PERIOD OF PERFORMANCE END DATE: 06/30/2029

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