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The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areas

Award Number: P51OD011133
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary There remains an acute, critical need to study HIV/AIDS as approximately 32,000 individuals are infected annually in the U.S. and mortality globally remains at over 630,000 annually. The NIH Office of AIDS has four main priority areas for HIV/AIDS research: reduce the incidence, develop HIV cures, develop next generation therapies and address HIV comorbidities. The National Primate Research Centers are charged with supporting the national needs for nonhuman primate research, with a significant priority on supporting HIV/AIDS related research. The Southwest National Primate Research Center (SNRPC) actively supports research projects in each of the priority areas designated by the Office of AIDS research. There remains a current shortage of Indian origin rhesus macaques in the U.S. due to a ban on exportation and recent global pressures significantly exacerbating the supply. This has led to the increased demand for P51 supported animals to be used to supply HIV/AIDS projects. The SNPRC has been disproportionately affected by the national macaque shortage due to the small size of our SPF rhesus colony and the assumption of a greater responsibility for research using rhesus. The SNPRC resources serve not only a number of internal core scientists that are focused on infectious disease, but also a heavily external-facing research portfolio. The SNPRC supports > 230 active research requests from > 120 affiliated scientists, with >30 % of rhesus macaque projects completed onsite associated with HIV/AIDS related research. These requests have increased the demand for appropriate ABSL2 research holding space in order to support the upcoming HIV/AIDS related projects. This proposed P51 supplement will meet an urgent need to upgrade ABSL2 macaque holding space to support HIV/AIDS related research. Over the last decade several ABSL2 buildings and rooms have been removed from service and taken offline at SNPRC due to failing HVAC systems. This supplement will provide HVAC upgrades to eight ABSL2 rooms to bring them back into service to support rhesus macaque holding at SNPRC.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $7,979,557 )
2024	2024	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	000	26	5/2/2024	NON-COMPETING CONTINUATION	$5,986,845
2024	2024	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	002	26	8/30/2024	SUPPLEMENT FOR EXPANSION	$496,000
2024	2024	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	001	26	5/14/2024	NON-COMPETING CONTINUATION	$1,496,712
														Subtotal = $7,979,557

Issue Date FY: 2023 ( Subtotal = $10,490,304 )
2023	2023	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	001	25	4/20/2023	NON-COMPETING CONTINUATION	$7,483,557
2023	2023	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	002	25	5/1/2023	SUPPLEMENT FOR EXPANSION	$73,260
2023	2023	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Allergy and Infectious Diseases Research	004	25	5/31/2023	SUPPLEMENT FOR EXPANSION	$1,943,312
2023	2023	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	005	25	7/6/2023	SUPPLEMENT FOR EXPANSION	$490,176
2023	2023	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	003	25	5/2/2023	SUPPLEMENT FOR EXPANSION	$499,999
2023	2022	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	000	24	11/8/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $10,490,304

Issue Date FY: 2022 ( Subtotal = $11,233,312 )
2022	2022	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	012	24	8/16/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	009	24	7/13/2022	SUPPLEMENT FOR EXPANSION	$73,260
2022	2022	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	010	24	8/1/2022	SUPPLEMENT FOR EXPANSION	$499,944
2022	2022	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Allergy and Infectious Diseases Research	008	24	6/6/2022	SUPPLEMENT FOR EXPANSION	$2,256,688
2022	2022	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	007	24	6/1/2022	SUPPLEMENT FOR EXPANSION	$419,864
2022	2022	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	005	24	4/29/2022	NON-COMPETING CONTINUATION	$7,483,557
2022	2022	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	011	24	8/3/2022	SUPPLEMENT FOR EXPANSION	$499,999
2022	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	003	23	10/23/2021	COMPETING CONTINUATION	$339,501
2022	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	004	23	11/3/2021	COMPETING CONTINUATION	$0
2022	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Allergy and Infectious Diseases Research	001	23	10/23/2021	SUPPLEMENT FOR EXPANSION	$174,166
2022	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Allergy and Infectious Diseases Research	006	23	6/1/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2020	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	002	22	10/23/2021	SUPPLEMENT FOR EXPANSION	-$339,501
2022	2020	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Allergy and Infectious Diseases Research	000	22	10/23/2021	SUPPLEMENT FOR EXPANSION	-$174,166
														Subtotal = $11,233,312

Issue Date FY: 2021 ( Subtotal = $8,877,641 )
2021	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	003	23	7/1/2021	SUPPLEMENT FOR EXPANSION	$499,742
2021	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	001	23	5/11/2021	COMPETING CONTINUATION	$7,483,557
2021	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Allergy and Infectious Diseases Research	002	23	5/18/2021	SUPPLEMENT FOR EXPANSION	$894,342
2021	2020	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	000	22	1/23/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $8,877,641

Issue Date FY: 2020 ( Subtotal = $10,922,350 )
2020	2020	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	001	22	7/1/2020	SUPPLEMENT FOR EXPANSION	$499,999
2020	2020	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	000	22	4/30/2020	NON-COMPETING CONTINUATION	$7,939,355
2020	2020	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	002	22	7/24/2020	SUPPLEMENT FOR EXPANSION	$482,996
2020	2020	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Allergy and Infectious Diseases Research	003	22	8/21/2020	SUPPLEMENT FOR EXPANSION	$2,000,000
														Subtotal = $10,922,350

Issue Date FY: 2019 ( Subtotal = $9,362,949 )
2019	2019	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	003	21	6/11/2019	SUPPLEMENT FOR EXPANSION	$499,998
2019	2019	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	002	21	5/4/2019	NON-COMPETING CONTINUATION	$7,939,355
2019	2019	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	005	21	8/29/2019	SUPPLEMENT FOR EXPANSION	$499,999
2019	2019	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	006	21	9/18/2019	NON-COMPETING CONTINUATION	$0
2019	2019	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	004	21	7/27/2019	SUPPLEMENT FOR EXPANSION	$423,597
2019	2018	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	001	20	2/22/2019	NON-COMPETING CONTINUATION	$0
2019	2018	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	000	20	11/8/2018	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $9,362,949

Issue Date FY: 2018 ( Subtotal = $8,810,408 )
2018	2018	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	001	20	8/31/2018	SUPPLEMENT FOR EXPANSION	$410,903
2018	2018	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	002	20	9/1/2018	SUPPLEMENT FOR EXPANSION	$460,148
2018	2018	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	000	20	6/18/2018	NON-COMPETING CONTINUATION	$7,939,357
														Subtotal = $8,810,408

Issue Date FY: 2017 ( Subtotal = $7,542,375 )
2017	2017	TEXAS BIOMEDICAL RESEARCH INSTITUTE	7620 NW LOOP 410	SAN ANTONIO	TX	78227	BEXAR	USA	Research Infrastructure Programs	000	19	7/18/2017	NON-COMPETING CONTINUATION	$7,542,375
														Subtotal = $7,542,375

Issue Date FY: 2016 ( Subtotal = $8,379,501 ) (Continued on the next page)
Grand Total All Awards = $114,750,780

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The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areas

Award Number: P51OD011133

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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