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The Implementation Science Center for Cancer Control Equity

Award Number: P50CA244433
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2020
PERIOD OF PERFORMANCE END DATE: 08/31/2024

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The Implementation Science Center for Cancer Control Equity - Abstract - Overall After decades of research developing and testing interventions for cancer control, we have the evidence needed to prevent more than half of all cancers. The impact of these strategies on cancer outcomes is significant for both the general population and low income and under-represented groups that bear a disproportionate share of preventable cancer burden, but evidence-based interventions have not been uniformly used across population groups. Gaps in implementation of the evidence base can be seen for nearly all known cancer prevention and early detection strategies. As a result, we incur substantial avoidable cancer morbidity and mortality and tolerate preventable inequities. The Implementation Science Center for Cancer Control Equity (ISCCCE) will create an ecosystem for robust implementation science (IS) related to cancer prevention and control in Massachusetts community health centers (CHCs) and their local communities. Our theme, improving community health by integrating health equity and implementation science for evidence-based cancer control, reflects our critical mass of expertise in cancer disparities, IS, and community-based cancer prevention and control research. Our “grand challenge” is to address the inequitable implementation and limited scale of evidence-based interventions by developing and testing implementation strategies aimed at narrowing health inequities and by advancing methods that carefully consider the low-resource, complex nature of CHCs where adaptation and cost-effective solutions are needed most. The implementation studies we conduct will address inequities within CHC clinical practice as well as prevention interventions that link to community resources and assets. Our I-Lab is comprised of 31 CHCs who are members of the Mass League of Community Health Centers and use a common EHR vendor- neutral population management system that has extensive reporting capability within and across CHCs, which will allow us to study implementation outcomes in different geographic settings across the state using common measures. Given that achieving equity in community health requires clinical, community, and policy-level interventions, our pilots will also examine how to expand the impact and sustainability of CHCs’ cancer prevention efforts through effective partnerships in community and policy settings. Our Network Unit connects us directly with other Moonshot IS initiatives and national community health leadership, and expands opportunities for collaboration and synergy, building IS capacity in our own institutions and across the nation.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$237,056 )
2025	2022	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	002	3	11/19/2024	SUPPLEMENT FOR EXPANSION	-$27
2025	2022	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	001	3	10/31/2024	SUPPLEMENT FOR EXPANSION	-$44,118
2025	2020	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	000	2	10/18/2024	SUPPLEMENT FOR EXPANSION	-$192,911
														Subtotal = -$237,056

Issue Date FY: 2023 ( Subtotal = $1,087,825 )
2023	2023	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	5	8/7/2023	NON-COMPETING CONTINUATION	$1,087,825
2023	2022	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	000	3	4/11/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2022	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	4	7/12/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,087,825

Issue Date FY: 2022 ( Subtotal = $3,153,820 )
2022	2022	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	002	3	1/13/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	001	3	1/6/2022	SUPPLEMENT FOR EXPANSION	$1,186,970
2022	2022	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Control	007	4	8/30/2022	SUPPLEMENT FOR EXPANSION	$190,280
2022	2022	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	006	4	8/26/2022	NON-COMPETING CONTINUATION	$1,537,320
2022	2021	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	003	3	4/7/2022	NON-COMPETING CONTINUATION	$239,250
2022	2021	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	005	3	7/12/2022	NON-COMPETING CONTINUATION	$0
2022	2021	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	004	3	4/8/2022	NON-COMPETING CONTINUATION	$0
2022	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	000	2	1/6/2022	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $3,153,820

Issue Date FY: 2021 ( Subtotal = $1,408,562 )
2021	2021	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	004	3	9/16/2021	SUPPLEMENT FOR EXPANSION	$205,155
2021	2021	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	3	8/31/2021	NON-COMPETING CONTINUATION	$1,128,762
2021	2021	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	005	3	9/17/2021	SUPPLEMENT FOR EXPANSION	$74,645
2021	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	1	1/27/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	003	2	9/3/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	2	8/3/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,408,562

Issue Date FY: 2020 ( Subtotal = $5,171,617 )
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	002	2	9/24/2020	SUPPLEMENT FOR EXPANSION	$3,432,338
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	1	9/8/2020	SUPPLEMENT FOR EXPANSION	$158,620
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	2	9/3/2020	NON-COMPETING CONTINUATION	$1,580,659
														Subtotal = $5,171,617

Issue Date FY: 2019 ( Subtotal = $1,697,609 )
2019	2019	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	000	1	9/20/2019	NEW	$1,697,609
														Subtotal = $1,697,609

Grand Total All Awards = $12,282,377

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The Implementation Science Center for Cancer Control Equity

Award Number: P50CA244433

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2020

PERIOD OF PERFORMANCE END DATE: 08/31/2024

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