Tuesday, April 23, 2024 4/23/2024

The Pacific Northwest Prostate Cancer SPORE

Award Number: P50CA097186
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

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PROJECT SUMMARY/ABSTRACT The Pacific Northwest (PNW) Prostate Cancer SPORE continuation grant represents a coordinated effort of four institutions with established programs and strengths in translational prostate cancer research including basic, clinical, and population sciences as well as career development: 1) the Fred Hutchinson Cancer Research Center (FHCRC); 2) the University of Washington (UW) and its affiliated institutions; 3) the University of British Columbia and the Prostate Centre of Vancouver General Hospital (UBC); and 4) Oregon Health and Science University (OHSU). These Seattle-, British Columbia- and Portland-based institutions have large multidisciplinary teams of investigators and laboratories dedicated to prostate cancer research and a history of working closely together within this larger milieu. The respective teams of clinicians and researchers at these institutions bring considerable scientific depth, breadth, creativity, and vision required for confronting the most challenging problems blocking progress in our ultimate goal of reducing the morbidity and mortality associated with prostate cancer. This SPORE proposal enlarges the blueprint for a well-built, distinctive and coordinated translational prostate cancer research effort spanning the entire PNW. All participating institutions have made substantial commitments toward supporting the SPORE and its innovative, translational projects: 1) Molecular predictors of prostate cancer progression and mortality; 2) Targeting Emergent Vulnerabilities in AR-Inactive Prostate Cancer; 3) Oncofetal Glycosaminoglycans as Molecular Targets in Prostate Cancer; 4) Clinical Development of Therapeutic Strategies Targeting Damage Repair; and 5) Exploiting mechanisms of response and resistance to next generation androgen pathway antagonists. We also propose four Cores to support these projects: 1) Leadership and administration; 2) Biospecimens; 3) Biostatistics and Data Analytics; and 4) Clinical research. In addition, we propose a Developmental Research Program and a Career Enhancement Program that will significantly embellish and strengthen the translational goals of our prostate cancer research program and expand opportunities for engaging young as well as established investigators in our multidisciplinary environment.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	22	10/13/2023	COMPETING CONTINUATION	$0
2024	2023	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	001	22	10/25/2023	COMPETING CONTINUATION	$0
2024	2023	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	004	22	4/8/2024	COMPETING CONTINUATION	$83,042
2024	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	002	21	3/27/2024	NON-COMPETING CONTINUATION	$0
2024	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	003	21	4/8/2024	NON-COMPETING CONTINUATION	-$83,042
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $2,398,516 )
2023	2023	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	001	22	9/4/2023	COMPETING CONTINUATION	$2,398,516
2023	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	21	5/1/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,398,516

Issue Date FY: 2022 ( Subtotal = $1,950,065 )
2022	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	006	21	9/19/2022	NON-COMPETING CONTINUATION	$1,905,140
2022	2022	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	007	21	9/21/2022	NON-COMPETING CONTINUATION	$44,925
2022	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	005	20	9/15/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2022	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	002	20	8/1/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2022	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	004	20	9/1/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$276,214
2022	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	003	19	9/1/2022	NON-COMPETING CONTINUATION	-$276,214
2022	2021	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	001	20	6/30/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,014,522
2022	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	19	6/30/2022	NON-COMPETING CONTINUATION	-$1,014,522
														Subtotal = $1,950,065

Issue Date FY: 2021 ( Subtotal = $2,075,721 )
2021	2021	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	002	19	9/1/2021	NON-COMPETING CONTINUATION	$2,075,721
2021	2020	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	001	18	4/30/2021	NON-COMPETING CONTINUATION	$0
2021	2020	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	18	1/21/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,075,721

Issue Date FY: 2020 ( Subtotal = $2,074,098 )
2020	2020	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	002	18	8/26/2020	NON-COMPETING CONTINUATION	$2,074,098
2020	2019	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	001	17	5/11/2020	NON-COMPETING CONTINUATION	$0
2020	2019	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	17	11/19/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,074,098

Issue Date FY: 2019 ( Subtotal = $2,095,609 )
2019	2019	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	007	17	9/11/2019	NON-COMPETING CONTINUATION	$2,093,934
2019	2018	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	004	16	3/19/2019	COMPETING CONTINUATION	$0
2019	2018	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	16	1/1/2019	COMPETING CONTINUATION	$0
2019	2018	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	005	16	5/7/2019	COMPETING CONTINUATION	$0
2019	2018	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	002	16	1/25/2019	COMPETING CONTINUATION	$90,044
2019	2018	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	003	16	2/11/2019	COMPETING CONTINUATION	$0
2019	2018	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	006	16	5/31/2019	COMPETING CONTINUATION	$1,675
2019	2017	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	001	15	1/25/2019	NON-COMPETING CONTINUATION	-$90,044
														Subtotal = $2,095,609

Issue Date FY: 2018 ( Subtotal = $2,155,387 )
2018	2018	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	16	9/18/2018	COMPETING CONTINUATION	$2,155,387
														Subtotal = $2,155,387

Issue Date FY: 2017 ( Subtotal = $2,220,197 )
2017	2017	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	003	15	8/17/2017	NON-COMPETING CONTINUATION	$2,105,357
2017	2017	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	004	15	9/20/2017	NON-COMPETING CONTINUATION	$115,000
2017	2016	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	001	14	2/14/2017	EXTENSION WITH OR WITHOUT FUNDS	$657,053
2017	2015	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	13	2/14/2017	NON-COMPETING CONTINUATION	-$657,053
2017	2012	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE N J6-300	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	002	10	5/8/2017	SUPPLEMENT FOR EXPANSION	-$160
														Subtotal = $2,220,197

Issue Date FY: 2016 ( Subtotal = $2,907,960 )
2016	2016	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE NO J6-330	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	001	14	9/14/2016	SUPPLEMENT FOR EXPANSION	$745,961
2016	2016	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE NO J6-330	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	14	8/23/2016	EXTENSION WITH OR WITHOUT FUNDS	$2,161,999
														Subtotal = $2,907,960

Issue Date FY: 2015 ( Subtotal = $2,185,000 )
2015	2015	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE NO J6-330	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	13	9/1/2015	NON-COMPETING CONTINUATION	$2,185,000
														Subtotal = $2,185,000

Issue Date FY: 2014 ( Subtotal = $2,161,845 )
2014	2014	FRED HUTCHINSON CANCER RESEARCH CENTER	1100 FAIRVIEW AVE NO J6-330	SEATTLE	WA	98109	KING	USA	Cancer Centers Support Grants	000	12	8/21/2014	NON-COMPETING CONTINUATION	$2,161,845
														Subtotal = $2,161,845

Grand Total All Awards = $48,770,228

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The Pacific Northwest Prostate Cancer SPORE

Award Number: P50CA097186

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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