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Wake Forest Translational Alcohol Research Center (WF-TARC)

Award Number: P50AA026117
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 12/10/2017
PERIOD OF PERFORMANCE END DATE: 11/30/2027

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Wake Forest Translational Alcohol Research Center (WF-TARC) - WAKE FOREST TRANSLATIONAL ALCOHOL RESEARCH CENTER (WF-TARC) OVERALL SUMMARY The central goal of the Wake Forest Translational Alcohol Research Center (WF-TARC) is to employ integrated, translational animal and human subjects research to study behavioral correlates and neurobiological substrates associated with vulnerability and resilience to alcohol use disorder (AUD). This Center builds on a highly productive translational alcohol research program at WFSM that led to the awarding of this P50 grant in 2017. The WF-TARC is comprised of four research projects and two cores. An administrative core provides the leadership and infrastructure needed to ensure integration across all research projects. This core also provides biostatistical support and promotes interactions and communication between this Center and the many other addiction-related research and educational programs at Wake Forest School of Medicine (WFSM). A pilot project core serves to advance the goals and objectives of the WF-TARC. This core funds projects each year to attract new investigators to bring their talent and expertise to the study of AUD vulnerability. The unifying research focus of the WF-TARC is to leverage the unique strengths and advantages of animal and human subjects research to study behavioral correlates of AUD vulnerability and identify neurobiological adaptations that contribute to this heightened risk of developing this disorder. These studies employ cutting- edge, multidisciplinary experimental approaches spanning molecular, cellular, circuit, and whole-brain analyses. Importantly, studies in each project are also seeking to improve AUD treatment outcomes. The well- integrated conceptual framework and research design facilitates backward and forward interactions across all projects, facilitating the rapid translation of therapeutic discoveries from animals to humans. The WF-TARC leverages a well-established, highly collaborative translational alcohol research program at WFSM and benefits from a strong and growing institutional focus on alcohol and substance use disorders. This Center will continue to enhance the outstanding educational environment at our institution, providing unique training opportunities for the students and postdoctoral who will become the next generation of translational alcohol researchers. Finally, the innovative research supported by the WF-TARC may lead to improved evidence-based therapies for individuals who are at greatest risk of developing AUD, individuals who are particularly ill-served by current AUD treatment options.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,540,337 )
2025	2025	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	001	8	5/14/2025	NON-COMPETING CONTINUATION	$0
2025	2025	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	000	8	11/26/2024	NON-COMPETING CONTINUATION	$1,540,337
														Subtotal = $1,540,337

Issue Date FY: 2024 ( Subtotal = $1,552,610 )
2024	2024	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	002	7	11/30/2023	NON-COMPETING CONTINUATION	$1,552,610
2024	2024	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	003	7	9/4/2024	NON-COMPETING CONTINUATION	$0
2024	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	001	6	11/14/2023	COMPETING CONTINUATION	$985,850
2024	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	000	5	11/14/2023	NON-COMPETING CONTINUATION	-$985,850
														Subtotal = $1,552,610

Issue Date FY: 2023 ( Subtotal = $1,600,290 )
2023	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	000	6	12/30/2022	COMPETING CONTINUATION	$1,600,290
														Subtotal = $1,600,290

Issue Date FY: 2022 ( Subtotal = $1,602,858 )
2022	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	002	5	12/1/2021	NON-COMPETING CONTINUATION	$1,442,573
2022	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	003	5	6/22/2022	NON-COMPETING CONTINUATION	$160,285
2022	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	000	4	11/4/2021	NON-COMPETING CONTINUATION	$0
2022	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	001	4	11/8/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,602,858

Issue Date FY: 2021 ( Subtotal = $1,602,773 )
2021	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	000	4	12/1/2020	NON-COMPETING CONTINUATION	$1,442,497
2021	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	001	4	2/23/2021	NON-COMPETING CONTINUATION	$160,276
2021	2020	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	002	3	4/29/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,602,773

Issue Date FY: 2020 ( Subtotal = $1,987,335 )
2020	2020	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	001	3	8/3/2020	SUPPLEMENT FOR EXPANSION	$384,750
2020	2020	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	000	3	11/27/2019	NON-COMPETING CONTINUATION	$1,602,585
														Subtotal = $1,987,335

Issue Date FY: 2019 ( Subtotal = $1,607,584 )
2019	2019	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	001	2	4/19/2019	NON-COMPETING CONTINUATION	$0
2019	2019	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	000	2	11/30/2018	NON-COMPETING CONTINUATION	$1,607,584
														Subtotal = $1,607,584

Issue Date FY: 2018 ( Subtotal = $1,605,748 )
2018	2018	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Alcohol Research Programs	000	1	12/6/2017	NEW	$1,605,748
														Subtotal = $1,605,748

Grand Total All Awards = $13,099,535

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Wake Forest Translational Alcohol Research Center (WF-TARC)

Award Number: P50AA026117

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 12/10/2017

PERIOD OF PERFORMANCE END DATE: 11/30/2027

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