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C0-Overall: Fetal Ethanol-induced behavior deficits: Mechanisms, diagnosis and Intervention

Award Number: P50AA022534
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/05/2014
PERIOD OF PERFORMANCE END DATE: 06/30/2029

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C0-Overall: Fetal Ethanol-induced behavior deficits: Mechanisms, diagnosis and Intervention - NMARC is a NIAAA-designated Specialized Alcohol Research P50 Center comprised of teams of preclinical and clinical scientists with a history of collaborative research interactions, whose expertise and contributions have synergized the center’s research environment and is facilitating progress towards the achievement of NMARC’s three strategic objectives. These objectives are to: 1) Advance our understanding of how prenatal alcohol exposure (PAE) affects basic neurobiological mechanisms resulting in functional brain damage, which can lead to life-long adverse neurobehavioral consequences. 2) Develop more effective approaches for the diagnosis of individuals with FASD by establishing more sensitive and clinically reliable biomarkers of PAE that are detectable earlier in life, are prognostic of functional brain damage, and could predict long-lasting neurobehavioral consequences in patients with FASD. 3) Develop interventions more effective for PAE-related behavioral deficits. Better interventions may require combinations of neurobehavioral, educational and/or pharmacotherapeutic approaches to ameliorate the often subtle, but long-lasting impact of PAE. NMARC’s prevailing philosophy is that a research center organized to maximize the coordination, communication and synergistic integration across multiple lines of preclinical and clinical investigation provides the best long-term prospect of achieving significant progress towards the dual clinical goals of better diagnosis and interventions that are more effective for patients with FASD. NMARC’s specific aims as an integrated whole during the P50 Phase III will continue to be to: 1) Accelerate progress on each on NMARC’s three strategic objectives. 2) Catalyze the expansion of NMARC’s research capacity and capabilities. 3) Enhance our ability to disseminate knowledge about FASD through seminars, symposia and community outreach activities. 4) Increase the number of undergraduate and graduate students, fellows and residents training in the FASD research field. This competing renewal contains three preclinical and one clinical research components, each consisting of teams of investigators whose projects address one or more of NMARC’s three strategic objectives. Three core components support the research program: 1) A Pilot Project Core of two two-year projects involving faculty investigators new to FASD research. 2) A Scientific Core supporting production of experimental offspring for preclinical projects and recruitment of human subjects for the clinical project, as well as data management and statistical support for all NMARC- affiliated projects. 3) An Administrative Core providing scientific and administrative leadership for the entire NMARC, along with administrative support and budgetary oversight of all NMARC-related activities. The Administrative Core and a Steering Committee are also responsible for ensuring progress towards achieving the Specific Aims of the Center as a whole. Assessment of NMARC’s progress towards the achievement of these aims and the strategic objectives is the responsibility of the Steering Committee, working in conjunction with our external Program Advisory Committee comprised of five renowned alcohol research investigators.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	001	11	2/27/2025	COMPETING CONTINUATION	$355,887
2025	2023	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	10	2/27/2025	NON-COMPETING CONTINUATION	-$355,887
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $1,469,412 )
2024	2024	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	001	11	5/8/2024	COMPETING CONTINUATION	$1,469,412
2024	2023	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	10	5/3/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,469,412

Issue Date FY: 2023 ( Subtotal = $1,482,336 )
2023	2023	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	10	7/3/2023	NON-COMPETING CONTINUATION	$1,482,336
														Subtotal = $1,482,336

Issue Date FY: 2022 ( Subtotal = $1,495,477 )
2022	2022	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	001	9	7/30/2022	NON-COMPETING CONTINUATION	$1,495,477
2022	2021	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	8	3/7/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,495,477

Issue Date FY: 2021 ( Subtotal = $1,495,477 )
2021	2021	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	001	8	6/30/2021	NON-COMPETING CONTINUATION	$1,495,477
2021	2020	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	7	2/3/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,495,477

Issue Date FY: 2020 ( Subtotal = $1,495,477 )
2020	2020	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	002	7	6/30/2020	NON-COMPETING CONTINUATION	$1,495,477
2020	2019	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	001	6	11/25/2019	COMPETING CONTINUATION	$302,733
2020	2018	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	5	11/25/2019	NON-COMPETING CONTINUATION	-$302,733
														Subtotal = $1,495,477

Issue Date FY: 2019 ( Subtotal = $1,508,352 )
2019	2019	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	6	7/18/2019	COMPETING CONTINUATION	$1,508,352
														Subtotal = $1,508,352

Issue Date FY: 2018 ( Subtotal = $1,594,455 )
2018	2018	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	5	6/26/2018	NON-COMPETING CONTINUATION	$1,594,455
														Subtotal = $1,594,455

Issue Date FY: 2017 ( Subtotal = $1,687,249 )
2017	2017	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	4	6/5/2017	NON-COMPETING CONTINUATION	$1,687,249
														Subtotal = $1,687,249

Issue Date FY: 2016 ( Subtotal = $1,723,873 )
2016	2016	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	001	3	8/22/2016	SUPPLEMENT FOR EXPANSION	$61,959
2016	2016	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	3	6/22/2016	NON-COMPETING CONTINUATION	$1,661,914
														Subtotal = $1,723,873

Issue Date FY: 2015 ( Subtotal = $1,604,343 )
2015	2015	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	001	2	9/18/2015	SUPPLEMENT FOR EXPANSION	$75,562
2015	2015	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	2	5/15/2015	NON-COMPETING CONTINUATION	$1,528,781
														Subtotal = $1,604,343

Issue Date FY: 2014 ( Subtotal = $1,618,836 )
2014	2014	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	Alcohol Research Programs	000	1	8/5/2014	NEW	$1,618,836
														Subtotal = $1,618,836

Grand Total All Awards = $17,175,287

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C0-Overall: Fetal Ethanol-induced behavior deficits: Mechanisms, diagnosis and Intervention

Award Number: P50AA022534

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/05/2014

PERIOD OF PERFORMANCE END DATE: 06/30/2029

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