Thursday, November 21, 2024 11/21/2024

Sources, Transport, Exposure & Effects of PFAS (STEEP) Center - RENEWAL

Award Number: P42ES027706
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY/ABSTRACT – OVERALL PFAS have emerged as national priority pollutants, and more than 2000 sites contaminated by PFAS have been identified across the U.S., including 180 EPA-identified Superfund sites. Elevated human exposures to PFAS have been associated with adverse health outcomes, including metabolic disruption, immunotoxicity, and endocrine disruption, although exposure-dependence and individual vulnerability need to be better understood. STEEP II builds on the successful collaborative it established within the first STEEP SRP Center (STEEP I) to further advance the science, training, engagement and outreach in support of SRP mandates. STEEP II will continue to collaborate with the RI and MA state and federal agencies, and will expand its reach to work with DE, ME, NJ, and MI state agencies in support of their needs for knowledge on PFAS. The environmental engineering and chemistry projects will focus on the transport and transformation of PFAS precursors, as well as legacy, novel, and total PFAS. Novel detection tools will be developed and used to support remediation of PFAS- contaminated groundwater, the atmospheric transport and fate of PFAS, and to predict bioaccumulation of PFAS relative to modeling predictions. The Center will build on its leading research on the critical effects of PFAS in children, with a focus on immunotoxicity and metabolism. Given the public health importance of breastfeeding, STEEP II will focus on understanding cellular mechanisms that dictate PFAS uptake and elimination into milk and accumulation in the infant, thereby advancing understanding of toxicokinetic mechanisms and potentials for preventing PFAS from reaching human milk. STEEP II research projects, working with the Community Engagement Core (CEC) and the Data Management and Analysis Core (DMAC), will perform a thorough human exposure assessment for PFAS and risk assessment. STEEP trainees and mentors will remain key to the ongoing growth as a unified Center, via cross-cutting collaboration fostered by the Research Experience and Training Coordination Core (RETCC), and joint mentorship. STEEP II will include an additional focus on Diversity, Equity, and Inclusion (DEI) training for trainees and mentors alike. The STEEP II goals will address the following Specific Aims: Specific Aim 1: Assess the distribution, transformations, and bioaccumulation of PFAS Specific Aim 2: Investigate the processes affecting PFAS distribution and uptake and assess critical adverse effects in humans Specific Aim 3: Engage new and established stakeholders across multiple sites Specific Aim 4: Integrate STEEP internally and execute effective outreach and collaboration with stakeholders


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,544,314 )
2024	2024	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE RD RM 103	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	8	6/21/2024	NON-COMPETING CONTINUATION	$1,544,314
2024	2023	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE RD RM 103	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	7	3/21/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,544,314

Issue Date FY: 2023 ( Subtotal = $1,550,023 )
2023	2023	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	004	7	6/15/2023	NON-COMPETING CONTINUATION	$1,534,273
2023	2023	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	005	7	6/16/2023	SUPPLEMENT FOR EXPANSION	$15,750
2023	2022	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE RD RM 103	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	6	5/12/2023	COMPETING CONTINUATION	$814,601
2023	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE RD RM 103	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	5	5/12/2023	SUPPLEMENT FOR EXPANSION	-$13,896
2023	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE RD RM 103	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	5	5/12/2023	SUPPLEMENT FOR EXPANSION	-$22,476
2023	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE RD RM 103	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	5	5/12/2023	NON-COMPETING CONTINUATION	-$778,229
														Subtotal = $1,550,023

Issue Date FY: 2022 ( Subtotal = $1,925,350 )
2022	2022	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	6	9/13/2022	COMPETING CONTINUATION	$1,909,600
2022	2022	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	6	9/14/2022	SUPPLEMENT FOR EXPANSION	$15,750
2022	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	5	9/7/2022	NON-COMPETING CONTINUATION	$0
2022	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	5	5/2/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,925,350

Issue Date FY: 2021 ( Subtotal = $1,812,126 )
2021	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	5	7/17/2021	SUPPLEMENT FOR EXPANSION	$15,950
2021	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	005	5	8/25/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	004	5	7/30/2021	SUPPLEMENT FOR EXPANSION	$50,000
2021	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	5	3/23/2021	NON-COMPETING CONTINUATION	$1,731,213
2021	2021	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	5	7/19/2021	SUPPLEMENT FOR EXPANSION	$14,963
2021	2020	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	4	11/20/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,812,126

Issue Date FY: 2020 ( Subtotal = $1,576,280 )
2020	2020	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	4	6/30/2020	SUPPLEMENT FOR EXPANSION	$10,800
2020	2020	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	4	4/16/2020	NON-COMPETING CONTINUATION	$1,554,680
2020	2020	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	4	6/30/2020	SUPPLEMENT FOR EXPANSION	$10,800
2020	2019	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	3	3/6/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,576,280

Issue Date FY: 2019 ( Subtotal = $2,658,877 )
2019	2019	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	005	3	9/16/2019	SUPPLEMENT FOR EXPANSION	$378,760
2019	2019	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	3	7/18/2019	SUPPLEMENT FOR EXPANSION	$302,472
2019	2019	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	004	3	8/15/2019	SUPPLEMENT FOR EXPANSION	$400,000
2019	2019	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	3	4/1/2019	NON-COMPETING CONTINUATION	$1,577,645
2019	2018	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	2	12/7/2018	NON-COMPETING CONTINUATION	$0
2019	2018	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	2	6/12/2019	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $2,658,877

Issue Date FY: 2018 ( Subtotal = $1,729,789 )
2018	2018	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	2	9/13/2018	SUPPLEMENT FOR EXPANSION	$119,769
2018	2018	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	2	5/3/2018	SUPPLEMENT FOR EXPANSION	$10,584
2018	2018	UNIVERSITY OF RHODE ISLAND	70 LOWER COLLEGE RD	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	2	3/28/2018	NON-COMPETING CONTINUATION	$1,599,436
														Subtotal = $1,729,789

Issue Date FY: 2017 ( Subtotal = $1,669,877 )
2017	2017	UNIVERSITY OF RHODE ISLAND	75 LOWER COLLEGE RD 110 CARLOTTI BLDG	KINGSTON	RI	02881	WASHINGTON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	1	8/30/2017	NEW	$1,669,877
														Subtotal = $1,669,877

Grand Total All Awards = $14,466,636

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Sources, Transport, Exposure & Effects of PFAS (STEEP) Center - RENEWAL

Award Number: P42ES027706

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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