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Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation

Award Number: P42ES013661
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/12/2006
PERIOD OF PERFORMANCE END DATE: 01/31/2030

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Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation - The Iowa Superfund Research Program (ISRP) is a center of research excellence focused on polychlorinated biphenyls (PCBs). PCBs mixtures called Aroclors were added to thousands of products, including construction materials, until their sales were banned more than 40 years ago. Today, people are still exposed to PCBs indoors and in communities surrounding Superfund sites. Recent ISRP research demonstrated that airborne PCBs present an especially urgent problem: Inhalation of airborne PCBs may be the most significant route for human exposure to these important toxic chemicals. The ISRP’s long-term goal is to develop recommendations to prevent and/or limit human exposure to airborne PCBs and to improve the health and well-being of the population. The ISRP renewal will focus on PCBs in air, particularly in schools and those emitted from contaminated soils and water of Superfund sites. We will examine the health impacts of inhaled PCBs, particularly on adolescents, with a focus on neurodevelopmental and metabolic effects. The ISRP will accomplish its long-term goal through the following integrated Specific Aims: 1) Identify community-supported strategies that address concerns about exposure to airborne PCBs and methods for remediation. We will leverage established and developing partnerships with communities to design and conduct research that responds to community concerns about PCB emissions in Vermont schools and Portland Harbor, Oregon. 2) Determine how lower-chlorinated PCBs cause toxicity during adolescence. We will address how PCBs and their metabolites are risk factors for altered neurodevelopment during adolescence and the mechanisms by which these compounds interfere with lipid metabolism. 3) Reduce airborne PCBs in schools. We will design and test novel sampling methods to directly measure and predict emissions of gas-phase PCBs from building materials in school rooms; distinguish primary, secondary, and tertiary sources; and identify cost-effective strategies to remove or reduce airborne PCBs in schools 4) Define concentrations of airborne PCBs in contaminated water, soil, and sediment and identify mechanisms to reduce their emission. In collaboration with communities in Portland, Oregon, and elsewhere, we will determine the magnitude of emissions from contaminated waters and soils surrounding a Superfund site and evaluate the short-term emissions of PCBs due to sediment dredging. We will also develop novel materials and methods to reduce emissions of PCBs using molecular mechanisms by which microbial populations, including bacteria and fungi, metabolize these compounds in sediments. 5) Train scientists and attract new scientists to environmental health sciences. We will recruit trainees, build on an existing training program offered through the RETCC, and provide trainees and established scientists with new research skills in data science, chemical analysis, community engagement, and research translation.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $2,768,962 )
2025	2025	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	20	6/26/2025	COMPETING CONTINUATION	$0
2025	2025	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	20	6/6/2025	COMPETING CONTINUATION	$0
2025	2025	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	20	5/1/2025	COMPETING CONTINUATION	$2,768,962
2025	2024	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	19	4/23/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,768,962

Issue Date FY: 2024 ( Subtotal = $2,204,080 )
2024	2024	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	19	1/5/2024	NON-COMPETING CONTINUATION	$2,053,367
2024	2024	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	19	9/16/2024	NON-COMPETING CONTINUATION	$150,713
2024	2024	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	19	7/22/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,204,080

Issue Date FY: 2023 ( Subtotal = $2,237,645 )
2023	2023	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	18	6/15/2023	NON-COMPETING CONTINUATION	$0
2023	2023	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	18	1/24/2023	NON-COMPETING CONTINUATION	$2,237,645
														Subtotal = $2,237,645

Issue Date FY: 2022 ( Subtotal = $2,253,095 )
2022	2022	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	17	4/29/2022	NON-COMPETING CONTINUATION	$0
2022	2022	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	17	8/9/2022	SUPPLEMENT FOR EXPANSION	$15,450
2022	2022	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	17	2/1/2022	NON-COMPETING CONTINUATION	$2,237,645
														Subtotal = $2,253,095

Issue Date FY: 2021 ( Subtotal = $2,298,846 )
2021	2021	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	16	2/26/2021	SUPPLEMENT FOR EXPANSION	$50,000
2021	2021	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	16	7/16/2021	SUPPLEMENT FOR EXPANSION	$11,201
2021	2021	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	16	1/28/2021	NON-COMPETING CONTINUATION	$2,237,645
														Subtotal = $2,298,846

Issue Date FY: 2020 ( Subtotal = $2,457,826 )
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	007	15	9/19/2020	COMPETING CONTINUATION	$653,373
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	15	3/31/2020	COMPETING CONTINUATION	$2,447,026
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	004	15	6/29/2020	SUPPLEMENT FOR EXPANSION	$10,800
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	15	4/13/2020	COMPETING CONTINUATION	$0
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	15	4/6/2020	COMPETING CONTINUATION	$0
2020	2019	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	005	14	9/19/2020	NON-COMPETING CONTINUATION	-$237,726
2020	2019	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	14	12/13/2019	NON-COMPETING CONTINUATION	$0
2020	2019	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	006	14	9/19/2020	SUPPLEMENT FOR EXPANSION	-$415,647
														Subtotal = $2,457,826

Issue Date FY: 2019 ( Subtotal = $2,726,226 )
2019	2019	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	14	4/1/2019	NON-COMPETING CONTINUATION	$2,310,579
2019	2019	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	14	9/13/2019	SUPPLEMENT FOR EXPANSION	$415,647
2019	2019	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	14	7/4/2019	NON-COMPETING CONTINUATION	$0
2019	2019	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	004	14	9/19/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2018	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	13	12/7/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,726,226

Issue Date FY: 2018 ( Subtotal = $2,460,602 )
2018	2018	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	13	9/10/2018	SUPPLEMENT FOR EXPANSION	$120,226
2018	2018	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	13	3/23/2018	NON-COMPETING CONTINUATION	$2,340,376
														Subtotal = $2,460,602

Issue Date FY: 2017 ( Subtotal = $2,349,805 )
2017	2017	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	12	6/23/2017	NON-COMPETING CONTINUATION	$190,067
2017	2017	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	12	5/8/2017	SUPPLEMENT FOR EXPANSION	$10,796
2017	2017	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	12	3/17/2017	NON-COMPETING CONTINUATION	$2,138,255
2017	2017	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	12	5/9/2017	SUPPLEMENT FOR EXPANSION	$10,687
														Subtotal = $2,349,805

Issue Date FY: 2016 ( Subtotal = $2,411,778 )
2016	2016	UNIVERSITY OF IOWA	2 GILMORE HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	11	3/25/2016	NON-COMPETING CONTINUATION	$2,411,778
2016	2015	UNIVERSITY OF IOWA	2 GILMORE HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	10	10/22/2015	COMPETING CONTINUATION	$0
2016	2015	UNIVERSITY OF IOWA	2 GILMORE HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	10	1/14/2016	COMPETING CONTINUATION	$0
														Subtotal = $2,411,778

Issue Date FY: 2015 ( Subtotal = $2,489,430 ) (Continued on the next page)
2015	2015	UNIVERSITY OF IOWA	2 GILMORE HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	006	9	9/23/2015	SUPPLEMENT FOR EXPANSION	$0
2015	2015	UNIVERSITY OF IOWA	2 GILMORE HALL	IOWA CITY	IA	52242	JOHNSON	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	9	6/17/2015	SUPPLEMENT FOR EXPANSION	$148,852
Grand Total All Awards = $54,183,421

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Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation

Award Number: P42ES013661

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/12/2006

PERIOD OF PERFORMANCE END DATE: 01/31/2030

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