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GENE ONTOLOGY CONSORTIUM

Award Number: P41HG002273
ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 01/19/2001
PERIOD OF PERFORMANCE END DATE: 02/28/2012

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GENE ONTOLOGY CONSORTIUM - DESCRIPTION (provided by applicant): Our objective is to provide the scientific community with a consistent, robust information environment for describing, sharing, integrating and comparing the functional roles of genes, proteins and functional RNAs within and across all organisms. The Gene Ontology (GO) Consortium is an international collaboration of model organism database and genome annotation groups who have joined together to establish standards for describing genomes and gene products and to provide tools and support for the consistent application of these standards for functional annotations that facilitate and enable biological research. The GO provides specific classifications including well-defined, biologically descriptive terms that are organized into specialization and part-of hierarchies for the domains of genome feature, molecular function, biological process and cellular component. The GO classifications are independent of any particular technology, an uncoupling of terminology from technology that encourages application of these semantic standards by organism annotation groups that utilize a wide range of technical environments. The GO has been widely adopted and used for representation of complex biological information for model organism genomes, and is increasingly used for the functional annotation of emerging genomes. With the increased use of the GO, the Consortium must actively work to ensure both the accuracy of the ontologies as well as consistency and quality of annotations so that these resources may be reliably used to draw inferences and make biological predictions. We will do so by focusing on four key aims: 1) We will maintain logically rigorous and biologically precise ontologies; 2) We will ensure comprehensive annotation of reference genomes, including human, using the GO; 3) We will support GO annotation efforts for emerging genomes and for those specialized sets of genes and proteins of particular community interest; and 4) We will provide annotations and tools to the research community thus supporting experimental biologists, genome informaticists, and computational biologists who are using GO annotations in their research particularly in the areas of functional genomics and comparative biology. The relevance of this work for public health is that comprehensive integration and standardization of biomedical and genomics information is an essential component of advancing the understanding of the molecular systems underlying human health and disease outcomes.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2011 ( Subtotal = $2,923,298 )
2011	2011	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	000	11	3/4/2011	NON-COMPETING CONTINUATION	$2,923,298
														Subtotal = $2,923,298

Issue Date FY: 2010 ( Subtotal = $4,258,406 )
2010	2010	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Recovery Act Research Support	001	10	9/23/2010	SUPPLEMENT FOR EXPANSION	$745,063
2010	2010	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	000	10	4/9/2010	NON-COMPETING CONTINUATION	$3,513,343
														Subtotal = $4,258,406

Issue Date FY: 2009 ( Subtotal = $4,476,310 )
2009	2009	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	003	9	8/19/2009	NON-COMPETING CONTINUATION	$0
2009	2009	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Trans-NIH Recovery Act Research Support	004	9	9/30/2009	SUPPLEMENT FOR EXPANSION	$1,038,804
2009	2009	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	001	9	3/2/2009	NON-COMPETING CONTINUATION	$3,093,756
2009	2009	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	002	9	3/24/2009	NON-COMPETING CONTINUATION	$343,750
2009	2008	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	000	8	11/14/2008	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,476,310

Issue Date FY: 2008 ( Subtotal = $3,301,348 )
2008	2008	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	001	8	5/14/2008	SUPPLEMENT FOR EXPANSION	$36,216
2008	2008	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	000	8	3/4/2008	NON-COMPETING CONTINUATION	$3,030,984
2008	2008	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	002	8	9/22/2008	SUPPLEMENT FOR EXPANSION	$234,148
														Subtotal = $3,301,348

Issue Date FY: 2007 ( Subtotal = $3,146,180 )
2007	2007	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	000	7	2/28/2007	COMPETING CONTINUATION	$3,146,180
														Subtotal = $3,146,180

Issue Date FY: 2006 ( Subtotal = $3,071,397 )
2006	2006	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	000	6	3/20/2006	NON-COMPETING CONTINUATION	$3,071,397
														Subtotal = $3,071,397

Issue Date FY: 2005 ( Subtotal = $3,078,519 )
2005	2005	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	000	5	2/22/2005	NON-COMPETING CONTINUATION	$3,078,519
														Subtotal = $3,078,519

Issue Date FY: 2004 ( Subtotal = $3,100,000 )
2004	2004	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Human Genome Research	000	4	3/5/2004	COMPETING CONTINUATION	$3,100,000
														Subtotal = $3,100,000

Grand Total All Awards = $27,355,458

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GENE ONTOLOGY CONSORTIUM

Award Number: P41HG002273

ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 01/19/2001

PERIOD OF PERFORMANCE END DATE: 02/28/2012

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