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Mobilize Center: Models for Mobile Sensing and Precision Rehabilitation

Award Number: P41EB027060
ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/25/2026
PERIOD OF PERFORMANCE END DATE: 07/31/2031

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Mobilize Center: Models for Mobile Sensing and Precision Rehabilitation - Limited mobility due to conditions like osteoarthritis, neuromuscular diseases, and limb loss affects millions of individuals, at enormous personal and societal cost. The research community has a critical need for tools to rapidly measure and analyze movement to uncover the factors that limit mobility and predict the effects of treatments. These tools must measure movement outside of laboratories and reduce the barriers to participation in research. The Mobilize Center is providing these much needed tools and exerting a substantial, positive influence on the large community of researchers who study mobility limitations. In the Mobilize Center’s next phase we will transform the field by dramatically increasing the quality and quantity of data available about biomechanics, movement, and rehabilitation. We will leverage this data to build digital twins to predict, with unprecedented accuracy, how individuals respond to treatments. We will achieve this vision by accomplishing the following aims: 1. Develop and support the OpenCap software to enable researchers to use smartphones to collect high-quality movement data in minutes, enabling large-scale studies. We will develop algorithms in OpenCap to enable accurate, three-dimensional, muscle-driven simulations of both the lower and upper extremity, further preserve patient privacy, and objectively measure balance. 2. Develop and support the AddBiomechanics software to automatically process, analyze, and share motion capture data. We will add support for drag-and-drop processing of inertial measurement unit (IMU) data, automated tools to clean and curate large-scale movement data, and machine learning models that predict dynamics from kinematics 1,000 times faster than current approaches. 3. Create and validate the next generation of fast and accurate, predictive musculoskeletal simulations by combining biomechanics with machine learning. We will apply modern optimization approaches to create a fast biomechanics simulator and use this simulator to synthesize large-scale data that, together with experimental data, trains accurate and useful machine learning models. We will also create algorithms to predict how individuals respond to assistive exoskeletons and prosthetics—a grand challenge in the field. Through intensive interactions with our Collaborative Projects, we will focus on improving outcomes for individuals with limited mobility due to conditions such as osteoarthritis, neuromuscular diseases, limb loss, and workplace injuries. The Center’s tools and services will enable researchers to revolutionize how we diagnose, monitor, and treat limitations in movement.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $1,594,950 )
2026	2026	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	6	8/25/2026	COMPETING CONTINUATION	$1,595,000
2026	2025	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	3/4/2026	NON-COMPETING CONTINUATION	-$50
														Subtotal = $1,594,950

Issue Date FY: 2025 ( Subtotal = $1,179,632 )
2025	2025	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	5	6/24/2025	NON-COMPETING CONTINUATION	$117,964
2025	2025	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	11/27/2024	NON-COMPETING CONTINUATION	$1,061,668
														Subtotal = $1,179,632

Issue Date FY: 2024 ( Subtotal = $1,179,632 )
2024	2024	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	4	5/7/2024	NON-COMPETING CONTINUATION	$117,964
2024	2024	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	4	11/30/2023	NON-COMPETING CONTINUATION	$1,061,668
														Subtotal = $1,179,632

Issue Date FY: 2023 ( Subtotal = $1,436,232 )
2023	2023	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	3	8/25/2023	SUPPLEMENT FOR EXPANSION	$231,600
2023	2023	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	3	1/31/2023	NON-COMPETING CONTINUATION	$1,204,632
														Subtotal = $1,436,232

Issue Date FY: 2022 ( Subtotal = $1,204,632 )
2022	2022	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	3/1/2022	NON-COMPETING CONTINUATION	$1,084,166
2022	2022	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	2	7/29/2022	NON-COMPETING CONTINUATION	$0
2022	2022	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	4/22/2022	NON-COMPETING CONTINUATION	$120,466
														Subtotal = $1,204,632

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2020	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	1	5/11/2021	NEW	$0
2021	2020	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	3/26/2021	NEW	$0
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $1,504,632 )
2020	2020	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	5/6/2020	NEW	$1,504,632
														Subtotal = $1,504,632

Grand Total All Awards = $8,099,710

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Mobilize Center: Models for Mobile Sensing and Precision Rehabilitation

Award Number: P41EB027060

ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/25/2026

PERIOD OF PERFORMANCE END DATE: 07/31/2031

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