Thursday, November 21, 2024 11/21/2024

Caribbean Primate Research Center Program

Award Number: P40OD012217
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY/ABSTRACT: The major goal of this application is to improve and maintain the Caribbean Primate Research Center's (CPRC) unique research resources through support of operations, administration, veterinary care and research. The CPRC consists of four integrated facilities: (1) Cayo Santiago Biological Field Station (CSBFS), the most valuable of the CPRC research resources that holds a colony of free-ranging rhesus brought from India to Cayo Santiago (CS) in 1938.; (2) the Sabana Seca Field Station (SSFS), the CPRC's headquarters located 10 miles outside of San Juan that houses rhesus monkeys derived from Cayo Santiago colony in various outdoor configurations for biomedical and behavioral studies that are not feasible on free-ranging animals; (3) the Laboratory of Virology and Genetics (LVG), located on the Medical Sciences Campus (MSC), in San Juan which support several research initiatives using rhesus monkeys as a model; and (4) the Laboratory of Primate Morphology (LPM), which is also located on the MSC, and houses the CPRC skeletal collections, unique assemblages of nonhuman primate skeletons for genetic, developmental, pathological and anatomical research. As described in this proposal, CPRC is organized into four complementary and integrated divisions: Primate Resources, Virology and Genetics, Behavior and Neurosciences, and Primate Morphology. In 2020, the unprecedented COVID-19 pandemic added an additional stress to the already tenuous NHP supply by increasing the demand around the world. As a result, the National Primate Research Centers (NPRC), with the support of NIH/ORIPs, launched an initiative to establish the NHP Strategic Reserve (NSR). The CPRC served as a pioneer in support of the NSR in several ways. First, at the onset of the COVID-19 pandemic, the CPRC was able to immediately supply animals to aid COVID- 19 research in the continental US, resulting in numerous high-impact publications. Additionally, in collaboration with ORIP, underscoring the value of the NIH/ORIP-funded resources, and as a step in the NSR development, the CPRC proactively engaged in agreements with some NPRCs and supplied high quality animals to expand their breeding population, as well as to increase their genetic diversity. Funds are requested in this application to maintain CPRC basic infrastructure of Primate Resources, which are used to support numerous research projects locally, national and internationally. This grant will also allow CPRC to continue supporting the Translational Science Initiative (TSI) under the Applied Research Component. A major strength of this TSI is conducting multidisciplinary collaborative studies to establish and validate NHP models for preclinical translational projects related to different human diseases.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,947,914 )
2025	2025	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	38	11/15/2024	NON-COMPETING CONTINUATION	$1,947,914
														Subtotal = $1,947,914

Issue Date FY: 2024 ( Subtotal = $3,950,733 )
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	009	37	7/30/2024	COMPETING CONTINUATION	$0
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Trans-NIH Research Support	002	37	5/3/2024	SUPPLEMENT FOR EXPANSION	$1,016,909
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Trans-NIH Research Support	003	37	5/8/2024	SUPPLEMENT FOR EXPANSION	-$1,016,909
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	001	37	12/8/2023	COMPETING CONTINUATION	$1,874,729
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Trans-NIH Research Support	004	37	5/14/2024	SUPPLEMENT FOR EXPANSION	$1,016,909
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	011	37	9/6/2024	COMPETING CONTINUATION	$0
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Trans-NIH Research Support	010	37	8/12/2024	SUPPLEMENT FOR EXPANSION	$498,932
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	007	37	7/15/2024	COMPETING CONTINUATION	$655,406
2024	2024	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	005	37	6/14/2024	COMPETING CONTINUATION	$560,163
2024	2023	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	008	36	7/15/2024	SUPPLEMENT FOR EXPANSION	-$89,693
2024	2023	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	006	36	7/15/2024	NON-COMPETING CONTINUATION	-$565,713
2024	2023	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	36	11/30/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,950,733

Issue Date FY: 2023 ( Subtotal = $2,735,611 )
2023	2023	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	36	12/10/2022	NON-COMPETING CONTINUATION	$2,125,117
2023	2023	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	001	36	2/23/2023	NON-COMPETING CONTINUATION	$236,124
2023	2023	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	004	36	7/14/2023	NON-COMPETING CONTINUATION	$0
2023	2023	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	003	36	6/15/2023	SUPPLEMENT FOR EXPANSION	$374,370
2023	2021	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	B622 MAIN BUILDING FLR 6	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	002	34	5/17/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $2,735,611

Issue Date FY: 2022 ( Subtotal = $2,361,241 )
2022	2022	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	001	35	5/5/2022	NON-COMPETING CONTINUATION	$236,125
2022	2022	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	35	11/30/2021	NON-COMPETING CONTINUATION	$2,125,116
														Subtotal = $2,361,241

Issue Date FY: 2021 ( Subtotal = $2,601,631 )
2021	2021	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	005	34	6/23/2021	COMPETING CONTINUATION	$956,105
2021	2021	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	002	34	2/25/2021	COMPETING CONTINUATION	$0
2021	2021	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	003	34	3/24/2021	COMPETING CONTINUATION	$338,748
2021	2021	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	007	34	7/7/2021	COMPETING CONTINUATION	$0
2021	2021	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	001	34	2/10/2021	COMPETING CONTINUATION	$2,032,489
2021	2021	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	008	34	8/20/2021	SUPPLEMENT FOR EXPANSION	$230,394
2021	2020	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	006	33	6/23/2021	SUPPLEMENT FOR EXPANSION	-$423,800
2021	2020	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	004	33	6/23/2021	NON-COMPETING CONTINUATION	-$532,305
2021	2020	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	33	2/9/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,601,631

Issue Date FY: 2020 ( Subtotal = $2,682,120 )
2020	2020	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	004	33	9/18/2020	NON-COMPETING CONTINUATION	$0
2020	2020	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	001	33	12/17/2019	NON-COMPETING CONTINUATION	$0
2020	2020	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	003	33	6/5/2020	SUPPLEMENT FOR EXPANSION	$423,800
2020	2020	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	002	33	3/4/2020	NON-COMPETING CONTINUATION	$225,833
2020	2020	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	33	11/14/2019	NON-COMPETING CONTINUATION	$2,032,487
														Subtotal = $2,682,120

Issue Date FY: 2019 ( Subtotal = $2,782,991 )
2019	2019	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	001	32	9/4/2019	SUPPLEMENT FOR EXPANSION	$499,671
2019	2019	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	32	12/22/2018	NON-COMPETING CONTINUATION	$2,283,320
														Subtotal = $2,782,991

Issue Date FY: 2018 ( Subtotal = $2,283,320 )
2018	2018	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	001	31	6/8/2018	NON-COMPETING CONTINUATION	$228,333
2018	2018	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	31	11/30/2017	NON-COMPETING CONTINUATION	$2,054,987
														Subtotal = $2,283,320

Issue Date FY: 2017 ( Subtotal = $2,283,320 )
2017	2017	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	001	30	8/10/2017	NON-COMPETING CONTINUATION	$228,332
2017	2017	UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS	MAIN BLDG FLR 6 B-622	SAN JUAN	PR	00935	SAN JUAN	USA	Research Infrastructure Programs	000	30	11/15/2016	NON-COMPETING CONTINUATION	$2,054,988
														Subtotal = $2,283,320

Issue Date FY: 2016 ( Subtotal = $2,428,977 ) (Continued on the next page)
Grand Total All Awards = $35,024,376

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Caribbean Primate Research Center Program

Award Number: P40OD012217

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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