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Rat Resource and Research Center

Award Number: P40OD011062
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/01/2001
PERIOD OF PERFORMANCE END DATE: 01/31/2026

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Rat Resource and Research Center - Abstract (Overall) The mission of the Rat Resource and Research Center (RRRC) is to provide biomedical investigators with the rat models, embryonic stem cells, related reagents, protocols, information, support and services that will facilitate their research. The RRRC serves as a unique repository by importing, storing and distributing a large number of rat strains/stocks. It assures that valuable models are preserved and made available to interested investigators, allows researchers to satisfy NIH requirements for resource sharing, relieves individual investigators from the burden of animal distribution and ensures that models are maintained with rigorous genetic quality control and health monitoring to promote experimental rigor and reproducibility. Recent advances in genome editing technologies are facilitating the ability to perform sophisticated genetic modifications in rats in order to study both normal biological processes and disease states. As a result, the number of rat models and the number of investigators using rat models for biomedical research is increasing and the RRRC, as one of the only centralized repositories in the world will continue to serve a critical role for archiving and distributing these new models. To improve repository functions, applied research to optimize methods for sperm cryopreservation and in vitro fertilization in the rat will be undertaken and ongoing efforts to refine, generate and characterize new genetically modified rat models needed by the research community will be performed. To expand the broad utility of the RRRC, we will continue to serve as consultants to the community and we will increase our fee-for-services in the areas of model generation, model characterization, colony management, cryopreservation and rederivation. By providing accessible expertise to investigators working with rats and by expanding our available materials and services, the RRRC will continue to serve as a much-needed “one stop” resource for investigators using rats in biomedical research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,254,237 )
2025	2025	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	25	2/26/2025	NON-COMPETING CONTINUATION	$1,254,237
2025	2024	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	24	10/22/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,254,237

Issue Date FY: 2024 ( Subtotal = $1,596,468 )
2024	2024	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	24	6/24/2024	SUPPLEMENT FOR EXPANSION	$296,276
2024	2024	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	24	1/24/2024	NON-COMPETING CONTINUATION	$1,040,153
2024	2024	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	24	5/14/2024	NON-COMPETING CONTINUATION	$260,039
														Subtotal = $1,596,468

Issue Date FY: 2023 ( Subtotal = $1,287,122 )
2023	2023	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	23	1/26/2023	NON-COMPETING CONTINUATION	$1,158,409
2023	2023	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	23	2/22/2023	NON-COMPETING CONTINUATION	$128,713
2023	2021	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	21	8/3/2023	COMPETING CONTINUATION	$203,819
2023	2020	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	20	8/3/2023	NON-COMPETING CONTINUATION	-$203,819
														Subtotal = $1,287,122

Issue Date FY: 2022 ( Subtotal = $1,691,584 )
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	22	7/29/2022	SUPPLEMENT FOR EXPANSION	$241,421
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	22	5/24/2022	NON-COMPETING CONTINUATION	$128,603
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	22	6/29/2022	SUPPLEMENT FOR EXPANSION	$176,157
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	22	2/1/2022	NON-COMPETING CONTINUATION	$1,157,403
2022	2020	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	004	20	9/15/2022	NON-COMPETING CONTINUATION	-$12,000
														Subtotal = $1,691,584

Issue Date FY: 2021 ( Subtotal = $1,432,348 )
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	21	4/6/2021	COMPETING CONTINUATION	-$158,247
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	21	4/1/2021	COMPETING CONTINUATION	$1,450,966
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	21	8/19/2021	SUPPLEMENT FOR EXPANSION	$139,629
2021	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	20	4/1/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,432,348

Issue Date FY: 2020 ( Subtotal = $1,585,822 )
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	004	20	9/3/2020	SUPPLEMENT FOR EXPANSION	$9,735
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	20	8/28/2020	SUPPLEMENT FOR EXPANSION	$194,215
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	20	3/10/2020	NON-COMPETING CONTINUATION	$1,381,872
2020	2019	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	19	12/27/2019	NON-COMPETING CONTINUATION	$0
2020	2019	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	19	1/3/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,585,822

Issue Date FY: 2019 ( Subtotal = $1,381,872 )
2019	2019	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	19	3/2/2019	NON-COMPETING CONTINUATION	$1,381,872
														Subtotal = $1,381,872

Issue Date FY: 2018 ( Subtotal = $1,757,284 )
2018	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	18	8/20/2018	SUPPLEMENT FOR EXPANSION	$375,412
2018	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	18	2/22/2018	NON-COMPETING CONTINUATION	$1,243,685
2018	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	18	6/18/2018	NON-COMPETING CONTINUATION	$138,187
														Subtotal = $1,757,284

Issue Date FY: 2017 ( Subtotal = $1,735,754 )
2017	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	009	17	8/21/2017	SUPPLEMENT FOR EXPANSION	$92,020
2017	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	008	17	8/4/2017	NON-COMPETING CONTINUATION	$69,093
2017	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	17	1/19/2017	NON-COMPETING CONTINUATION	$1,243,685
2017	2016	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	16	12/12/2016	COMPETING CONTINUATION	-$1,492,250
2017	2016	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	005	16	6/15/2017	COMPETING CONTINUATION	$165,478
2017	2016	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	006	16	6/15/2017	COMPETING CONTINUATION	$165,478
2017	2016	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	007	16	6/15/2017	COMPETING CONTINUATION	$165,478
2017	2015	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	004	15	6/15/2017	NON-COMPETING CONTINUATION	-$165,478
2017	2015	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	15	6/14/2017	NON-COMPETING CONTINUATION	$1,354,778
2017	2014	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	14	6/14/2017	SUPPLEMENT FOR EXPANSION	$137,472
														Subtotal = $1,735,754

Issue Date FY: 2016 ( Subtotal = $1,381,871 )
2016	2016	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	000	16	3/3/2016	COMPETING CONTINUATION	$1,381,871
														Subtotal = $1,381,871

Issue Date FY: 2015 ( Subtotal = $1,354,778 ) (Continued on the next page)
2015	2015	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	002	15	6/9/2015	NON-COMPETING CONTINUATION	$1,354,778
Grand Total All Awards = $20,743,030

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Rat Resource and Research Center

Award Number: P40OD011062

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/01/2001

PERIOD OF PERFORMANCE END DATE: 01/31/2026

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