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National Xenopus Resource Center

Award Number: P40OD010997
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

View Award Abstract

Project Summary – Overall Component This project supports continued funding for the National Xenopus Resource (NXR) located at the Marine Biological Laboratory in Woods Hole, MA. The NXR is one of the top priorities for the Xenopus community. The NXR was established in 2010 to serve as a national resource for researchers working with the Xenopus amphibian model system, which includes two species Xenopus laevis and Xenopus tropicalis. The NXR serves as a national repository for community-generated animal stocks as well as serving as an advanced training venue that greatly facilitates productivity for a multitude of researchers. It is a community-oriented resource center that serves all Xenopus researchers, including individuals from large research-focused universities to small liberal arts colleges. As biological research becomes ever more complex, often requiring specialized animal lines and involving diverse technologies, individual laboratory units become insufficient to meet all of the demands required for addressing significant biological problems and a centralized repository or stock center becomes essential. There are four aims to this grant. First, the NXR will maintain current stocks of frogs as well as obtain new lines making them available to the community; this includes special inbred, wild type and mutant lines of both species. In the second aim we outline the NXR research services that meet community demand, including creation of transgenic and mutant animals. In the third aim we outline the resources that we have developed to enable novel Xenopus research, including advanced training workshops (bioinformatics, advanced imaging, genome editing) taught by experts in each field that serve to teach and propagate specialized techniques. The last aim is the applied research aim. In Aim 4 we outline our goals to define the integration sites for our transgenic animals.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	THE MARINE BIOLOGICAL LABORATORY	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	14	1/30/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $815,538 )
2023	2023	THE MARINE BIOLOGICAL LABORATORY	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	14	4/19/2023	NON-COMPETING CONTINUATION	$660,881
2023	2023	THE MARINE BIOLOGICAL LABORATORY	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	002	14	7/21/2023	SUPPLEMENT FOR EXPANSION	$154,657
2023	2022	THE MARINE BIOLOGICAL LABORATORY	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	13	12/1/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $815,538

Issue Date FY: 2022 ( Subtotal = $965,213 )
2022	2022	THE MARINE BIOLOGICAL LABORATORY	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	13	8/15/2022	SUPPLEMENT FOR EXPANSION	$285,652
2022	2022	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	13	5/12/2022	NON-COMPETING CONTINUATION	$679,561
2022	2022	THE MARINE BIOLOGICAL LABORATORY	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	002	13	8/26/2022	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $965,213

Issue Date FY: 2021 ( Subtotal = $898,922 )
2021	2021	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	004	12	7/31/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2021	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	003	12	7/27/2021	SUPPLEMENT FOR EXPANSION	$201,219
2021	2021	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	002	12	4/16/2021	NON-COMPETING CONTINUATION	$697,703
2021	2020	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	11	4/12/2021	COMPETING CONTINUATION	$6,222
2021	2019	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	10	4/12/2021	NON-COMPETING CONTINUATION	-$6,222
														Subtotal = $898,922

Issue Date FY: 2020 ( Subtotal = $704,720 )
2020	2020	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	003	11	5/1/2020	COMPETING CONTINUATION	$704,720
2020	2014	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	5	10/1/2019	SUPPLEMENT FOR EXPANSION	$0
2020	2014	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	002	5	10/1/2019	SUPPLEMENT FOR EXPANSION	$0
2020	2014	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	5	10/1/2019	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $704,720

Issue Date FY: 2019 ( Subtotal = $671,162 )
2019	2019	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	003	10	4/30/2019	NON-COMPETING CONTINUATION	$671,162
2019	2018	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	002	9	1/25/2019	NON-COMPETING CONTINUATION	$0
2019	2014	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	5	1/9/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2014	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	5	1/9/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $671,162

Issue Date FY: 2018 ( Subtotal = $733,083 )
2018	2018	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	002	9	5/24/2018	NON-COMPETING CONTINUATION	$733,083
2018	2014	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	5	1/24/2018	SUPPLEMENT FOR EXPANSION	$0
2018	2014	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	5	1/24/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $733,083

Issue Date FY: 2017 ( Subtotal = $697,760 )
2017	2017	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	8	5/10/2017	SUPPLEMENT FOR EXPANSION	$417,332
2017	2017	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	003	8	7/18/2017	SUPPLEMENT FOR EXPANSION	$61,921
2017	2017	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	8	4/24/2017	NON-COMPETING CONTINUATION	$592,901
2017	2017	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	002	8	6/28/2017	SUPPLEMENT FOR EXPANSION	-$417,332
2017	2017	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	004	8	7/24/2017	NON-COMPETING CONTINUATION	$42,938
														Subtotal = $697,760

Issue Date FY: 2016 ( Subtotal = $703,778 )
2016	2016	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	7	5/4/2016	NON-COMPETING CONTINUATION	$658,778
2016	2016	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	7	7/13/2016	SUPPLEMENT FOR EXPANSION	$45,000
														Subtotal = $703,778

Issue Date FY: 2015 ( Subtotal = $819,278 )
2015	2015	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	6	5/18/2015	COMPETING CONTINUATION	$658,778
2015	2015	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	6	7/29/2015	SUPPLEMENT FOR EXPANSION	$160,500
														Subtotal = $819,278

Issue Date FY: 2014 ( Subtotal = $895,861 )
2014	2014	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	5	8/15/2014	SUPPLEMENT FOR EXPANSION	$250,000
2014	2014	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	5	4/9/2014	NON-COMPETING CONTINUATION	$645,861
														Subtotal = $895,861

Issue Date FY: 2013 ( Subtotal = $632,969 )
2013	2013	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	001	4	8/16/2013	NON-COMPETING CONTINUATION	$0
2013	2013	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	4	5/16/2013	NON-COMPETING CONTINUATION	$632,969
														Subtotal = $632,969

Issue Date FY: 2012 ( Subtotal = $666,146 )
2012	2012	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Research Infrastructure Programs	000	3	5/4/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$666,146
														Subtotal = $666,146

Grand Total All Awards = $9,204,430

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National Xenopus Resource Center

Award Number: P40OD010997

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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