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University of Arizona Cancer Center - Cancer Center Support Grant [MICEO Administrative Supplement]

Award Number: P30CA023074
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/01/1997
PERIOD OF PERFORMANCE END DATE: 07/31/2027

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University of Arizona Cancer Center - Cancer Center Support Grant [MICEO Administrative Supplement] - ABSTRACT An estimated 62% (37 million) of Mexican-origin (MO) adults in the U.S. are predisposed to non-alcoholic fatty liver disease (NAFLD), an emerging risk factor for hepatocellular carcinoma (HCC). This is of particular concern in the Southern Arizona U.S.-Mexico border region as liver disease and liver cancer, are among the leading causes of death for MO adults. Significant disparities in the incidence and mortality of HCC in the U.S. exist across racial/ethnic and gender groups. Specifically, HCC incidence rates are two-fold higher in Hispanic populations overall compared to non-Hispanic whites. Further, HCC is one of the most fatal cancers; the 5-year cause-specific survival for Hispanics is 19%, rendering it the 3rd leading cause of cancer death in Hispanic men and the 5th leading cause in Hispanic women. Despite MO experiencing higher rates and worse outcomes for NAFLD and HCC compared to all racial and ethnic groups and other Hispanic populations, our preliminary work suggest awareness of NAFLD is low in Southern Arizona. Therefore, there is a critical need to improve liver disease and cancer health literacy for MO adults to reduce the disparities among this high-risk population. In the absence of such tools, the prevalence, morbidity, and economic costs associated with NAFLD and HCC in this population are likely to continue rising. The proposed research will address this gap by implementing a culturally tailored, multi-channel educational communication campaign to increase knowledge and public awareness of liver disease and liver cancer risk factors in MO. To achieve this objective, we will leverage our current screening and education efforts for liver disease prevention and treatment in Southern Arizona, the University of Arizona Cancer Center (UACC) catchment area. Further, we will leverage a NAFLD awareness multi-media educational communication campaign developed in partnership with El Rio Community Health Center, a Federally Qualified Health Center, including community-based education supported by promotoras de salud (community health workers). We will (1) evaluate the effectiveness of a culturally tailored, multi-channel educational communication campaign to improve knowledge and public awareness of liver disease and liver cancer risk factors in MO communities in Southern Arizona; and (2) determine the impact of promotora-led outreach, engagement, and education for cancer prevention and treatment in community-based settings. The proposed project will provide much needed evidence to inform the Community Preventive Services Task Force recommendations for engaging promotoras to increase knowledge and public awareness of liver disease and liver cancer risk factors in MO, particularly for this high-risk, underserved population.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $3,936,608 )
2024	2024	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	002	43	7/31/2024	NON-COMPETING CONTINUATION	$3,736,608
2024	2024	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	003	43	8/27/2024	SUPPLEMENT FOR EXPANSION	$200,000
2024	2023	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	001	42	10/30/2023	SUPPLEMENT FOR EXPANSION	$0
2024	2023	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	000	42	10/30/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,936,608

Issue Date FY: 2023 ( Subtotal = $3,936,608 )
2023	2023	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	005	42	9/13/2023	SUPPLEMENT FOR EXPANSION	$200,000
2023	2023	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	006	42	9/14/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2023	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	004	42	7/28/2023	NON-COMPETING CONTINUATION	$3,736,608
2023	2022	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	003	41	4/6/2023	COMPETING CONTINUATION	$1,331,666
2023	2021	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	40	4/6/2023	SUPPLEMENT FOR EXPANSION	-$294,650
2023	2021	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	001	40	4/6/2023	SUPPLEMENT FOR EXPANSION	-$17,679
2023	2021	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Cancer Centers Support Grants	000	40	4/6/2023	SUPPLEMENT FOR EXPANSION	-$1,019,337
														Subtotal = $3,936,608

Issue Date FY: 2022 ( Subtotal = $4,736,608 )
2022	2022	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	001	41	8/5/2022	COMPETING CONTINUATION	$138,804
2022	2022	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	41	8/24/2022	SUPPLEMENT FOR EXPANSION	$1,000,000
2022	2022	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	000	41	8/4/2022	COMPETING CONTINUATION	$3,597,804
														Subtotal = $4,736,608

Issue Date FY: 2021 ( Subtotal = $4,519,488 )
2021	2021	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	004	40	8/6/2021	SUPPLEMENT FOR EXPANSION	$1,000,000
2021	2021	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	002	40	7/1/2021	SUPPLEMENT FOR EXPANSION	$3,459,488
2021	2021	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	003	40	7/19/2021	SUPPLEMENT FOR EXPANSION	$60,000
2021	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	000	40	11/3/2020	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	40	11/19/2020	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $4,519,488

Issue Date FY: 2020 ( Subtotal = $4,960,491 )
2020	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	004	40	9/17/2020	SUPPLEMENT FOR EXPANSION	$150,000
2020	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	001	40	7/31/2020	SUPPLEMENT FOR EXPANSION	$60,000
2020	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	002	40	8/5/2020	SUPPLEMENT FOR EXPANSION	$1,000,000
2020	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	005	40	9/18/2020	SUPPLEMENT FOR EXPANSION	$191,000
2020	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	003	40	9/11/2020	SUPPLEMENT FOR EXPANSION	$100,000
2020	2020	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	000	40	7/1/2020	NON-COMPETING CONTINUATION	$3,459,491
														Subtotal = $4,960,491

Issue Date FY: 2019 ( Subtotal = $4,332,279 )
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	39	8/7/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	007	39	9/12/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	000	39	7/1/2019	NON-COMPETING CONTINUATION	$3,467,380
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Trans-NIH Research Support	009	39	9/12/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	005	39	8/29/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	008	39	9/12/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Trans-NIH Research Support	004	39	8/26/2019	SUPPLEMENT FOR EXPANSION	$214,900
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	003	39	8/21/2019	SUPPLEMENT FOR EXPANSION	$400,000
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	39	7/10/2019	SUPPLEMENT FOR EXPANSION	$249,999
2019	2019	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	006	39	9/12/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,332,279

Issue Date FY: 2018 ( Subtotal = $4,395,422 )
2018	2018	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	000	38	6/29/2018	NON-COMPETING CONTINUATION	$3,533,423
2018	2018	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	004	38	9/6/2018	SUPPLEMENT FOR EXPANSION	$300,000
2018	2018	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	38	8/22/2018	SUPPLEMENT FOR EXPANSION	$249,999
2018	2018	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	003	38	8/23/2018	SUPPLEMENT FOR EXPANSION	$112,000
2018	2018	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	001	38	8/21/2018	SUPPLEMENT FOR EXPANSION	$200,000
														Subtotal = $4,395,422

Issue Date FY: 2017 ( Subtotal = $3,608,423 ) (Continued on the next page)
2017	2017	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	003	37	6/26/2017	NON-COMPETING CONTINUATION	$3,533,423
2017	2017	UNIVERSITY OF ARIZONA	888 N EUCLID AVE RM 510	TUCSON	AZ	85719	PIMA	USA	Cancer Centers Support Grants	004	37	6/27/2017	SUPPLEMENT FOR EXPANSION	$75,000
Grand Total All Awards = $103,474,820

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University of Arizona Cancer Center - Cancer Center Support Grant [MICEO Administrative Supplement]

Award Number: P30CA023074

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/01/1997

PERIOD OF PERFORMANCE END DATE: 07/31/2027

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