Tuesday, July 1, 2025 7/1/2025

Claude D. Pepper Older Americans Independence Center (P30 Clinical Trial Optional)

Award Number: P30AG067988
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2021
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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Claude D. Pepper Older Americans Independence Center (P30 Clinical Trial Optional) - PROJECT SUMMARY OVERALL This proposal seeks to establish the Claude D Pepper Older Americans Independence Center at UConn (UConn OAIC) with the overarching goal of developing clinical strategies for enhancing function and independence in older adults that are more precise, personalized, and effective. Our focus on Precision Gerontology has emerged through the collective experiences and insights of our multidisciplinary team of accomplished investigators in the UConn Center on Aging – all united by a shared commitment to improving the lives of older adults through research, education, and clinical care. Our emphasis on Precision Gerontology has been guided by three principles: 1. A growing heterogeneity or variability over time among individuals involving all aspects of aging that therefore necessitates a multidisciplinary team-based approach to aging research; 2. Increased heterogeneity or variability with aging in older adults’ responses to treatment, highlighting the need for better targeting; and 3. Recognition of a need to incorporate these considerations into the design and testing of novel geroscience-guided therapies. These objectives will be achieved by establishing a UConn OAIC through the coordinated activities of a Leadership and Administration Core (LAC), Recruitment and Community Engagement Core (RC1), Data Resource Core (RC2), Biomarker and Preclinical Research Core (RC3), Pilot and Exploratory Studies Core (PESC), and Research Education Component (REC). We will seek to address these goals through the following aims: Aim 1: To develop and refine new approaches to the study and clinical translation of Precision Gerontology. Aim 2: To develop and evaluate new research methods, techniques, and collaborative approaches required to advance the goals of Precision Gerontology. Aim 3: To identify, develop, and learn from experiences of the next generation of researchers poised to become leaders in geriatrics research related to the UConn OAIC focus. Aim 4: To select and support innovative pilot studies that show promise in helping to guide the design, funding, and completion of more definitive future research studies related to the UConn OAIC focus.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,333,352 )
2025	2025	UNIVERSITY OF CONNECTICUT HEALTH CENTER	263 FARMINGTON AVE	FARMINGTON	CT	06030	CAPITOL	USA	Aging Research	000	5	6/20/2025	NON-COMPETING CONTINUATION	$1,333,352
														Subtotal = $1,333,352

Issue Date FY: 2024 ( Subtotal = $1,345,076 )
2024	2024	UNIVERSITY OF CONNECTICUT HEALTH CENTER	263 FARMINGTON AVE	FARMINGTON	CT	06030	CAPITOL	USA	Aging Research	001	4	7/22/2024	NON-COMPETING CONTINUATION	$1,345,076
2024	2023	UNIVERSITY OF CONNECTICUT HEALTH CENTER	263 FARMINGTON AVE	FARMINGTON	CT	06030	CAPITOL	USA	Aging Research	000	3	3/12/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,345,076

Issue Date FY: 2023 ( Subtotal = $1,350,157 )
2023	2023	UNIVERSITY OF CONNECTICUT HEALTH CENTER	263 FARMINGTON AVE	FARMINGTON	CT	06030	CAPITOL	USA	Aging Research	001	3	8/7/2023	NON-COMPETING CONTINUATION	$1,350,157
2023	2022	UNIVERSITY OF CONNECTICUT	263 FARMINGTON AVE, ASB #3	FARMINGTON	CT	06032	CAPITOL	USA	Aging Research	000	2	1/20/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,350,157

Issue Date FY: 2022 ( Subtotal = $1,352,835 )
2022	2022	UNIVERSITY OF CONNECTICUT	263 FARMINGTON AVE, ASB #3	FARMINGTON	CT	06032	CAPITOL	USA	Aging Research	001	2	7/19/2022	NON-COMPETING CONTINUATION	$1,352,835
2022	2021	UNIVERSITY OF CONNECTICUT	263 FARMINGTON AVE, ASB #3	FARMINGTON	CT	06032	CAPITOL	USA	Aging Research	000	1	1/27/2022	NEW	$0
														Subtotal = $1,352,835

Issue Date FY: 2021 ( Subtotal = $1,484,144 )
2021	2021	UNIVERSITY OF CONNECTICUT	263 FARMINGTON AVE, ASB #3	FARMINGTON	CT	06032	CAPITOL	USA	Aging Research	000	1	8/9/2021	NEW	$1,484,144
														Subtotal = $1,484,144

Grand Total All Awards = $6,865,564

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Claude D. Pepper Older Americans Independence Center (P30 Clinical Trial Optional)

Award Number: P30AG067988

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2021

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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