Tuesday, July 1, 2025 7/1/2025

Northwell Roybal Center for Personalized Trials: Physical Activity Promotion for Persons Giving Care or Living with AD/ADRD

Award Number: P30AG063786
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2020
PERIOD OF PERFORMANCE END DATE: 05/31/2029

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Northwell Roybal Center for Personalized Trials: Physical Activity Promotion for Persons Giving Care or Living with AD/ADRD - PROJECT ABSTRACT The goal of this Northwell Roybal Center for Personalized Trials: Physical Activity Promotion for Persons Giving Care or Living with AD/ADRD is to generate behavioral intervention development research for enhancing physical activity (Roybal Theme: Spur the Initiation and Maintenance of Physical Activity Regimens that are Personalized to Caregivers or Persons with AD/ADRD). The Northwell Roybal Center is comprised of two components: the Administrative Core and the Behavioral Intervention Development Core. Our Administrative Core will develop and provide the strategic vision, leadership, and the full range of NIH Stage Model expertise needed for the success of this Roybal Center; monitor Center clinical trials progress and provide immediate feedback; develop, identify, and use common metrics for Center productivity evaluation purposes. Finally, the core will facilitate collaboration with other Roybal Centers, the Coordinating Center, the National Institute on Aging, and scientists across the nation interested in advancing the initiation and maintenance of physical activity regimens personalized to care providers or those living with AD/ADRD. Our Behavioral Intervention Development (BID) Core will proactively determine a national pool of potential eligible scientists for later national competitions, review and select meritorious clinical trials for funding, and ensure compliance of all clinical trials with all regulatory agencies. The BID will then support investigators identified via this national competition to implement identified innovative clinical trials that align with the themes of the Northwell Roybal Center in Years 3 through 5 of the proposed project. The BID Core will also support the conduct of two Stage II fully-powered clinical trials in Years 1 and 2 that aim to foster habitual physical among caregivers for persons with AD/ADRD. Trial #1 will work to develop habitual daily walking among caregivers. In contrast, Trial #2 will develop habitual hourly walking to reduce the amount of time caregivers spend sedentary. Both trials will measure the key mechanism of behavior (MoBC) of cognitive automaticity. The overall mission of the Northwell Roybal Center for Personalized Trials is to establish an infrastructure organized per the NIH Stage Model with scientiﬁc expertise and resources to conduct Stages 0-V trials of the translational behavioral intervention development pipeline, as well as examining key MoBCs of behavior change, and so serve as a national resource for the behavioral and social intervention research community in initiating and maintaining personalized physical activity regimen for caregivers or persons living with AD/ADRD.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	002	5	6/12/2025	COMPETING CONTINUATION	$139,879
2025	2024	THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	000	5	12/18/2024	COMPETING CONTINUATION	$0
2025	2023	THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	001	4	6/12/2025	NON-COMPETING CONTINUATION	-$139,879
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $1,271,724 )
2024	2024	THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	001	5	8/1/2024	COMPETING CONTINUATION	$0
2024	2024	THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	000	5	7/19/2024	COMPETING CONTINUATION	$1,271,724
2024	2024	THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	002	5	9/6/2024	COMPETING CONTINUATION	$0
														Subtotal = $1,271,724

Issue Date FY: 2023 ( Subtotal = $428,158 )
2023	2023	FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH, THE	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	001	4	5/15/2023	NON-COMPETING CONTINUATION	$428,158
2023	2022	FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH, THE	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	000	3	2/7/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $428,158

Issue Date FY: 2022 ( Subtotal = $429,384 )
2022	2022	FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH, THE	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	001	3	7/19/2022	NON-COMPETING CONTINUATION	$429,384
2022	2021	FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH, THE	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	000	2	1/13/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $429,384

Issue Date FY: 2021 ( Subtotal = $433,943 )
2021	2021	FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH, THE	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	001	2	8/6/2021	NON-COMPETING CONTINUATION	$433,943
2021	2020	FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH, THE	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	000	1	2/1/2021	NEW	$0
														Subtotal = $433,943

Issue Date FY: 2020 ( Subtotal = $472,219 )
2020	2020	FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE	350 COMMUNITY DR	MANHASSET	NY	11030	NASSAU	USA	Aging Research	000	1	8/12/2020	NEW	$472,219
														Subtotal = $472,219

Grand Total All Awards = $3,035,428

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Northwell Roybal Center for Personalized Trials: Physical Activity Promotion for Persons Giving Care or Living with AD/ADRD

Award Number: P30AG063786

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2020

PERIOD OF PERFORMANCE END DATE: 05/31/2029

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