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San Antonio Claude D. Pepper Older Americans Independence Center

Award Number: P30AG044271
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/15/2015
PERIOD OF PERFORMANCE END DATE: 07/31/2030

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San Antonio Claude D. Pepper Older Americans Independence Center - Established in 2015, the San Antonio Claude D. Pepper Older Americans Independence Center (SA OAIC) is the first focused on the concept of geroscience. It has spearheaded high impact research in humans and nonhuman primates on virtually all hallmarks of aging, including groundbreaking first-in-human trials of senolytics, repurposing drugs to target age-related diseases and frailty, lifestyle interventions to improve health outcomes in older adults, and identification of new targets for interventions. Based on its theme, “Translational geroscience to improve the health and functional independence of all older adults”, the SA OAIC will pursue four programmatic Specific Aims: 1. Move basic geroscience discoveries into interventions to improve the health and functional independence in all populations of older adults. 2. Develop the future leaders in translational geroscience and geriatrics. 3. Partner with other OAICs, NIA/NIH Centers, and institutions on geroscience and clinical trial initiatives. 4. Broadly disseminate discoveries and innovations in translational geroscience. The SA OAIC renewal builds on the considerable scientific accomplishments achieved in the current cycle (2020-2024) by supporting 13 early career investigators, 19 pilot studies and developmental projects, and 41 externally funded projects, and the new opportunities provided by the recruitment of new talent to the OAIC program. The SA OAIC will increase its focus on function, with new emphasis on health outcomes variability in the populations of South Texas, which experience an earlier onset of age-related morbidities and functional decline. Thus, geroscience strategies may have a greater impact in this population. SA OAIC will also leverage the new fullservice drug development and testing pipeline created in collaboration with other institutional programs to identify new targets and develop new age-modulating drugs for rapid testing in unique preclinical primate models and first-in-human trials. The SA OAIC will advance its aims by supporting four Scholars, five pilot studies, eight developmental and 16 externally funded projects and enhanced core infrastructure which includes four highly productive Resource Cores: Preclinical Research, Clinical Research, Molecular Phenotyping, and Biostatistics and Informatics. Under the dedicated leadership of Drs. Elena Volpi, Randy Strong and Rebeca Wong, the Leadership and Administrative Core will coordinate resource core activities with those of the Research Education Component and the Pilot and Exploratory Studies Core.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $1,291,189 )
2026	2026	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	003	12	8/3/2026	NON-COMPETING CONTINUATION	$1,291,189
2026	2025	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	001	11	5/5/2026	COMPETING CONTINUATION	$0
2026	2025	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	002	11	7/24/2026	COMPETING CONTINUATION	$0
2026	2024	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	10	3/17/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,291,189

Issue Date FY: 2025 ( Subtotal = $1,335,243 )
2025	2025	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	001	11	8/29/2025	COMPETING CONTINUATION	$1,335,243
2025	2024	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	10	7/30/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,335,243

Issue Date FY: 2024 ( Subtotal = $1,242,626 )
2024	2024	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	001	10	7/25/2024	NON-COMPETING CONTINUATION	$1,242,626
2024	2023	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	9	4/18/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,242,626

Issue Date FY: 2023 ( Subtotal = $1,242,626 )
2023	2023	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	003	9	8/17/2023	NON-COMPETING CONTINUATION	$0
2023	2023	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	004	9	8/22/2023	NON-COMPETING CONTINUATION	$0
2023	2023	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	002	9	8/3/2023	NON-COMPETING CONTINUATION	$1,242,626
2023	2022	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	8	11/25/2022	NON-COMPETING CONTINUATION	$0
2023	2022	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	001	8	6/16/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,242,626

Issue Date FY: 2022 ( Subtotal = $1,266,861 )
2022	2022	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	002	8	7/22/2022	NON-COMPETING CONTINUATION	$1,266,861
2022	2021	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	7	3/4/2022	NON-COMPETING CONTINUATION	$0
2022	2021	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	001	7	4/7/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,266,861

Issue Date FY: 2021 ( Subtotal = $1,353,062 )
2021	2021	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	002	7	7/22/2021	NON-COMPETING CONTINUATION	$1,353,062
2021	2020	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	001	6	3/9/2021	COMPETING CONTINUATION	$511,142
2021	2019	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	5	3/9/2021	NON-COMPETING CONTINUATION	-$511,142
														Subtotal = $1,353,062

Issue Date FY: 2020 ( Subtotal = $1,242,840 )
2020	2020	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	001	6	7/22/2020	COMPETING CONTINUATION	$1,242,840
2020	2019	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	5	2/4/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,242,840

Issue Date FY: 2019 ( Subtotal = $1,036,987 )
2019	2019	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	001	5	4/26/2019	NON-COMPETING CONTINUATION	$703,702
2019	2018	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	4	2/21/2019	NON-COMPETING CONTINUATION	$333,285
														Subtotal = $1,036,987

Issue Date FY: 2018 ( Subtotal = $703,702 )
2018	2018	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	4	4/25/2018	NON-COMPETING CONTINUATION	$703,702
														Subtotal = $703,702

Issue Date FY: 2017 ( Subtotal = $703,702 )
2017	2017	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	3	7/3/2017	NON-COMPETING CONTINUATION	$703,702
														Subtotal = $703,702

Issue Date FY: 2016 ( Subtotal = $703,702 )
2016	2016	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	2	5/23/2016	NON-COMPETING CONTINUATION	$703,702
														Subtotal = $703,702

Issue Date FY: 2015 ( Subtotal = $703,702 )
2015	2015	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Aging Research	000	1	6/12/2015	NEW	$703,702
														Subtotal = $703,702

Grand Total All Awards = $12,826,242

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San Antonio Claude D. Pepper Older Americans Independence Center

Award Number: P30AG044271

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/15/2015

PERIOD OF PERFORMANCE END DATE: 07/31/2030

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