Thursday, November 21, 2024 11/21/2024

Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related Dementias

Award Number: P01AG005842
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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OTHER PROJECT INFORMATION – Project Summary/Abstract Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related Dementias This Program Project analyzes and seeks to improve healthcare practice patterns, decision-making processes, and treatment effectiveness for patients with Alzheimer’s disease and related dementias (ADRD). Supported by a set of cores that draw together clinical and economic expertise, vast novel data sources, and cutting-edge analytical tools, the component projects focus on the particular decision-making challenges faced by providers, caregivers, and patients in caring for the complex needs of people living with ADRD and the role these play in driving disparities in access and outcomes. There are unique aspects, potential barriers, and disparities in how healthcare systems provide healthcare to people with ADRD, as these patients may be less capable of describing their symptoms and health histories, or following through on medical recommendations, and they may rely substantially on formal and informal caregivers in navigating healthcare services. We seek to understand and improve healthcare decision-making and outcomes for patients with these complex needs. The Program’s component research projects address influences on healthcare decisions, and their impact on outcomes and disparities, across a set of health conditions and settings. We deploy innovative machine learning methods both to characterize patients’ needs and treatment patterns and to build tools that can assist physicians with patient diagnostics, even when patients’ communication of their symptoms and health histories may be limited. We examine the factors that affect both provider and patient decision-making, including pressured decision-making environments such as Emergency Departments, patient-provider race, administrative burdens on patients and caregivers such as complex insurance rules, provider incentives, and providers’ patient caseload and fatigue in influencing healthcare delivery and health outcomes for patients with ADRD. Integrative support for the Program Project is advanced through three cores that provide common infrastructure, data, and expertise needed by the projects, and to ensure that they work synergistically and seamlessly as a cohesive program.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $3,185,633 )
2024	2024	NATIONAL BUREAU OF ECONOMIC RESEARCH INC	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	35	9/20/2024	COMPETING CONTINUATION	$3,185,633
2024	2022	NATIONAL BUREAU OF ECONOMIC RESEARCH INC	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	34	11/2/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,185,633

Issue Date FY: 2022 ( Subtotal = $1,696,685 )
2022	2022	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	34	8/2/2022	NON-COMPETING CONTINUATION	$1,731,685
2022	2021	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	33	1/7/2022	NON-COMPETING CONTINUATION	-$35,000
														Subtotal = $1,696,685

Issue Date FY: 2021 ( Subtotal = $2,056,754 )
2021	2021	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	33	8/17/2021	NON-COMPETING CONTINUATION	$1,737,917
2021	2021	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Trans-NIH Research Support	002	33	8/20/2021	SUPPLEMENT FOR EXPANSION	$318,837
2021	2020	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	32	10/19/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,056,754

Issue Date FY: 2020 ( Subtotal = $2,353,759 )
2020	2020	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	002	32	9/4/2020	SUPPLEMENT FOR EXPANSION	$161,388
2020	2020	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	32	7/31/2020	SUPPLEMENT FOR EXPANSION	$447,421
2020	2020	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	32	7/27/2020	NON-COMPETING CONTINUATION	$1,744,950
														Subtotal = $2,353,759

Issue Date FY: 2019 ( Subtotal = $1,747,167 )
2019	2019	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	31	8/7/2019	NON-COMPETING CONTINUATION	$1,747,167
2019	2019	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	002	31	8/23/2019	NON-COMPETING CONTINUATION	$0
2019	2017	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	30	2/5/2019	COMPETING CONTINUATION	$0
														Subtotal = $1,747,167

Issue Date FY: 2018 ( Subtotal = $0 )
2018	2017	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	30	3/26/2018	COMPETING CONTINUATION	$788,206
2018	2017	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	002	30	8/13/2018	COMPETING CONTINUATION	$0
2018	2015	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	29	3/26/2018	NON-COMPETING CONTINUATION	-$788,206
														Subtotal = $0

Issue Date FY: 2017 ( Subtotal = $1,755,747 )
2017	2017	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	002	30	9/20/2017	COMPETING CONTINUATION	$1,755,747
2017	2015	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	29	9/19/2017	NON-COMPETING CONTINUATION	$0
2017	2015	NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	29	6/30/2017	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,755,747

Issue Date FY: 2015 ( Subtotal = $2,264,526 )
2015	2015	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	29	7/16/2015	NON-COMPETING CONTINUATION	$2,264,526
														Subtotal = $2,264,526

Issue Date FY: 2014 ( Subtotal = $2,220,351 )
2014	2014	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	28	7/16/2014	NON-COMPETING CONTINUATION	$2,220,351
														Subtotal = $2,220,351

Issue Date FY: 2013 ( Subtotal = $2,097,426 )
2013	2013	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	27	8/26/2013	NON-COMPETING CONTINUATION	$2,097,426
														Subtotal = $2,097,426

Issue Date FY: 2012 ( Subtotal = $2,218,420 )
2012	2012	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	26	8/17/2012	NON-COMPETING CONTINUATION	$2,218,420
														Subtotal = $2,218,420

Issue Date FY: 2011 ( Subtotal = $2,210,747 )
2011	2011	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	25	9/21/2011	COMPETING CONTINUATION	$2,210,747
2011	2010	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Trans-NIH Recovery Act Research Support	000	24	9/21/2011	COMPETING CONTINUATION	$0
2011	2010	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Trans-NIH Recovery Act Research Support	002	24	9/23/2011	COMPETING CONTINUATION	$0
														Subtotal = $2,210,747

Issue Date FY: 2010 ( Subtotal = $2,189,997 )
2010	2010	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Trans-NIH Recovery Act Research Support	000	24	4/20/2010	COMPETING CONTINUATION	$2,189,997
														Subtotal = $2,189,997

Issue Date FY: 2008 ( Subtotal = $2,428,060 )
2008	2008	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	23	4/21/2008	NON-COMPETING CONTINUATION	$2,309,622
2008	2008	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	22	1/11/2008	SUPPLEMENT FOR EXPANSION	$118,438
														Subtotal = $2,428,060

Issue Date FY: 2007 ( Subtotal = $2,562,155 )
2007	2007	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	22	4/23/2007	NON-COMPETING CONTINUATION	$2,562,155
														Subtotal = $2,562,155

Issue Date FY: 2006 ( Subtotal = $2,662,820 )
2006	2006	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	000	21	4/28/2006	NON-COMPETING CONTINUATION	$2,513,990
2006	2006	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	21	5/10/2006	SUPPLEMENT FOR EXPANSION	$148,830
														Subtotal = $2,662,820

Issue Date FY: 2005 ( Subtotal = $2,497,519 ) (Continued on the next page)
2005	2005	NATIONAL BUREAU OF ECONOMIC RESEARCH	1050 MASSACHUSETTS AVE	CAMBRIDGE	MA	02138	MIDDLESEX	USA	Aging Research	001	20	8/26/2005	SUPPLEMENT FOR EXPANSION	$99,284
Grand Total All Awards = $50,093,529

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Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related Dementias

Award Number: P01AG005842

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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