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All of Us Research Program Heartland Consortium (AoURP-HC)

Award Number: OT2OD036430
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: OTHER
PERIOD OF PERFORMANCE START DATE: 09/01/2023
PERIOD OF PERFORMANCE END DATE: 08/31/2026

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All of Us Research Program Heartland Consortium (AoURP-HC) - Residents of rural communities and the Midwest region of the United States experience disproportionately high rates of chronic disease, defined by the US Center for Disease Control and Prevention as conditions that persist for a year or more, require ongoing medical care, and often limit daily functioning. Rural populations face numerous challenges that negatively impact health outcomes and contribute to chronic disease, including limited access to healthcare, environmental and occupational hazards, and population characteristics such as lower socioeconomic status, lower education levels, and an aging demographic. Chronic diseases are the leading cause of illness, disability, and death in the U.S., with five of the top ten causes of death linked to preventable and treatable chronic conditions. Chronic disease is also a leading driver in annual health care costs. The cost of chronic disease is estimated to be over one trillion dollars annually to the American medical system. This proposal aims to expand participation of rural and Midwestern populations, including pediatric populations, in the largest precision medicine initiative in history by incorporating the All of Us Research Program Heartland Consortium (AoURP-HC) as a Healthcare Provider Organization (HPO) into the National Institutes of Health's (NIH) All of Us Research Program (AoURP). The AoURP-HC is a partnership of academic medical centers, hospitals, and community organizations in the central United States that will work together to enroll Kansas, Missouri, Nebraska, and Iowa residents into the AoURP. By increasing representation of rural and Midwestern populations through program enrollment, the AoURP-HC will help advance the long-term goals of the AoURP: delivering more personalized, effective care and developing innovative strategies for improving health outcomes and disease prevention that benefit all individuals—regardless of geography or background.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,500,000 )
2025	2025	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	Trans-NIH Research Support	002	1	8/13/2025	SUPPLEMENT FOR EXPANSION	$1,500,000
2025	2024	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	21st Century Cures Act - Precision Medicine Initiative	001	1	11/13/2024	SUPPLEMENT FOR EXPANSION	$0
2025	2023	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	21st Century Cures Act - Precision Medicine Initiative	003	1	8/14/2025	NEW	$0
2025	2023	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	11/13/2024	NEW	$0
														Subtotal = $1,500,000

Issue Date FY: 2024 ( Subtotal = $2,800,000 )
2024	2024	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	21st Century Cures Act - Precision Medicine Initiative	001	1	8/23/2024	SUPPLEMENT FOR EXPANSION	$2,800,000
2024	2023	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	8/23/2024	NEW	$0
														Subtotal = $2,800,000

Issue Date FY: 2023 ( Subtotal = $6,349,986 )
2023	2023	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	8/31/2023	NEW	$6,349,986
														Subtotal = $6,349,986

Grand Total All Awards = $10,649,986

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All of Us Research Program Heartland Consortium (AoURP-HC)

Award Number: OT2OD036430

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: OTHER

PERIOD OF PERFORMANCE START DATE: 09/01/2023

PERIOD OF PERFORMANCE END DATE: 08/31/2026

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