Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Bridge2AI:Salutogenesis Data Generation Project

Award Number: OT2OD032644
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: OTHER
PERIOD OF PERFORMANCE START DATE: 09/01/2025
PERIOD OF PERFORMANCE END DATE: 11/30/2026

Group Awards By:

View Award Description

Bridge2AI:Salutogenesis Data Generation Project - Abstract Text The Artificial Intelligence Ready and Exploratory Atlas for Diabetes Insights (AI-READI) project is one of the data generation projects in the NIH Common Fund’s Bridge2AI program. The project seeks to create a flagship ethically-sourced dataset to enable future generations of artificial intelligence/machine learning (AI/ML) research to provide critical insights into type 2 diabetes mellitus (T2DM), including salutogenic pathways to return to health. The ability to understand and affect the course of complex, multi-organ diseases such as T2DM has been limited by a lack of well-designed, high quality, and large multimodal datasets. The team of investigators will aim to collect a cross-sectional dataset of 4,000+ people and longitudinal data from 10% of the study cohort across the US. The study cohort will be balanced for diabetes disease stage. Data collection will be specifically designed to permit downstream pseudotime manifold analysis, an approach used to predict disease trajectories by collecting and learning from complex, multimodal data from participants with differing disease severity (normal to insulin-dependent T2DM). The long-term objective for this project is to develop a foundational dataset in diabetes, agnostic to existing classification criteria, which can be used to reconstruct a temporal atlas of T2DM development and reversal towards health (i.e., salutogenesis). Six cross-disciplinary project modules involving teams located across eight institutions will work together to develop this flagship dataset. All data will be optimized for downstream AI/ML research and made publicly available. . The AI-READI project will also engage in a tribal consultation to address barriers and facilitators of participation with the goal of collecting similar data within a Native American cohort in an ethical and respectful manner. Specific aims include 1) Collect and share the dataset for AI/ML research according to the Findable, Accessible, Interoperable, Reusable (FAIR) data principles, 2) Create a model for developing large scalable datasets, and 3) Increase access to and quality of AI/ML research by recruiting and training personnel.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $16,005,349 )
2025	2025	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	001	1	11/25/2024	SUPPLEMENT FOR EXPANSION	$7,982,489
2025	2025	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Trans-NIH Research Support	007	2	9/10/2025	SUPPLEMENT FOR EXPANSION	$7,981,760
2025	2025	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	003	1	5/1/2025	SUPPLEMENT FOR EXPANSION	$41,100
2025	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	004	1	8/19/2025	NEW	-$2,811,545
2025	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	002	1	5/1/2025	NEW	$0
2025	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	000	1	11/25/2024	NEW	$0
2025	2022	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Trans-NIH Research Support	006	2	9/10/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2025	2022	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Trans-NIH Research Support	005	2	8/29/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$2,811,545
														Subtotal = $16,005,349

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	001	1	4/5/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	000	1	4/5/2024	NEW	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $8,838,695 )
2023	2023	THE UNIVERSITY OF WASHINGTON VICE PR	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	005	1	9/20/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2023	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	002	1	6/23/2023	SUPPLEMENT FOR EXPANSION	$841,805
2023	2023	THE UNIVERSITY OF WASHINGTON VICE PR	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	004	1	8/31/2023	SUPPLEMENT FOR EXPANSION	$7,996,890
2023	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	001	1	2/14/2023	NEW	$0
2023	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	000	1	12/2/2022	NEW	$0
2023	2022	THE UNIVERSITY OF WASHINGTON VICE PR	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	003	1	8/31/2023	NEW	$0
														Subtotal = $8,838,695

Issue Date FY: 2022 ( Subtotal = $7,838,044 )
2022	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Trans-NIH Research Support	000	1	9/1/2022	NEW	$7,838,044
														Subtotal = $7,838,044

Grand Total All Awards = $32,682,088

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Bridge2AI:Salutogenesis Data Generation Project

Award Number: OT2OD032644

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: OTHER

PERIOD OF PERFORMANCE START DATE: 09/01/2025

PERIOD OF PERFORMANCE END DATE: 11/30/2026

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer