Thursday, July 3, 2025 7/3/2025

PTSC 2.0

Award Number: OT2OD030043
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: OTHER
PERIOD OF PERFORMANCE START DATE: 08/14/2020
PERIOD OF PERFORMANCE END DATE: 02/28/2025

Group Awards By:

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PTSC 2.0 - Building on the current state of success of the AoURP, we recognize a need to enable maximum innovation and flexibility to enroll and retain one million or more diverse participants. Through data-driven strategies, technology solutions, open ecosystem and excellent service, PTSC can help increase efficiency of recruitment, return information and value to participants, increase retention and meet people where they are. Our PTSC 2.0 proposal combines the best of technology, people, and coordination to help the Program succeed. PTSC has been an integral part of innumerable planning sessions with AoURP Leadership working together with the Program Officer, Chief Technology and Chief Experience Officers, communications leads, HPO leads, and genomics lead to create the roadmap necessary for the Program to achieve its mission in the next several years. These interactions shaped the PTSC’s three key overarching themes: • Continuous improvement of existing technology systems and processes based on learnings • Expansion to meet growing needs of AoURP • Innovation to maximize new research strategies and technology solutions To accomplish these aims, the PTSC will operationalize the following five key values: • Openness: Promote, maintain and invite others to openly contribute data and technology to the AoURP • Service: Explicitly serve the program, its participants, and enrollment partners • Acceleration: We must move with haste to address the accelerating scientific needs of the program • Flexibility: Work to ensure that PTSC resources can be allocated responsibly where needed • Security: Continue to vigilantly maintain the rigorous privacy and security standards of the AoURP


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,499,573 )
2025	2025	VIGNET INC.	4114 LEGATO RD FL 9	FAIRFAX	VA	22033	FAIRFAX	USA	21st Century Cures Act - Precision Medicine Initiative	001	1	12/20/2024	SUPPLEMENT FOR EXPANSION	$1,499,573
2025	2023	VIGNET INC.	4114 LEGATO RD FL 9	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	000	1	11/25/2024	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,499,573

Issue Date FY: 2024 ( Subtotal = $17,094,493 )
2024	2024	VIGNET INC.	4114 LEGATO RD FL 9	FAIRFAX	VA	22033	FAIRFAX	USA	21st Century Cures Act - Precision Medicine Initiative	003	1	8/21/2024	SUPPLEMENT FOR EXPANSION	$94,500
2024	2024	VIGNET INC.	4114 LEGATO RD FL 9	FAIRFAX	VA	22033	FAIRFAX	USA	21st Century Cures Act - Precision Medicine Initiative	002	1	5/31/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2024	VIGNET INC.	4114 LEGATO RD FL 9	FAIRFAX	VA	22033	FAIRFAX	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	5/2/2024	SUPPLEMENT FOR EXPANSION	$16,999,993
2024	2023	VIGNET INC.	4114 LEGATO RD FL 9	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	001	1	5/3/2024	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $17,094,493

Issue Date FY: 2023 ( Subtotal = $43,872,265 )
2023	2023	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	003	1	8/5/2023	SUPPLEMENT FOR EXPANSION	$26,078,422
2023	2023	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	002	1	6/16/2023	SUPPLEMENT FOR EXPANSION	$5,268,448
2023	2023	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	001	1	3/24/2023	SUPPLEMENT FOR EXPANSION	$10,045,596
2023	2023	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	000	1	12/19/2022	SUPPLEMENT FOR EXPANSION	$2,479,799
														Subtotal = $43,872,265

Issue Date FY: 2022 ( Subtotal = $46,891,131 )
2022	2022	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	004	1	7/29/2022	SUPPLEMENT FOR EXPANSION	$10,069,899
2022	2022	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	000	1	1/7/2022	SUPPLEMENT FOR EXPANSION	$4,850,000
2022	2022	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	003	1	4/15/2022	SUPPLEMENT FOR EXPANSION	$4,516,054
2022	2022	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	001	1	1/12/2022	SUPPLEMENT FOR EXPANSION	$1,990,662
2022	2022	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	006	1	8/4/2022	SUPPLEMENT FOR EXPANSION	$25,464,516
2022	2022	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	002	1	2/18/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2020	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	005	1	8/1/2022	NEW	$0
														Subtotal = $46,891,131

Issue Date FY: 2021 ( Subtotal = $41,719,530 )
2021	2021	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	001	1	4/29/2021	SUPPLEMENT FOR EXPANSION	$4,166,064
2021	2021	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	21st Century Cures Act - Precision Medicine Initiative	005	1	9/20/2021	SUPPLEMENT FOR EXPANSION	$2,549,098
2021	2021	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	004	1	8/30/2021	SUPPLEMENT FOR EXPANSION	$31,078,193
2021	2021	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	002	1	4/30/2021	SUPPLEMENT FOR EXPANSION	$2,645,217
2021	2021	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	000	1	4/27/2021	SUPPLEMENT FOR EXPANSION	$1,280,958
2021	2021	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	21st Century Cures Act - Precision Medicine Initiative	006	1	9/23/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	VIGNET INC.	4114 LEGATO RD #900	FAIRFAX	VA	22033	FAIRFAX	USA	Trans-NIH Research Support	003	1	7/30/2021	NEW	$0
														Subtotal = $41,719,530

Grand Total All Awards = $151,076,992

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PTSC 2.0

Award Number: OT2OD030043

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: OTHER

PERIOD OF PERFORMANCE START DATE: 08/14/2020

PERIOD OF PERFORMANCE END DATE: 02/28/2025

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