Public Health Emergency Preparedness (PHEP) Cooperative Agreement - New York City has responded to numerous recent significant public health threats, including COVID-19, mpox, measles, Zika virus, Legionnaires disease, Ebola virus, and Hurricane Sandy, which underscore the importance of effective planning and response capabilities that can be applied to all hazards. As new threats, including novel infectious diseases, emerge, DOHMH must continue to strengthen and enhance the capabilities of the NYC medical and public health systems to prepare for, respond to and recover from evolving threats and other emergencies. More effective responses will enable DOHMH and the NYC healthcare system to prevent or reduce morbidity and mortality from incidents whose scale, rapid onset, or unpredictability stresses the public health and health care systems and to ensure the earliest possible recovery and return of the public health and health care systems to pre-incident levels or improved functioning. In order to support its ability to prevent, prepare for, respond to, and recover from health emergencies, DOHMH has identified key activities for the upcoming five-year project period that align with the Public Health Preparedness and Response capabilities and the Response Readiness Framework priorities. Expected outcomes over the project period include: • Improved public health readiness, response, and recovery capability that follows standardized emergency management practices. • Implementation of timely public health recommendations and control measures for all hazards. • Earliest identification and investigation of incidents with public health impact. • Enhanced ability of laboratories to respond to public health incidents by applying modern methods. • Timely communication of situational awareness and risk information. • Timely coordination and support of response and recovery activities with health care systems and partners. • Integration of equity into public health response and recovery. • Prepared public health workforce ready to sustain public health investigations, response, and recovery. • Active engagement in communities of practice. • Earliest possible recovery and return of the public health system to pre-incident levels or improved functioning. • Prevention or reduction of morbidity and mortality for all impacted populations from incidents with public health consequences whose scale, rapid onset, or unpredictability stresses the public health system. Additionally, to ensure comprehensive, effective response coordination, DOHMH will continue to develop and leverage its inter- and intra-agency and non-government (e.g. community-based organizations) relationships, which are integral to preparing for, responding to and recovering from large-scale emergencies.