Public Health Crisis Response Cooperative Agreement - During the last few years California has seen a significant number of public health and medical emergencies requiring activation of its emergency response system at the state and/or local level, with COVID-19 Pandemic being the longest activation to date. In 2020, the California Department of Public Health (CDPH) Medical and Health Coordination Center was activated to support local and statewide response for COVID-19 Pandemic infectious disease, and also devastating wildfires. Many of California’s local health departments (LHDs) were activated for these same events, along with extreme heat and cold weather events; and acts of domestic terrorism. California remains at risk for a number of potentially catastrophic emergencies that would have a significant impact on the public health and medical system. The purpose of these funds would be for CDPH to support a collaborative effort at both the state and local level to rapidly mobilize and respond to a public health emergency identified by CDC. CDPH and LHDs will engage in activities designed to mobilize, strengthen and enhance the capacity of the public health and medical system to respond to the identified emergency and to bring about the following high-level outcomes. • Earliest possible activation and management of emergency operations — CDPH and LHDs will enhance capabilities and reduce cycle times to hire, train and deploy staff, purchase equipment and supplies; and stand up EOCs and call centers. • Prioritized public health services and resources sustained throughout all phases of emergencies and incidents — CDPH and LHDs will conduct assessments, work with partners, and revise and train on response plans and guidance to address at-risk population needs and the identified pathogen in infectious disease situations. • Timely implementation of intervention and control measures — CDPH and LHDs will procure resources, vaccines, and treatment medications, conduct case management, strategically position response activities, and create and distribute guidance to prevent the spread of the disease. • Timely communication of risk and essential elements of information by partners — CDPH and LHDs will develop, distribute, and translate risk communication materials to educate the community and partners. • Timely coordination and support of response activities with healthcare and other partners — LHDs will hire and deploy staff and resources to support the expansion of the healthcare delivery system, provide situational awareness and population monitoring, and conduct coordination of volunteers. • Continuous learning and improvements contain real-time feedback loop — Both the state and LHDs will seek opportunities for real-time feedback that can lead to continuous improvements.