Michigan Colorectal Cancer Control Program - The Michigan Department of Health and Human Services (MDHHS) is applying for $813,280 of federal funds to bring together a network of primary care clinics, health systems, and supporting partners to address disparities in colorectal cancer (CRC) screening at the clinic level. In Michigan (MI), colorectal cancer (CRC) is the fourth most diagnosed cancer and the second leading cause of non-sex-specific cancer deaths (1,2). According to estimates from the 2022 MI Behavioral Risk Factor Survey (MIBRFS), 75.1% of adults ages 50 and older are up to date on colorectal cancer (CRC) screening, which represents a 0.6% increase in statewide screening since the 2020 grant application (DP20-2002) and a 5.5% increase since the 2015 grant application (DP15-1502). Although, the statewide CRC screening rate is higher than the national rate, there are clear disparities in MI CRC screening and burden that emerge when reviewing geographic, population-level, and clinic-level data. In response to these disparities, MDHHS is prepared to partner directly with primary care clinics that serve underserved populations to implement evidence-based interventions (EBIs) aimed at increasing the CRC screening rate at the clinic-level. The purpose of MDHHS’ proposal is to increase CRC screening rates at clinics that serve underserved populations. The MCRCCP will rely on a network of program partners (supporting partners) to further enhance efforts and offer partner clinics access to quality improvement, staff training, and health information technology support. Building upon the past 15 years of successful experience under CRCCP-DP09-03, CRCCP-DP15-1502 and CRCCP-DP20-2002, MDHHS will increase CRC screening in partner clinics. MDHHS will achieve this outcome by increasing implementation of high quality EBIs and increasing stool test kits returned and completion of coloscopy procedures in partner clinics. It is also anticipated that as partner clinics increase implementation of multi-component EBIs, barriers that drive inequities will be reduced contributing to decreased health disparities in the populations of focus. Ultimately, the achievement of the short-term outcomes will lead to achievement of intermediate and long-term outcomes, including increased CRCs prevented, increased diagnosis of early-stage CRC, and decreased CRC incidence and mortality. 1 Michigan Resident Cancer Incidence File. Michigan Department of Health and Human Services, Division for Vital Records and Health Statistics, Michigan Cancer Surveillance Program. 2 Michigan Resident Death Files. Michigan Department of Health and Human Services, Division for Vital Records and Health Statistics.