In Tennessee, pre-diabetes, diabetes, cardiovascular disease, certain cancers, and other chronic conditions disproportionately impact racial and ethnic minority populations, and their effects are magnified for persons living in poverty. Therefore, it is critical that contributing risk factors such as obesity, poor nutrition, and physical inactivity are addressed through upstream and early prevention strategies, as well as efforts that are intentional in reaching populations experiencing the largest burden of associated chronic conditions. It is the intent of this application to leverage current and new strategies and partnerships to implement evidence-based, culturally tailored strategies at the local level to address disparities among the non-Hispanic Black and Hispanic/Latino populations. Anticipated outcomes include increasing access to high quality nutrition, safe places for physical activity, facilitating linkages to community-based health programs, and increasing adult vaccinations where disparities are most prevalent among the priority populations.