American Cancer Society Comprehensive Cancer ControlTechnical Assistance and Training Program - This application is being submitted in response to CDC-RFA-DP-23-0017 Notice of Funding Opportunity Component A. As the nation’s leading, nationwide, voluntary health organization focused on cancer, the American Cancer Society (ACS) is ideally positioned to design and deliver training and technical assistance (TTA) to funded recipients of the CDC National Comprehensive Cancer Control Program (NCCCP). ACS has worked collaboratively with CDC to deliver TTA to NCCCP recipients for over 25 years. Building on our successes, coupled with extensive subject-matter expertise from across our organization, ACS will deliver timely and innovative TTA that empowers NCCCP recipients to implement policy, systems and environmental change strategies from their jurisdictional cancer plans. ACS will measure the impact of TTA through progress towards the following outcomes: Short-term outcomes: Increased reach of TTA activities to NCCCP recipients; and increased knowledge, awareness and attitudes regarding evidence-based interventions and resources that aid implementation; Intermediate Outcome: Increased adoption of strategies and evidence-based interventions to improve and sustain NCCCP recipients’ efforts; and Long-term Outcome: Increased capacity, reach, utilization, impact and sustainability of NCCCP recipients. To successfully meet these outcomes, ACS will implement a robust TTA plan which includes conducting regular Communities of Practice (CoPs), delivering high-quality trainings and developing data driven, evidence-based, application-focused resources on approaches that impact health equity by addressing social determinants of health and spans the cancer continuum; require collaboration across multiple organizational sectors; and operate at the policy, systems and environmental change level to maximize impact and ensure sustainability. ACS will utilize its broad base of subject matter experts in cancer prevention, screening, early detection, treatment, survivorship, health equity, research, evaluation, surveillance, advocacy and clinical care, as well as the expertise throughout leadership of the ACS’s six National Cancer Roundtables, and staff members from across the nation who liaise with state cancer coalitions, to collaborate in delivery of TTA to NCCCP recipients.