Colorado Cancer Prevention and Control - The Colorado Department of Public Health and Environment (CDPHE) proposes to address cancer prevention and control in Colorado through the submission of applications for all three program areas of the “Cancer Prevention and Control Programs for State, Territorial, and Tribal Organizations,” CDC-RFA-DP22-2202. Program 1: National Breast and Cervical Cancer Early Detection Program (NBCCEDP) Women’s Wellness Connection (WWC) is Colorado’s NBCCEDP program. WWC proposes to prioritize funding and activities towards priority populations of women most disproportionately burdened by breast and cervical cancer by using a multi-modal approach including provision of breast and cervical cancer screening and follow-up, provision of patient navigation, provision of community outreach, and implementation of evidence-based interventions (EBI). Through implementation of the four strategies (Strategies 2-5) described in this application, by the end of the project period (June 29, 2027). WWC will achieve the bolded Short-term and Intermediate Outcomes from the NBCCEDP Logic Model. Achievement of these outcomes will result in an eventual decrease in cancer incidence, morbidity and mortality and reduction in cancer disparities. Program 2: National Comprehensive Cancer Control Program (NCCCP) The Colorado Comprehensive Cancer Program (CCCP) proposes to advance work and partnerships toward Coloradans being free of cancer and improve health equity through primary prevention (obesity reduction), early detection and screening (increasing access and use of lung, colorectal, breast, and cervical cancer screening), and promoting health and wellness in cancer survivors. CCCP will analyze data to describe Colorado’s burden of cancer, and collaborate with the Colorado Cancer Coalition (CCC) to make evidence- and data-based decisions regarding cancer plan contents and cancer coalition priorities. Through implementation of all five program strategies as identified in the NOFO, CCCP intends to achieve short- and intermediate-term outcomes that aid in reaching long-term outcomes of reduced cancer risk, increased quality of life among cancer survivors, decreased cancer incidence, morbidity, mortality, and reduced cancer disparities. Program 3: National Program of Cancer Registries ( NPCR) The Colorado Central Cancer Registry (CCCR) is Colorado’s statewide cancer surveillance program located within the Colorado Department of Public Health and Environment. The CCCR has been in operation since 1968 and is population-based for the Denver metropolitan area since 1979 and statewide since 1988. The mission of the CCCR is to reduce death and illness due to cancer by providing data on treatment, incidence, deaths, and survival. NPCR funds will allow the CCCR to implement all four NPCR program strategies and achieve short and intermediate-term outcomes over this five-year period. The CCCR will monitor cancer burden through a comprehensive system of surveillance, successfully adopt data modernization strategies to improve timeliness, quality, and completeness of surveillance data, and make population-based cancer surveillance data available for use by multiple internal and external partners to inform policy, systems, and environmental changes which are intended to decrease the burden of cancer in Colorado.