Michigan Cancer Prevention and Control Program - Cancer is the second leading cause of death in Michigan (MI). In 2018, there were 56,505 new cases of invasive cancer diagnosed in MI, and in 2020, 21,118 residents died from the disease. To reduce the burden of cancer, the MI Department of Health and Human Services (MDHHS) is applying for Programs 1, 2, and 3 of CDC-RFA-DP22-2202. Program 1: The purpose of the MI Breast and Cervical Cancer Control Navigation Program (BC3NP) is to increase breast and cervical cancer screening rates among underserved low-income women < 250% Federal Poverty Level. Through the program, evidence-based interventions will be implemented to resolve barriers so eligible women can receive needed breast and cervical cancer screening, diagnostic and treatment services. The MI BC3NP is requesting a total of $5,161,501 to achieve the outcomes of this proposal by supporting its 25 contracted agencies to provide services to 7,412 program women. Program 2: The purpose of MI’s Comprehensive Cancer Control (MCCCP) proposal is to provide a coordinated approach to inform policy, systems, and environmental changes that decrease the cancer burden. MI’s Cancer Plan 2021-2030 includes 52 objectives designed to have a measurable impact on cancer. Each objective is supported by evidence-based interventions. The MDHHS and the MI Cancer Consortium, the state’s cancer control coalition, will continue to implement cancer plan interventions while monitoring changes in the cancer burden through surveillance. Populations that experience disparities will receive emphasis. MI is requesting a total of $538,000 for the MCCCP. Program 3: The purpose of the MI Cancer Surveillance Program’s (MCSP) proposal is to collect state-wide cancer incidence data by type and areas of residence. Timely, complete and accurate information on cancer cases is employed as a basis for cancer surveillance, as a tool for evaluation of cancer incidence within regions of particular interest, and as a source of baseline incidence data. Registry data is of value in examining the frequency of cancer by demographic characteristics such as age, race and sex and is of significant value to researchers in epidemiologic case control studies. Incidence data is used in the areas of planning health education and addressing public health concerns. Data is used for evidence-based decisions for program planning, implementation and evaluation through collaboration with health agencies, tribes and organizations, territorial health agencies, and other stakeholders, including the MCCCP and the BC3NP to decrease cancer incidence, morbidity, and mortality by identifying populations who have increased cancer risk due to health disparities. To achieve the outcomes of this proposal, MI is requesting a total of $1,099,999 for the MCSP. Estimated number of people to be served as a result of the award of this grant: 10,050,811